Active ingredient
- enoxaparin sodium
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PLGB 50701/0008.
Inhixa 2,000 IU (20 mg)/0.2 mL - 10,000 IU (100 mg)/1 mL solution for injection
Package leaflet: Information for the user
Inhixa 2,000 IU (20 mg)/0.2 mL solution for injection
Inhixa 4,000 IU (40 mg)/0.4 mL solution for injection
Inhixa 6,000 IU (60 mg)/0.6 mL solution for injection
Inhixa 8,000 IU (80 mg)/0.8 mL solution for injection
Inhixa 10,000 IU (100 mg)/1 mL solution for injection
enoxaparin sodium
Read all of this leaflet carefully before you start using this medicine because it contains important information for you.
What is in this leaflet
1. What Inhixa is and what it is used for
2. What you need to know before you use Inhixa
3. How to use Inhixa
4. Possible side effects
5. How to store Inhixa
6. Contents of the pack and other information
1. What Inhixa is and what it is used for
Inhixa contains the active substance called enoxaparin sodium that is a low molecular weight heparin (LMWH).
Inhixa works in two ways:
1) Stopping existing blood clots from getting bigger. This helps your body to break them down and stop them causing you harm.
2) Stopping blood clots forming in your blood.
Inhixa can be used to:
2. What you need to know before you use Inhixa
Do not use Inhixa
Warnings and precautions
Inhixa should not be used interchangeably with other medicines belonging to the group of low molecular weight heparins. This is because they are not exactly the same and do not have the same activity and instructions for use.
Talk to your doctor or pharmacist before using Inhixa if:
You may have a blood test before you start using this medicine and at intervals while you are using it; this is to check the level of the clotting cells (platelets) and potassium in your blood.
Children and adolescents
The safety and efficacy of Inhixa has not been evaluated in children or adolescents.
Other medicines and Inhixa
Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines.
Operations and anaesthetics
If you are going to have a spinal puncture or an operation where an epidural or spinal anaesthetic is used, tell your doctor that you are using Inhixa. See “Do not use Inhixa”. Also, tell your doctor if you have any problem with your spine or if you ever had spinal surgery.
Pregnancy and breast-feeding
If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
If you are pregnant and have a mechanical heart valve, you may be at an increased risk of developing blood clots. Your doctor should discuss this with you.
If you are breast-feeding or plan to breast-feed, you should ask your doctor for advice before taking this medicine.
Driving and using machines
Inhixa does not affect the ability to drive and operate machinery.
Traceability
It is important to keep a record of the batch number of your Inhixa. So, every time you get a new package of Inhixa, note down the date and the batch number (which is on the packaging after Lot) and keep this information in a safe place.
Inhixa contains sodium
This medicine contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially 'sodium-free'.
3. How to use Inhixa
Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
Having this medicine
Do not inject Inhixa into a muscle.
How much will be given to you
1. Treating blood clots that are in your blood
2. Stopping blood clots forming in your blood in the following situations:
Inhixa can be used for two different types of heart attack called STEMI (ST segment elevation myocardial infarction) or non-STEMI (NSTEMI).
The amount of Inhixa given to you will depend on your age and the kind of heart attack you have had.
NSTEMI type of heart attack:
STEMI type of heart attack if you are under 75 years old:
STEMI type of heart attack if you are 75 years old or older:
For patients having a procedure called percutaneous coronary intervention (PCI):
Depending on when you were last given Inhixa, your doctor may decide to give an additional dose of Inhixa before the PCI procedure. This is by injection into your vein.
3. Stopping blood clots from forming in the tubes of your dialysis machine
How to give yourself an injection of Inhixa with a pre-filled syringe with needle guard
Your pre-filled syringe has a needle guard attached to it in order to protect you from needle stick injury.
If you are able to give this medicine to yourself, your doctor or nurse will show you how to do this. Do not try to inject yourself if you have not been trained to do so. If you are not sure what to do, talk to your doctor or nurse immediately.
Before injecting yourself with Inhixa
Instructions on injecting yourself with Inhixa
1) Wash your hands and the area that you will inject with soap and water. Dry them.
2) Sit or lie in a comfortable position so you are relaxed. Make sure you can see the place you are going to inject. In a lounge chair, recliner, or propped up in bed with pillows is ideal.
3) Choose an area on the right or left side of your stomach. This should be at least 5 cm away from your belly button and out towards your sides.
Remember: Do not inject yourself within 5 cm of your belly button or around existing scars or bruises. Change the place where you inject between the left and right sides of your stomach, depending on the area you were last injected.
4) Remove the plastic blister containing the pre-filled syringe from the box. Open the blister and remove the pre-filled syringe.
5) Carefully pull off the needle cap from the syringe. Throw away the cap. The syringe is pre-filled and ready to use.
Do not press on the plunger before injecting yourself. Once you have removed the cap, do not allow the needle to touch anything. This is to make sure the needle stays clean (sterile).
6) Hold the syringe in the hand you write with (like a pencil) and with your other hand, gently pinch the cleaned area of your abdomen between your forefinger and thumb to make a fold in the skin.
Make sure you hold the skin fold throughout the injection.
7) Hold the syringe so that the needle is pointing downwards (vertically at a 90 º angle). Insert the full length of the needle into the skin fold.
8) Press down on the plunger with your thumb. This will inject the medicine into the fatty tissue of the abdomen. Make sure you hold the skin fold throughout the injection.
9) Remove the needle by pulling it straight out. Do not release the pressure on the plunger!
To avoid bruising, do not rub the injection site after you have injected yourself.
10) Push hard the plunger. The needle guard, which is in the form of a plastic cylinder, will be activated automatically and it will completely cover the needle.
11) Drop the used syringe into the sharps container. Close the container lid tightly and place the container out of reach of children.
When the container is full, dispose of it as your doctor or pharmacist has instructed. Do not put it in the household rubbish.
Changing anticoagulant treatment
If you use more Inhixa than you should
If you think that you have used too much or too little Inhixa, tell your doctor, nurse or pharmacist immediately, even if you have no signs of a problem. If a child accidentally injects or swallows Inhixa, take the child to a hospital casualty department straight away.
If you forget to use Inhixa
If you forget to give yourself a dose, have it as soon as you remember. Do not give yourself a double dose on the same day to make up for a forgotten dose. Keeping a diary will help to make sure you do not miss a dose.
If you stop using Inhixa
If you have any further questions on the use of this medicine, ask your doctor or pharmacist or nurse.
It is important for you to keep having Inhixa injections until your doctor decides to stop them. If you stop, you could get a blood clot which can be very dangerous.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Like other anticoagulant medicines (medicines to reduce blood clotting), Inhixa may cause bleeding which may potentially be life-threatening. In some cases the bleeding may not be obvious.
If you experience any bleeding that does not stop by itself or if you experience signs of excessive bleeding (exceptional weakness, tiredness, paleness, dizziness, headache or unexplained swelling), consult your doctor immediately.
Your doctor may decide to keep you under closer observation or change your medicine.
Stop using Inhixa and talk to a doctor or nurse at once if you get any signs of a severe allergic reaction (such as difficulty breathing, swelling of the lips, mouth, throat or eyes).
Stop using Inhixa and seek medical attention immediately if you notice any of the following symptoms:
A red, scaly widespread rash with bumps under the skin and blisters accompanied by fever. The symptoms usually appear at the initiation of treatment (acute generalised exanthematous pustulosis).
You should tell your doctor straight away
Your doctor may ask you to have performed a blood test to check your platelet count.
Overall list of possible side effects:
Very common (may affect more than 1 in 10 people)
Common (may affect up to 1 in 10 people)
Uncommon (may affect up to 1 in 100 people)
Rare (may affect up to 1 in 1,000 people)
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Inhixa
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the label and carton. The expiry date refers to the last day of that month.
Store below 25 °C. Do not freeze.
After dilution the solution should be used within 8 hours.
Do not use this medicine if you notice any visible change in the appearance of the solution.
The Inhixa pre-filled syringes are for single dose use only. Discard any unused medicine.
Do not throw away any medicines via wastewater or household waste.
Ask your pharmacist how to throw away medicines you no longer use.
These measures will help protect the environment.
6. Contents of the pack and other information
What Inhixa contains
What Inhixa looks like and contents of the pack
Inhixa 2,000 IU (20 mg)/0.2 mL is 0.2 mL of solution in:
Supplied in packs of:
Inhixa 4,000 IU (40 mg)/0.4 mL is 0.4 mL of solution in:
Supplied in packs of:
Inhixa 6,000 IU (60 mg)/0.6 mL is 0.6 mL of solution in:
Supplied in packs of:
Inhixa 8,000 IU (80 mg)/0.8 mL is 0.8 mL of solution in:
Supplied in packs of:
Inhixa 10,000 IU (100 mg)/1 mL is 1 mL of solution in:
Supplied in packs of:
Not all pack sizes may be marketed.
Marketing Authorisation Holder
Manufacturer
For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder:
This leaflet was last revised in March 2022
Other sources of information
Detailed information on this medicine is available on the Medicines and Healthcare products Regulatory Agency web site: https://www.gov.uk/government/organisations/medicines-andhealthcare-products-regulatory-agency
20220301-01
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August 2017
01271 334 609
01271 334 609