The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 29831/0032.
Ceftazidime 1g, 2g, Powder for Solution for Injection or Infusion
Ceftazidime 1g powder for solution for injection or infusion
Ceftazidime 2g powder for solution for injection or infusion
The name of the medicine is ceftazidime 1g powder for solution for injection or infusion and ceftazidime 2g powder for solution for injection or infusion. In the rest of this leaflet it is called ceftazidime.
1. What ceftazidime is and what it is used for
2. What you need to know before you are given ceftazidime
3. How ceftazidime is given
4. Possible side effects
5. How to store ceftazidime
6. Contents of the pack and other information
Ceftazidime is an antibiotic used in adults and children (including newborn babies). It works by killing bacteria that cause infections. It belongs to a group of medicines called cephalosporins.
Ceftazidime can also be used:
Talk to your doctor, pharmacist or nurse before you start on ceftazidime
Take special care with ceftazidime
You must look out for certain symptoms such as allergic reactions, nervous system disorders and gastrointestinal disorders such as diarrhoea while you are being given ceftazidime.
This will reduce the risk of possible problems. See (‘Conditions you need to look out for’) in section 4. If you have had an allergic reaction to other antibiotics you may also be allergic to ceftazidime.
Ceftazidime can affect the results of urine tests for sugar and a blood test known as Coombs test. If you are having tests:
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
This includes medicines you can obtain without a prescription.
You shouldn’t be given ceftazidime without talking to your doctor if you are also taking:
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
Your doctor will consider the benefit of treating you with ceftazidime against the risk to your baby.
Ceftazidime can cause side effects that affect your ability to drive, such as dizziness. Don’t drive or use machines unless you are sure you’re not affected.
Ceftazidime contains sodium
This medicine contains 52mg sodium (main component of cooking/table salt) in each 1g vial. This is equivalent to 2.6% of the recommended maximum daily dietary intake of sodium for an adult.
This medicine contains 104mg sodium (main component of cooking/table salt) in each 2g vial. This is equivalent to 5.2% of the recommended maximum daily dietary intake of sodium for an adult.
Ceftazidime is usually given by a doctor or nurse. It can be given as a drip (intravenous infusion) or as an injection directly into a vein or into a muscle.
Ceftazidime is made up by the doctor, pharmacist or nurse using water for injections or a suitable infusion fluid.
The correct dose of ceftazidime for you will be decided by your doctor and depends on: the severity and type of infection, whether you are on any other antibiotics; your weight and age, how well your kidneys are working.
Newborn babies (0-2 months)
For every 1kg the baby weighs, they’ll be given 25 to 60mg ceftazidime per day divided in two doses.
Babies (over 2 months) and children who weigh less than 40kg
For every 1kg the baby or child weighs, they’ll be given 100 to 150mg of ceftazidime per day divided in three doses. Maximum 6g per day.
Adults and adolescents who weigh 40kg or more
1 to 2g of ceftazidime three times daily. Maximum of 9g per day.
Patients over 65
The daily dose should not normally exceed 3g per day, especially if you are over 80 years of age.
Patients with kidney problems
You may be given a different dose to the usual dose. The doctor or nurse will decide how much ceftazidime you will need, depending on the severity of the kidney disease. Your doctor will check you closely and you may have more regular kidney function tests.
If you accidentally use more than your prescribed dose, contact your doctor or nearest hospital straight away.
If you miss an injection, you should have it as soon as possible. However, if it is almost time for your next injection, skip the missed injection. Do not take a double dose (two injections at the same time) to make up for a forgotten dose.
Don’t stop taking ceftazidime unless your doctor tells you to. If you have any questions on the use of this medicine, ask your doctor or nurse.
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following serious side effects have occurred in a small number of people but their exact frequency is unknown:
There have been rare reports of severe hypersensitivity reactions with severe rash, which may be accompanied by fever, fatigue, swelling of the face or lymph glands, increase of eosinophils (type of white blood cells), effects on liver, kidney or lung (a reaction called DRESS).
Common side effects
These may affect up to 1 in 10 people:
Common side effects that may show up in blood tests:
Uncommon side effects
These may affect up to 1 in 100 people:
Uncommon side effects that may show up in blood tests:
Very rare side effects
These may affect up to 1 in 10,000 people:
Other side effects have occurred in a small number of people but their exact frequency is unknown:
Other side effects that may show up in blood tests:
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting systems listed below.
or search for MHRA Yellow Card in the Google Play or Apple App Store
By reporting side effects you can help provide more information on the safety of this medicine.
Keep this medicine out of the sight and reach of children
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
The active substance is ceftazidime as ceftazidime pentahydrate.
Each vial contains the equivalent of 1g or 2g of ceftazidime. It also contains the ingredient, sodium carbonate.
The sodium content per vial is approximately 52mg (2.26 mmol) for the 1g vial and 104mg (4.52 mmol) for the 2g vial.
Ceftazidime is a white to cream coloured powder, which must be made into a solution before injection or infusion. It is available in packs of 1, 5 or 10 vials. Not all pack sizes are marketed.
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Ceftazidime 1g powder for solution for injection or infusion 29831/0031
Ceftazidime 2g powder for solution for injection or infusion 29831/0032
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This leaflet was last revised in 07/2021