Anadin ORIGINAL
CONTAINS ASPIRIN AND CAFFEINE
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. Keep this leaflet. You may need to read it again. If you have any further questions, ask your pharmacist. If you get any side effects, talk to your pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
1. What your medicine is and what it is used for
2. What you need to know before you take your medicine
3. How to take your medicine
4. Possible side effects
5. How to store your medicine
6. Contents of the pack and other information
Each tablet contains: Aspirin and Caffeine. Aspirin belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) that work by relieving pain and reducing inflammation, high temperature and fever. In addition, your medicine contains caffeine, which increases the pain-relieving effect of the product. Your medicine is for effective relief from: mild to moderate pain including headache, migraine, sharp nerve pain (neuralgia), toothache, sore throat, period pains and aches and pains, symptomatic relief of sprains, strains, rheumatic pain, nerve pain of the lower back or legs (sciatica), lower back pain (lumbago), chronic muscle pain, sometimes with tiredness and skin sensitivity (fibrositis), muscular aches and pains, joint swelling and stiffness, influenza, feverishness and feverish colds.
- are allergic to aspirin or any of the other ingredients listed in this leaflet.
- suffer from asthma, bronchospasm, angioedema, urticaria, or acute rhinitis caused by aspirin or other NSAIDs.
- have ever had a stomach ulcer, perforation or bleeding.
- suffer from haemophilia, other clotting disorders or take medicines that affect the way your blood clots (e.g. warfarin, other anticoagulants, or alteplase).
- are suffering from kidney or liver failure
- have a history of gout
- Do not give to children under 16 years unless on the advice of a doctor. There is a possible association between aspirin and Reye’s syndrome when given to children. Reye’s syndrome is a very rare disease, which affects the brain and liver and can be fatal. For this reason aspirin should not be given to children aged under 16 years, unless on the advice of a doctor.
Talk to your doctor or pharmacist before taking this medicine if you:
- suffer from asthma, allergic disease, nasal polyps, dehydration, liver or kidney problems, have hypertension, are diabetic or G-6-PD deficiency (an hereditary condition leading to low red blood cell counts).
When taking acetylsalicylic acid, serious allergic reactions which may include chest pain and even heart attack (Kounis syndrome) have been reported (see section 4). Seek medical care immediately when you notice chest pain with allergic reactions (such as skin rashes, shortness of breath).
Do not use this medicine if you are taking medicines that reduce blood clotting (warfarin) or for treatment of gout (sulfinpyrazone, probenecid).
Talk to your doctor or a pharmacist if you are taking other NSAIDS, steroid hormones (corticosteroids), water tablets, diuretics (furosemide e.g. Amiloride, Spironolactone, Eplerenone ) and antihypertensives (beta blockers, ACE inhibitors), anticoagulants, treatments for epilepsy (phenytoin, valproate), diabetes (sulphonylureas), methotrexate (to treat some kinds of cancer, arthritis or psoriasis), thrombotics (alteplase), blood pressure lowering treatments (ACE inhibitors), antacids, treatments for leg pain when walking (cilostazol), and treatment of some depressive disorders (SSRIs, venlafaxine). Caffeine may cause further increases in blood pressure and heart rate when combined with other nerve stimulants (ephedrine). Carbonic anhydrase inhibitors, such as acetazolamide (to treat glaucoma, seizure, or to increase urine production).
Do not use this medicine if you are in late stages of pregnancy or if you are breast feeding.
For oral administration and short term use only. Dosage: Adults, the elderly and young persons aged over 16: The minimum effective dose should be used for the shortest time necessary to relieve symptoms. Take 1 to 2 tablets every 4 to 6 hours, as required. The tablets should be taken with water. Take only as much as you need to relieve your symptoms and leave at least 4 hours between each dose. Do not take more than 12 tablets in any 24 hour period. Do not give to children aged under 16 years, unless on the advice of a doctor. For the treatment of migraines, do not give to children and adolescents under the age of 18. Do not exceed the stated dose. If symptoms persist for more than 3 days, or if symptoms worsen consult your doctor or pharmacist.
If you take too many tablets contact your doctor or hospital immediately. Bring any remaining tablets with you to show the doctor.
Like all medicines, your medicine can cause side effects, although not everybody gets them. You can reduce the chances of experiencing side effects by using the minimum dose required. Side effects may be more serious in elderly patients. If you experience any of the following serious effects STOP taking this medicine immediately and contact your doctor or pharmacist:
- Stomach ulceration or perforation: Symptoms could include severe abdominal pain, vomiting blood (or liquid with what looks like coffee grounds), blood in the faeces (stools/motions) or passing black stools.
- Severe allergic reactions: Symptoms could include difficulty breathing, itchy rash or swollen facial features, runny nose, skin reactions and anaphylaxis.
- Chest pain with allergic reactions (such as skin rashes, shortness of breath); this can be a sign of a potentially serious allergic reaction (Kounis syndrome) (frequency not known).
- Breathing problems: Wheezing and breathing difficulties may be triggered in patients suffering from or with a previous history of asthma.
If any of the side effects gets serious or if you notice any side effect not listed in this leaflet, please tell your doctor or pharmacist:
- Occasionally the blood does not clot well, which may result in easy bruising or bleeding.
- High caffeine intake can result in tremor (shaking) and palpitations (uncomfortable feeling in the chest caused by fluttering heartbeat).
- Aspirin may trigger gout in people prone to it.
- Other side effects include indigestion, heartburn, feeling or being sick, temporary hearing loss, ringing in the ears, nervousness, restlessness, irritability, dizziness, insomnia and anxiety.
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side effects you can help provide more information on the safety of this medicine.
- Do not use this medicine after the expiry date shown on the end of the carton.
- Do not store above 25ºC.
- Keep out of sight and reach of children.
What your medicine contains: The active substances are Aspirin and Caffeine. Each tablet contains 325 mg of Aspirin and 15 mg of Caffeine. The other excipients are: quinine sulfate, microcrystalline cellulose (E460), maize starch, calcium stearate, hypromellose (E464) and macrogol.
Your medicine is available in packs containing 12 and 16 tablets. Not all pack sizes may be marketed.
Manufacturer:
Haleon Italy Manufacturing S.r.l.
Via Nettunense
90 - 04011
Aprilia (LT)
Italy
Marketing Authorisation Holder:
Haleon UK Trading Limited
Weybridge
KT13 0NY
U.K.
This leaflet was last revised in August 2026.
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