Active ingredient
- ticagrelor
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet are: EU/1/10/655/003, EU/1/10/655/005, EU/1/10/655/002, EU/1/10/655/001, EU/1/10/655/006, EU/1/10/655/004.
Brilique 90 mg film coated tablets
Package leaflet: Information for the user
Brilique 90 mg film-coated tablets
ticagrelor
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
What is in this leaflet
1. What Brilique is and what it is used for
2. What you need to know before you take Brilique
3. How to take Brilique
4. Possible side effects
5. How to store Brilique
6. Contents of the pack and other information
1. What Brilique is and what it is used for
What Brilique is
Brilique contains an active substance called ticagrelor. This belongs to a group of medicines called antiplatelet medicines.
What Brilique is used for
Brilique in combination with acetylsalicylic acid (another antiplatelet agent) is to be used in adults only. You have been given this medicine because you have had:
It reduces the chances of you having another heart attack, stroke or dying from a disease related to your heart or blood vessels.
How Brilique works
Brilique affects cells called ‘platelets’ (also called thrombocytes). These very small blood cells help stop bleeding by clumping together to plug tiny holes in blood vessels that are cut or damaged.
However, platelets can also form clots inside diseased blood vessels in the heart and brain. This can be very dangerous because:
Brilique helps stop the clumping of platelets. This reduces the chance of a blood clot forming that can reduce blood flow.
2. What you need to know before you take Brilique
Do not take Brilique if:
Do not take Brilique if any of the above applies to you. If you are not sure, talk to your doctor or pharmacist before taking this medicine.
Warnings and precautions
Talk to your doctor or pharmacist before taking Brilique if:
If any of the above apply to you (or you are not sure), talk to your doctor or pharmacist before taking this medicine.
If you are taking both Brilique and heparin:
Children and adolescents
Brilique is not recommended for children and adolescents under 18 years.
Other medicines and Brilique
Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is because Brilique can affect the way some medicines work and some medicines can have an effect on Brilique.
Tell your doctor or pharmacist if you are taking any of the following medicines:
In particular, tell your doctor or pharmacist if you are taking any of the following medicines that increase your risk of bleeding:
Also tell your doctor that because you are taking Brilique, you may have an increased risk of bleeding if your doctor gives you fibrinolytics, often called ‘clot dissolvers’, such as streptokinase or alteplase.
Pregnancy and breast-feeding
It is not recommended to use Brilique if you are pregnant or may become pregnant. Women should use appropriate contraceptive measures to avoid pregnancy while taking this medicine.
Talk to your doctor before taking this medicine if you are breast-feeding. Your doctor will discuss with you the benefits and risks of taking Brilique during this time.
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Driving and using machines
Brilique is not likely to affect your ability to drive or use machines. If you feel dizzy or confused while taking this medicine, be careful while driving or using machines.
Sodium content
This medicine contains less than 1 mmol sodium (23 mg) per dose, that is to say it is essentially ‘sodium-free’.
3. How to take Brilique
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
How much to take
Taking Brilique with other medicines for blood clotting
Your doctor will usually also tell you to take acetylsalicylic acid. This is a substance present in many medicines used to prevent blood clotting. Your doctor will tell you how much to take (usually between 75-150 mg daily).
How to take Brilique
If you have trouble swallowing the tablet
If you have trouble swallowing the tablet you can crush it and mix with water as follows:
If you are in the hospital you may be given this tablet mixed with some water and given through a tube via the nose (nasogastric tube).
If you take more Brilique than you should
If you take more Brilique than you should, talk to a doctor or go to hospital straight away. Take the medicine pack with you. You may be at increased risk of bleeding.
If you forget to take Brilique
If you stop taking Brilique
Do not stop taking Brilique without talking to your doctor. Take this medicine on a regular basis and for as long as your doctor keeps prescribing it. If you stop taking Brilique, it may increase your chances of having another heart attack or stroke or dying from a disease related to your heart or blood vessels.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with this medicine:
Brilique affects blood clotting, so most side effects are related to bleeding. Bleeding may occur in any part of the body. Some bleeding is common (like bruising and nosebleeds). Severe bleeding is uncommon but can be life threatening.
See a doctor straight away if you notice any of the following – you may need urgent medical treatment:
Discuss with your doctor if you notice any of the following:
Other possible side effects
Very common (may affect more than 1 in 10 people)
Common (may affect up to 1 in 10 people)
Uncommon (may affect up to 1 in 100 people)
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Brilique
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the blister and carton after EXP. The expiry date refers to the last day of that month.
This medicine does not require any special storage conditions.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.
6. Contents of the pack and other information
What Brilique contains
What Brilique looks like and contents of the pack
Film-coated tablet (tablet): The tablets are round, biconvex, yellow, film-coated marked with a “90” above “T” on one side.
Brilique is available in:
Not all pack sizes may be marketed.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder:
Manufacturer:
Manufacturer:
For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder:
This leaflet was last revised in September 2019.
Other sources of information
Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu.
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