- adrenaline acid tartrate
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 02848/5909.
Adrenaline (Epinephrine) 1:1,000 Solution for Injection
PACKAGE LEAFLET: INFORMATION FOR THE PATIENT
Adrenaline (Epinephrine) 1:1,000 Solution for Injection
Read all of this leaflet carefully before you are given this medicine because it contains important information for you.
The name of your medicine is Adrenaline (Epinephrine) 1:1,000 Solution for Injection.
It will be referred to as Adrenaline Injection for ease hereafter.
What is in this leaflet
1. What Adrenaline Injection is and what it is used for
2. What you need to know before you are given Adrenaline Injection
3. How Adrenaline Injection will be given to you
4. Possible side effects
5. How to store Adrenaline Injection
6. Contents of the pack and other information
1. WHAT ADRENALINE INJECTION IS AND WHAT IT IS USED FOR
Adrenaline belongs to a class of drugs called sympathomimetic agents. Adrenaline Injection may be used to rapidly relieve severe allergic reactions to drugs or other substances causing allergy. It may also be used in the emergency treatment of shock due to a severe allergic reaction.
2. WHAT YOU NEED TO KNOW BEFORE YOU ARE GIVEN ADRENALINE INJECTION
You should not be given Adrenaline Injection:
Adrenaline injection should not be used in areas such as fingers, toes, ears, nose or penis, as the blood supply to these areas might become inadequate.
Warnings and precaution
Talk to your doctor or nurse before you are given Adrenaline Injection if:
Other medicines and Adrenaline Injection
Tell your doctor or pharmacist if you are taking, or recently taken or might take any other medicines.
A large number of drugs can interact with Adrenaline Injection which can significantly alter their effects.
These drugs include:
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.
Adrenaline should only be used during pregnancy and breast-feeding if considered essential by your doctor.
Driving and using machines
You should not drive or use machinery if you are affected by the administration of Adrenaline Injection.
Adrenaline Injection contains sodium metabisulphite
This medicine contains sodium metabisulphite, a preservative. This may rarely cause severe allergic (hypersensitivity) reactions and wheezing. This medicinal product contains less than 1mmol sodium (23mg) per dose (essentially ‘sodium-free’).
3. HOW ADRENALINE INJECTION WILL BE GIVEN TO YOU
The recommended dose is 500 micrograms (0.5ml of adrenaline 1/1000). If necessary, this dose may be repeated several times at 5-minute intervals.
Adrenaline may be injected either into a muscle or into the tissue just beneath the skin. It will be administered by a trained healthcare professional. Your doctor will decide the most suitable dosage for your particular case according to your age and physical circumstances.
Use in Children
The following doses of adrenaline 1/1,000 are recommended:
Over 12 years 0.5 mg IM (0.5ml 1:1000 solution)
6 - 12 years 0.3 mg IM (0.3ml 1:1000 solution)
6 months - 6 years 0.15 mg IM (0.15ml 1:1000 solution)
Under 6 months 0.01mg/kg IM (0.01ml/kg 1:1000 solution)
If necessary, these doses may be repeated at 5-15 -minute intervals according to blood pressure, pulse and respiratory function.
A small volume syringe should be used.
If you have any further questions on the use of this product, ask your doctor or nurse.
4. POSSIBLE SIDE EFFECTS
Like all medicines, this medicine can cause side effects, although not everyone gets them.
If you experience any of these following side effects, stop taking this medicine and report to a doctor immediately:
Other side effects
Not known: frequency cannot be estimated from the available data:
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store .
By reporting side effects you can help provide more information on the safety of this medicine.
5. HOW TO STORE ADRENALINE INJECTION
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and ampoule label after “Exp”. The expiry date refers to the last day of that month.
Do not store above 25°C.
Keep the container in the outer carton in order to protect from light.
The solution should not be used if it is discoloured in any way.
This medicine should not be mixed with any other drugs.
The solution must not be stored in contact with metals e.g. needles or metal parts of syringes, as dissolved metal ions may cause swelling at the site of the injection.
If only part of an ampoule is used, the remaining solution should be discarded.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. CONTENTS OF THE PACK AND OTHER INFORMATION
What Adrenaline Injection contains
The active substance is adrenaline. Each 1ml contains 1mg adrenaline (epinephrine) as the acid tartrate.
The other ingredients are sodium metabisulphite (E223), sodium chloride, sodium hydroxide or hydrochloric acid in water for injections.
What Adrenaline Injection looks like and contents of pack
Adrenaline Injection is a clear colourless, aqueous, sterile solution for injection, available in 1ml glass ampoules, packed in boxes containing 10 ampoules.
Marketing authorization Holder
This leaflet was last revised in November 2018.
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