Anadin Original

1. What your medicine is and what it is used for
2. What you need to know before you take your medicine
3. How to take your medicine
4. Possible side effects
5. How to store your medicine
6. Contents of the pack and other information

• are allergic to aspirin or any of the other ingredients listed in this leaflet.
• suffer from asthma, bronchospasm, angioedema, urticaria, or acute rhinitis caused by aspirin or other NSAIDs.
• have ever had a stomach ulcer, perforation or bleeding.
• suffer from haemophilia, other clotting disorders or take medicines that affect the way your blood clots (e.g. warfarin, other anticoagulants, or alteplase).
• are suffering from kidney or liver failure
• have a history of gout
• Do not give to children under 16 years unless on the advice of a doctor. There is a possible association between aspirin and Reye’s syndrome when given to children. Reye’s syndrome is a very rare disease, which affects the brain and liver and can be fatal. For this reason aspirin should not be given to children aged under 16 years, unless on the advice of a doctor.

Talk to your doctor or pharmacist before taking this medicine if you:

• suffer from asthma, allergic disease, nasal polyps, dehydration, liver or kidney problems, have hypertension, are diabetic or G-6-PD deficiency (an hereditary condition leading to low red blood cell counts).

When taking acetylsalicylic acid, serious allergic reactions which may include chest pain and even heart attack (Kounis syndrome) have been reported (see section 4). Seek medical care immediately when you notice chest pain with allergic reactions (such as skin rashes, shortness of breath).

Do not use this medicine if you are taking medicines that reduce blood clotting (warfarin) or for treatment of gout (sulfinpyrazone, probenecid).

Talk to your doctor or a pharmacist if you are taking other NSAIDS, steroid hormones (corticosteroids), water tablets, diuretics (furosemide e.g. Amiloride, Spironolactone, Eplerenone ) and antihypertensives (beta blockers, ACE inhibitors), anticoagulants, treatments for epilepsy (phenytoin, valproate), diabetes (sulphonylureas), methotrexate (to treat some kinds of cancer, arthritis or psoriasis), thrombotics (alteplase), blood pressure lowering treatments (ACE inhibitors), antacids, treatments for leg pain when walking (cilostazol), and treatment of some depressive disorders (SSRIs, venlafaxine). Caffeine may cause further increases in blood pressure and heart rate when combined with other nerve stimulants (ephedrine). Carbonic anhydrase inhibitors, such as acetazolamide (to treat glaucoma, seizure, or to increase urine production).

Do not use this medicine if you are in late stages of pregnancy or if you are breast feeding.

If you take too many tablets contact your doctor or hospital immediately. Bring any remaining tablets with you to show the doctor.

If any of the side effects gets serious or if you notice any side effect not listed in this leaflet, please tell your doctor or pharmacist:

• Occasionally the blood does not clot well, which may result in easy bruising or bleeding.
• High caffeine intake can result in tremor (shaking) and palpitations (uncomfortable feeling in the chest caused by fluttering heartbeat).
• Aspirin may trigger gout in people prone to it.
• Other side effects include indigestion, heartburn, feeling or being sick, temporary hearing loss, ringing in the ears, nervousness, restlessness, irritability, dizziness, insomnia and anxiety.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine.