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Acetazolamide 500mg Powder for solution for injection
Acetazolamide 500mg Powder for solution for injection
Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or nurse.
If you get any side effects, talk to your doctor or nurse. This includes any possible side effects not listed in this leaflet. See section 4.
The name of your medicine is Acetazolamide Sodium 500mg Powder for Solution for Injection. It will be referred to as Acetazolamide Injection for ease of use hereafter.
1. What Acetazolamide injection is and what it is used for
2. What you need to know before you are given Acetazolamide injection
3. How you are given Acetazolamide injection
4. Possible side effects
5. How to store Acetazolamide injection
6. Contents of the pack and other information
Acetazolamide injection contains the active substance Acetazolamide. This belongs to a group of medicines known as carbonic anhydrase inhibitors.
Acetazolamide injection is used to treat:
Speak to your doctor if any of the above applies to you.
Talk to your doctor or nurse before are given Acetazolamide injection if:
A small number of people being treated with anti-epileptics such as Acetazolamide have had thoughts of harming or killing themselves, if at any time you have these thoughts, immediately contact your doctor.
A decrease in vision or eye pain could be symptoms of fluid accumulation in the vascular layer of the eye (choroidal effusion or choroidal detachment). This can happen within hours of taking Acetazolamide Injection. Talk to your doctor promptly if you experience these symptoms.
Tell your doctor or nurse if you are taking or have recently taken or might take any other medicines.
The effects of any of these medicines may change, particularly if you are taking, or using, any of the following:
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking any medicines.
Acetazolamide injection SHOULD NOT be taken if you are pregnant, think you are pregnant or are planning to become pregnant.
It may be taken when breast feeding but only on the advice of the doctor.
If Acetazolamide injection makes you feel drowsy or confused, you should not drive or operate machines. Acetazolamide injection can occasionally cause short-sightedness; if this happens and you feel that you can no longer drive safely, you should stop driving and contact your doctor.
This medicine contains less than 1 mmol sodium (23mg) per dose, i.e. essentially “sodium-free”.
Always use this medicine exactly as your doctor has told you. Check with your doctor if you are not sure.
The recommended dose is:
Adults: 250 - 1000mg per 24 hours, usually in separate doses for amounts over 250mg daily.
ii) Fluid retention (Congestive heart-failure, drug-induced oedema): The usual dose is 250 - 375mg once daily in the morning.
Fluid retention associated with pre-menstrual tension: The usual dosage is 125-375mg as a single dose.
Adults: The usual dosage is 250 - 1000mg daily in separate doses.
Use in Children: The usual dose is 8 - 30mg/kg in daily separate doses and should not to exceed 750mg/day.
Acetazolamide injection is a white powder which firstly dissolved in water to make a solution for injection either into one of your veins (intravenous) or into one of your muscles (intramuscular). The dose varies from person to person depending on their condition. Your doctor will decide on the most appropriate dose. Before, starting and during treatment your doctor will monitor your blood to check that treatment with Acetazolamide injection is suitable for you.
As the injection will be administered by a doctor, it is unlikely that you will be given more than is necessary.
If you have any further questions on the use of this medicine, ask your doctor or nurse.
Like all medicines, Acetazolamide injection can cause side effects, although not everybody gets them.
All medicines can cause allergic reactions although serious allergic reactions are very rare. Any sudden wheeziness, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) should be reported to a doctor immediately.
Contact a doctor immediately if you experience a serious skin reaction: a red, scaly rash with bumps under the skin and blisters (exanthematous pustulosis). The frequency of this side effects is not known (cannot be estimated from the available data).
Not known (frequency cannot be estimated from the available data)
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side-effects you can help provide more information on the safety of this medicine.
Keep out of the reach and sight of children.
Do not use this medicine after the expiry date which is stated on the label and carton. The Expiry date refers to last day of that month.
Do not store above 25°C
Any unused solution can be stored in a refrigerator for up to 24 hours but any unused solution after this period must be discarded.
For single use only.
Do not throw away any medicines via wastewater. Ask your pharmacist how to throw away of medicines you no longer use. These measures will help to protect the environment.
The active substance is acetazolamide. Each vial contains 500mg acetazolamide.
The other ingredients are sodium hydroxide, hydrochloric acid and water for injections.
Acetazolamide injection is a white powder, packed in glass vials with a rubber ring and aluminium seal.
Before use, it is made into a solution, using at least 5ml water for injection.
This leaflet was last revised in November 2023.