Active ingredient
- olaparib
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet are: EU/1/14/959/002, EU/1/14/959/003, EU/1/14/959/004, EU/1/14/959/005.
Lynparza 100mg and 150mg film-coated tablets
Package leaflet: Information for the patient
Lynparza 100 mg film-coated tablets
Lynparza 150 mg film-coated tablets
olaparib
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
What is in this leaflet
1. What Lynparza is and what it is used for
2. What you need to know before you take Lynparza
3. How to take Lynparza
4. Possible side effects
5. How to store Lynparza
6. Contents of the pack and other information
1. What Lynparza is and what it is used for
What Lynparza is and how it works
Lynparza contains the active substance olaparib. Olaparib is a type of cancer medicine called a PARP inhibitor (poly [adenosine diphosphate-ribose] polymerase inhibitor).
PARP inhibitors can destroy cancer cells that are not good at repairing DNA damage. These specific cancer cells can be identified by:
What Lynparza is used for
Lynparza is used for the treatment of:
2. What you need to know before you take Lynparza
Do not take Lynparza:
Do not take Lynparza if any of the above apply to you. If you are not sure, talk to your doctor, pharmacist or nurse before taking Lynparza.
Warnings and precautions
Talk to your doctor, pharmacist or nurse before or during treatment with Lynparza:
If you think any of these may apply to you, talk to your doctor, pharmacist or nurse before or during treatment with Lynparza.
Tests and checks
Your doctor will check your blood before and during treatment with Lynparza.
You will have a blood test:
If your blood count falls to a low level, you may need to have a blood transfusion (where you are given new blood or blood-based products from a donor).
Other medicines and Lynparza
Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines. This includes medicines obtained without a prescription and herbal medicines. This is because Lynparza can affect the way some other medicines work. Also, some other medicines can affect the way Lynparza works.
Tell your doctor, pharmacist or nurse if you are taking or are planning to take any of the following medicines:
Tell your doctor, pharmacist or nurse if you are taking any of the above or any other medicines. The medicines listed here may not be the only ones that could affect Lynparza.
Lynparza with drink
Do not drink grapefruit juice while you are being treated with Lynparza. It can affect the way the medicine works.
Contraception, pregnancy and breast-feeding
Female patients:
Male patients:
Driving and using machines
Lynparza may influence your ability to drive and use machines. If you feel dizzy, weak or tired while taking Lynparza, do not drive or use tools or machines.
Information on other ingredients in this medicine
This medicine contains less than 1 mmol sodium (23 mg) per 100 mg or 150 mg tablet, that is to say essentially “sodium-free”.
3. How to take Lynparza
Your doctor has prescribed Lynparza film-coated tablets for you. Please note Lynparza is also available as a 50 mg capsule.
Always take this medicine exactly as your doctor, pharmacist or nurse has told you. Check with your doctor, pharmacist or nurse if you are not sure.
How to take
How much to take
Your doctor may prescribe a different dose if:
If you take more Lynparza than you should
If you take more Lynparza than your normal dose, contact your doctor or the nearest hospital straight away.
If you forget to take Lynparza
If you forget to take Lynparza, take your next normal dose at its scheduled time. Do not take a double dose (two doses at the same time) to make up for a forgotten dose.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Tell your doctor straight away if you notice any of the following:
Very common (may affect more than 1 in 10 people):
Uncommon (may affect up to 1 in 100 people):
Other side effects include:
Very common (may affect more than 1 in 10 people):
Very common side effects that may show up in blood tests:
Common (may affect up to 1 in 10 people):
Common side effects that may show up in blood tests:
Uncommon side effects that may show up in blood tests:
Your doctor will test your blood every month for the first year of treatment and at regular intervals after that. Your doctor will tell you if there are any changes in your blood test that might need treatment.
If you notice any side effects not listed in this leaflet, please contact your doctor straight away.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via (see details below). By reporting side effects you can help provide more information on the safety of this medicine.
or search for MHRA Yellow Card in the Google Play or Apple App Store
5. How to store Lynparza
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and the blister after EXP. The expiry date refers to the last day of that month.
This medicine does not require any special temperature storage conditions.
Store in the original package in order to protect from moisture.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. Contents of the pack and other information
What Lynparza contains
The active substance is olaparib.
The other ingredients (excipients) are:
See section 2 “Information on other ingredients in this medicine”.
What Lynparza looks like and contents of the pack
Lynparza 100 mg tablets are yellow to dark yellow, oval, bi-convex, film-coated tablets, marked with “OP100” on one side and plain on the other.
Lynparza 150 mg tablets are green to green/grey, oval, bi-convex, film-coated tablets, marked with “OP150” on one side and plain on the other.
Lynparza is supplied in packs containing 56 film-coated tablets (7 blisters of 8 tablets each), or multipacks containing 112 (2 packs of 56) film-coated tablets.
Not all pack sizes may be marketed.
Marketing Authorisation Holder
Manufacturer
For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder:
This leaflet was last revised in October 2019
Other sources of information
Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu.
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