The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 25258/0079 .
Rizatriptan 5 mg, 10 mg Tablets
Rizatriptan 5 mg Tablets
Rizatriptan 10 mg Tablets
1. What Rizatriptan is and what it is used for
2. What you need to know before you take Rizatriptan
3. How to take Rizatriptan
4. Possible side effects
5. How to store Rizatriptan
6. Contents of the pack and other information
Rizatriptan are used to treat migraine attacks. Do not use them to prevent an attack.
Rizatriptan belongs to a class of medicines called selective serotonin 5-HT1B/1D receptor agonists.
Rizatriptan is used to treat the headache phase of the migraine attack in adults.
Treatment with Rizatriptan:
Reduces swelling of blood vessels surrounding the brain. This swelling results in the headache pain of a migraine attack.
If you are not sure if any of the above apply to you talk to your doctor or pharmacist before taking Rizatriptan.
Talk to your doctor or pharmacist before taking Rizatriptan:
If you take Rizatriptan too often this may result in you getting a chronic headache. In such cases you should contact your doctor as you may have to stop taking Rizatriptan.
Please tell your doctor or pharmacist about your symptoms. Your doctor will decide if you have migraine. You should take Rizatriptan only for a migraine attack. Rizatriptan should not be used to treat headaches that might be caused by other, more serious conditions.
Please tell your doctor or pharmacist if you are taking or have recently taken, or plan to take, any other medicines including medicines obtained without a prescription. This includes herbal medicines and those you normally take for a migraine. This is because Rizatriptan can affect the way some medicines work. Also other medicines can affect Rizatriptan.
There is no experience with the use of Rizatriptan in children and adolescents under 18 years of age, therefore children and adolescents should not be given Rizatriptan.
There have been no full studies to look at how safe and effective Rizatriptan is amongst patients older than 65 years.
Do not take Rizatriptan if you :
The above listed medicines when taken with Rizatriptan may increase the risk of side-effects.
You should wait at least 6 hours after taking Rizatriptan before you take ergotamine-type medicines such as ergotamine or dihydro-ergotamine or methysergide.
You should wait at least 24 hours after taking ergotamine-type medicines before taking Rizatriptan.
Ask your doctor for instructions and the risks about taking Rizatriptan if you are taking :
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Rizatriptan can take longer to work if it is taken after food. Although it is better to take it on an empty stomach, you can still take it if you have eaten.
It is not known whether Rizatriptan is harmful to an unborn baby when taken by a pregnant woman.
If you are pregnant or breast feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Breastfeeding should be avoided for 24 hours after treatment.
You may feel sleepy or dizzy while taking Rizatriptan. If this happens, do not drive or use any tools or machines.
Aspartame contains a source of phenylalanine and this may be harmful for people with phenylketonuria.
Rizatriptan is used to treat migraine attacks. Take Rizatriptan as soon as possible after your migraine headache has started. Do not use it to prevent an attack.
Always take Rizatriptan exactly as your doctor has told you. You should check with your doctor or your pharmacist if you are not sure.
Rizatriptan should be taken by mouth and swallowed whole with liquid.
The recommended dose is 10 mg.
If you are currently taking propranolol or have kidney or liver problems you should use the 5 mg dose of Rizatriptan. You should leave at least 2 hours between taking propranolol and Rizatriptan up to a maximum of 2 doses in a 24 hour period.
In some patients, migraine symptoms can return within a 24-hour period. If your migraine does return you can take an additional dose of Rizatriptan. You should always wait at least 2 hours between doses.
If you do not respond to the first dose of Rizatriptan during an attack, you should not take a second dose of Rizatriptan for treatment of the same attack. It is still likely, however, that you will respond to Rizatriptan during the next attack.
Do not take more than 2 doses of Rizatriptan in a 24-hour period,(for example, do not take more than two doses of 10 mg or 5 mg tablets in a 24-hour period). You should always wait at least 2 hours between doses.
If your condition worsens, seek medical attention.
Rizatriptan benzoate tablets is also available as a 5 mg and 10 mg orodispersible tablets that dissolves in the mouth. The ordispersible tablets can be used in situations in which liquids are not available, or to avoid the nausea and vomiting that may accompany the ingestion of tablets with liquids.
If you take more Rizatriptan than you should, talk to your doctor or pharmacist straight away. Take the medicine pack with you.
Signs of overdose can include dizziness, drowsiness, vomiting, fainting and slow heart rate.
If you have any further questions on the use of this product ask your doctor or pharmacist.
Like all medicines, Rizatriptan can cause side effects, although not everybody gets them. The following side effects may happen with this medicine.
Tell your doctor right away if you have symptoms of allergic reactions, serotonin syndrome, heart attack or stroke.
In addition, tell your doctor if you experience any symptoms that suggest an allergic reaction (such as a rash or itching) after taking Rizatriptan.
In adult studies, the most common side effects reported were dizziness, sleepiness and tiredness.
Common (may affect up to 1 in 10 people)
Uncommon (may affect up to 1 in 100 people)
Rare (may affect up to 1 in 1,000 people)
Not known (frequency cannot be estimated from the available data):
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.co.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.
Keep Rizatriptan out of the sight and reach of children.
Do not use Rizatriptan after the expiry date which is stated on the container after EXP. The expiry date refers to the last day of the month.
This medicinal product does not require any special storage conditions.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use.These measures will help protect the environment
The active substance of Rizatriptan is rizatriptan.
One 5 mg tablet contains 5 mg rizatriptan as 7.265 mg of rizatriptan benzoate
One 10 mg tablet contains 10 mg rizatriptan as 14.53 mg of rizatriptan benzoate.
The other ingredients of Rizatriptan tablets are mannitol, microcrystalline cellulose (E460a), crospovidone, aspartame (E951), magnesium stearate (E572), Colloidal Silicon Dioxide, peppermint flavor (contains modified food starch).
5 mg tablets are white to off white, approximately 7 mm round, flat, beveled edged uncoated tablets, engraved with ‘467’ on one side and plain on other side.
10 mg tablets are white to off white, approximately 9mm round, flat, beveled edged uncoated tablets, engraved with ‘468’ on one side and plain on other side
The tablets are packed in Aluminium/Aluminium blisters.
5 mg Pack sizes: Packs with 3, 6, or 18 tablets.
10 mg Pack sizes: Packs with 3, 6, 12 or 18 tablets.
Not all pack sizes may be marketed.
Rizatriptan is also available as an orodispersible tablet that dissolves in the mouth.
This leaflet was last revised in 07/2016.