Adverse effects may include dry mouth, anxiety, restlessness, tremor, insomnia, tachycardia, cardiac arrhythmias, palpitations, hypertension, nausea, vomiting, headache and occasionally urinary retention in males and skin rashes. Hallucinations have been reported rarely, particularly in children.
Immune system disorders
Hypersensitivity reactions, including cross sensitivity that may occur with other sympathomimetics.
Skin and subcutaneous tissue disorders:
Frequency unknown: Severe skin reactions, including acute generalized exanthematous pustulosis (AGEP).
Gastrointestinal Disorders:
Nausea, vomiting, dry mouth
Frequency unknown: Ischaemic colitis
Eye disorders:
Frequency unknown: Ischaemic optic neuropathy
Nervous system disorders:
Headache, dizziness, tremor
Frequency unknown: Posterior reversible encephalopathy syndrome (PRES) (see section 4.4). Reversible cerebral vasoconstriction syndrome (RCVS) (see section 4.4)
Cardiac disorders:
Tachycardia, palpitations, cardiac arrhythmias
Renal and urinary disorders:
Urinary retention in males.
Vascular disorders:
Hypertension
Psychiatric disorders:
Sleep disturbance, insomnia, restlessness, anxiety, hallucinations (particularly in children).
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.