Active ingredient
- desmopressin acetate
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 35533/0010.
Desmopressin Acetate Tablets 100 & 200 microgram
PACKAGE LEAFLET: INFORMATION FOR THE USER
Desmopressin Acetate Tablets
100 & 200 microgram
The name of your medicine is Desmopressin acetate tablets, which will be referred to as ‘Desmopressin’ or ‘Desmopressin tablets’ throughout this leaflet.
Read all of this leaflet carefully before you start taking this medicine.
In this leaflet:
1. What Desmopressin is and what it is used for
2. Before you take Desmopressin
3. How you take Desmopressin
4. Possible side effects
5. How to store Desmopressin
6. Further information
1 What Desmopressin is and what it is used forwhat for
Desmopressin tablets are round, white tablets. They contain the active ingredient desmopressin acetate hydrate.
Desmopressin tablets are used for the treatment of:
2 Before you take Desmopressin
Do not take Desmopressin tablets (and talk to your doctor) if you:
Take special care with Desmopressin tablets (and talk to your doctor) if you:
Bed Wetting
If you are being treated with Desmopressin for bed-wetting, your fluid intake must be limited from 1 hour before until 8 hours after taking the tablets. You should avoid drinking water while swimming and you should stop taking Desmopressin if you are vomiting or have diarrhoea until your fluid balance is back to normal.
Fluid/Salt Disorder
You must be careful not to drink too much fluid if you have a condition that causes a fluid or salt disorder or if you are at risk of increased intracranial pressure (pressure on the brain).
It is important to monitor body weight and blood pressure during treatment with Desmopressin.
Taking other medicines
Please tell your doctor or pharmacist if you are taking, or have recently taken, any other medicines, including medicines obtained without a prescription. This is especially important of the following substances as they may interact with your Desmopressin tablets:
It may still be all right for you to be given Desmopressin and your doctor will be able to decide what is suitable for you.
Pregnancy and breast-feeding
Tell your doctor if you are pregnant or breast-feeding. Your doctor may want to monitor your blood pressure if you are pregnant.
Driving and using machines
Desmopressin has no effect on driving or using machines.
Important information about some of the ingredients of Desmopressin tablets
Desmopressin tablets contain lactose, which is a type of sugar. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
3 How you take Desmopressin
Dosage
Desmopressin tablets are taken by mouth.
Always take Desmopressin exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
Treatment of Diabetes Insipidus:
The starting dose in adults and children is 100 micrograms, three times daily. The dose should then be adjusted according to the patient’s response.
For most patients, the adjusted dose is 100 to 200 micrograms, three times daily.
Post-hypophysectomy polyuria/polydipsia:
The dose of Desmopressin depends on the concentration of the urine.
Primary nocturnal enuresis:
The usual dose for children (from 5 years of age) and adults (up to 65 years of age) is 200 micrograms at bedtime. If necessary, your doctor may increase the dose to 400 micrograms.
The need for continued treatment should be reassessed after 3 months by stopping treatment with Desmopressin for at least one week.
If it appears that Desmopressin is not having an effect at low doses, your doctor may tell you not to take the tablets with food.
If you take more Desmopressin than you should
Go to the accident and emergency department at the nearest hospital straight away. Take the Desmopressin pack with you.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4 Possible side effects
Like all medicines, Desmopressin tablets can cause side effects, although not everybody gets them.
All medicines can cause allergic reactions, although serious allergic reactions are very rare.
Stop taking Desmopressin tablets and tell your doctor or go to the nearest hospital casualty department straight away if you experience any of the following:
The following side effects have been reported:
Treatment with Desmopressin without reducing fluid intake may cause water retention or low sodium levels. Low sodium levels can cause the following side effects:
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme (website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store).
By reporting side effects you can help provide more information on the safety of this medicine.
5 How to store Desmopressin
Desmopressin tablets should be kept out of the sight and reach of children.
Do not use Desmopressin after the expiry date which is stated on the carton. The expiry date refers to the last day of that month.
Store below 25°C. Store in the original package.
Keep the bottle tightly closed. Keep the bottle in the outer carton.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer needed. These measures will help to protect the environment.
6 Further information
What Desmopressin tablets contain
The active substance is desmopressin acetate hydrate.
The other ingredients are: lactose monohydrate, potato starch, povidone, magnesium stearate and colloidal anhydrous silica.
What Desmopressin tablets look like and contents of the pack
30ml plastic bottles with a tamper-proof, twist-off cap and a silica gel desiccant insert. Each bottle contains either 30 or 90 tablets. The tablets are white, round and convex with break marks.
Not all pack sizes may be marketed.
Marketing Authorisation Holder
Manufacturer
This leaflet was last revised in January 2021
8094717-04
Under licence from
1010046-P6.8
110084
4 Rotherbrook Court, Bedford Road, Petersfield, Hampshire, GU32 3QG, UK
+44 (0)1730 231148
+44 (0)1730 231148