Boots All-in-one Max Strength Cold & Flu Relief Powder for Oral Solution

Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist have told you.

• Keep this leaflet. You may need to read it again.
• Ask your pharmacist if you need more information or advice.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
• You must talk to a doctor if you do not feel better or if you feel worse after 3 days.

1. What this medicine is and what it is used for
2. What you need to know before you take this medicine
3. How to take this medicine
4. Possible side effects
5. How to store this medicine
6. Contents of the pack and other information

• paracetamol which is a pain reliever (analgesic) and helps reduce your temperature when you have a fever
• guaifenesin which is an expectorant to help loosen phlegm
• phenylephrine which is a decongestant to reduce swelling in the passages of the nose to help you breathe more easily.

These sachets are used for the relief of the symptoms of colds and flu and the pain and congestion of sinusitis, including aches and pains, headache, blocked nose and sore throat, chills and feverishness (high temperature). They can also loosen stubborn mucus (phlegm) and provide relief from chesty coughs.

• are allergic to paracetamol, guaifenesin, phenylephrine or any of the other ingredients (listed in section 6)
• have a serious heart condition or cardiovascular disorder(s)
• have high blood pressure (hypertension)
• have diabetes
• have an overactive thyroid
• have an enlarged prostate
• have glaucoma, including closed angle glaucoma
• have difficulty passing urine
• are taking antidepressant drugs called monoamine oxidase inhibitors (MAOI’s), or have taken them within the last 14 days - these are medicines such as phenelzine, isocarboxazid and tranylcypromine
• are taking beta-blocking drugs
• are currently taking other decongestant drugs (e.g. ephedrine and xylometazoline) or stimulants (e.g. dexamfetamine)
• are taking a cough medicine called a cough suppressant
• are taking tricyclic antidepressants such as imipramine, amitriptyline
• suffer from kidney or liver problems, including alcoholic liver disease
• have phaeochromocytoma.

Talk to your doctor or pharmacist before taking this medicine if you:

• are pregnant or breast-feeding
• have a very bad cough or asthma. See your doctor if your cough lasts for more than 5 days or comes back, or if you have a fever, rash or a headache which won’t go away
• have circulatory disorders such as a condition called Raynaud’s Phenomenon, which results from poor circulation in the fingers and toes
• have angina
• have severe stomach or intestinal problems
• have an intolerance to some sugars
• suffer with phenylketonuria, a rare, inherited metabolic disorder.

During treatment with this medicine, tell your doctor straight away if:

• you have severe illnesses, including severe renal impairment or sepsis (when bacteria and their toxins circulate in the blood leading to organ damage), or you suffer from malnutrition, chronic alcoholism or if you are also taking flucloxacillin (an antibiotic). A serious condition called metabolic acidosis (a blood and fluid abnormality) has been reported in patients in these situations when paracetamol is used at regular doses for a prolonged period or when paracetamol is taken together with flucloxacillin. Symptoms of metabolic acidosis may include: serious breathing difficulties with deep rapid breathing, drowsiness, feeling sick (nausea) and being sick (vomiting).

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines especially:

• medicines to treat high cholesterol levels which reduce the amount of fat in the blood such as colestyramine
• medicines to control feeling sick or being sick such as metoclopramide or domperidone
• medicines called anti-coagulants, which are used to thin the blood such as warfarin or other coumarins – you may take occasional doses of paracetamol but should consult your doctor if you need to take it on a regular basis
• barbiturates (for epilepsy or to help you sleep), such as phenobarbitone
• medicines to treat heart or circulatory problems, or to lower blood pressure, (e.g. digoxin, guanethidine, reserpine, methyldopa)
• medicines to treat migraine (e.g. ergotamine and methysergide)
• beta blockers (e.g. atenolol) or vasodilators (e.g. hydralazine)
• phenothiazines used as sedatives (e.g. chlorpromazine, pericyazine and fluphenazine)
• if you are going to have a general anaesthetic, as this may cause changes in heart rhythm
• flucloxacillin (antibiotic), due to a serious risk of blood and fluid abnormality (called metabolic acidosis) that must have urgent treatment (see section 2).

Contains paracetamol.

Do not take anything else containing paracetamol while taking this medicine.

Do not drink alcohol (beer, wine, spirits etc) while taking this product.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

• if you are taking medication, or are under medical care, consult your doctor before using this medicine
• long term use of this product is not recommended
• this medicine should only be used if you have all of the following symptoms - pain and/or fever, a blocked nose and a chesty cough
• use medicines which will only treat the symptoms you have
• do not take with other flu, cold or decongestant products
• this product could cause dizziness.
  If affected do not drive or operate machinery.

Contains 2 g sucrose (sugar) per sachet. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product. This should be taken into account in patients with diabetes. May be harmful to the teeth.

This medicine contains 30 mg aspartame (E951) in each sachet.

Aspartame is a source of phenylalanine. It may be harmful if you have phenylketonuria (PKU), a rare genetic disorder in which phenylalanine builds up because the body cannot remove it properly.

This medicine contains 117 mg sodium (main component of cooking/table salt) in each sachet. This is equivalent to 6% of the recommended maximum daily dietary intake of sodium for an adult.

1 sachet every 4 to 6 hours, as required. Do not take more than 4 sachets (4 doses) in any 24 hour period. Leave at least 4 to 6 hours between doses.

Do not give to children under 16 years.

Do not take more medicine than the label tells you to. If you do not get better, talk to your doctor.

Do not take for longer than 3 days, unless advised by your doctor.

Talk to a doctor at once if you take too much of this medicine even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage. Go to your nearest hospital casualty department. Take your medicine and this leaflet with you.

• allergic reactions with swelling of the mouth, lips, tongue, throat or face which may make it difficult to breathe (anaphylaxis, angioedema)
• severe skin reactions can include ulcers, blistering or peeling of the skin (Steven-Johnsons syndrome or toxic epidermal necrolysis)
• breathing problems and wheezing. These are more likely if you have experienced them before when taking other painkillers such as ibuprofen or aspirin
• unexplained bruising or bleeding (caused by low platelets in the blood)
• recurring fevers or infections (caused by low white blood cells which increases the likelihood of infections)
• severe stomach discomfort (caused by inflammation of the pancreas)
• liver problems, which may appear as jaundice (yellowing of the eyes and skin), nausea and abdominal pain (hepatic dysfunction)
• unusually fast pulse rate or a sensation of an unusually fast or irregular heartbeat (tachycardia, palpitations).

• difficulty passing water (the frequency is unknown but is more likely to occur in men with an enlarged prostate)
• less serious allergic reaction including rashes, dermatitis or urticaria (hives)
• headache, dizziness, insomnia (problems sleeping)
• nausea (feeling sick), vomiting, stomach discomfort, diarrhoea
• nervousness, irritability, restlessness, excitability
• increased blood pressure
• visual disturbances. This is rare but is more likely in those with glaucoma.

Frequency not known (frequency cannot be estimated from the available data):

A serious condition that can make blood more acidic (called metabolic acidosis), in patients with severe illness using paracetamol (see section 2).

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects, you can help provide more information on the safety of this medicine.

The active ingredients are paracetamol, guaifenesin and phenylephrine hydrochloride. Each 5.2 g sachet contains paracetamol 1000 mg, guaifenesin 200 mg and phenylephrine hydrochloride 12.2 mg.

The other ingredients are: sucrose, citric acid, tartaric acid, sodium citrate, acesulfame potassium (E950), aspartame (E951), powdered menthol flavour, lemon flavour and the colour quinoline yellow (E104).

Each 5.2 g sachet contains off white powder.

This pack contains 5 or 10 sachets. Not all pack sizes may be marketed.

Manufactured for

by the Marketing Authorisation holder