Active ingredient
- bicalutamide
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 17901/0005.
Casodex 50 mg Film-coated Tablets
Package leaflet: Information for the user
Casodex 50 mg Film-coated Tablets
Bicalutamide
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
What is in this leaflet:
1. What Casodex is and what it is used for
2. What you need to know before you take Casodex
3. How to take Casodex
4. Possible side effects
5. How to store Casodex
6. Contents of the pack and other information
1. What Casodex is and what it is used for
Casodex contains a medicine called bicalutamide. This belongs to a group of medicines called ‘anti-androgens’.
2. What you need to know before you take Casodex
Do not take Casodex:
Do not take Casodex if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Casodex.
Casodex must not be given to children.
Warnings and precautions
Talk to your doctor or pharmacist before taking Casodex:
Other medicines and Casodex
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes medicines obtained without a prescription and herbal medicines. This is because Casodex can affect the way other medicines work. Also some other medicines can affect the way Casodex works.
Do not take Casodex if you are already taking any of the following medicines:
Casodex might interfere with some medicines used to treat heart rhythm problems (e.g. quinidine, procainamide, amiodarone and sotalol) or might increase the risk of heart rhythm problems when used with some other drugs [e.g. methadone (used for pain relief and part of drug addiction detoxification), moxifloxacin (an antibiotic)], antipsychotics used for serious mental illnesses.
Also, tell your doctor or pharmacist if you are taking any of the following medicines:
Pregnancy, breast-feeding and fertility
Casodex must not be taken by women, including pregnant women or mothers who are breast-feeding their babies.
Casodex may have an effect on male fertility which could be reversible.
Driving and using machines
Casodex is not likely to affect you being able to drive or use any tools or machines.
However, if you feel sleepy take care with these activities.
Casodex contains lactose
Lactose is a type of sugar. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Casodex contains sodium
This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodium-free’.
3. How to take Casodex
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
If you take more Casodex than you should
If you take more Casodex than prescribed by your doctor, talk to a doctor or go to a hospital straight away.
If you forget to take Casodex
If you have any further questions on the use of this medicine, ask your doctor or pharmacist or nurse.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Allergic reactions
These are uncommon (may affect up to 1 in 100 people):
The symptoms can include sudden onset of:
If this happens to you, see a doctor straight away.
Also tell your doctor straight away if you notice any of the following:
Very common (may affect more than 1 in 10 people):
Common (may affect up to 1 in 10 people):
Uncommon (may affect up to 1 in 100 people):
Not known (frequency cannot be estimated from the available data):
Other possible side effects:
Very common (may affect more than 1 in 10 people)
Common (may affect up to 1 in 10 people)
Rare (may affect up to 1 in 1,000 people)
Your doctor may do blood tests to check for any changes to your blood.
Do not be concerned by this list of possible side effects. You may not get any of them.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Casodex
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. Contents of the pack and other information
What Casodex 50 mg Film-coated Tablets contains
The active substance is bicalutamide. Each tablet contains 50 mg of bicalutamide.
The other ingredients are lactose monohydrate (see section 2, Casodex contains lactose), magnesium stearate, hypromellose, macrogol 300, povidone, sodium starch glycolate and titanium dioxide (E171).
What Casodex 50 mg Film-coated Tablets look like and contents of the pack
Casodex 50 mg Film-coated Tablets are white and come in packs of 28 tablets.
Marketing Authorisation Holder and Manufacturer
The Marketing Authorisation for Casodex 50 mg Film-coated Tablets is held by
Casodex 50 mg Film-coated Tablets are manufactured by
To listen to or request a copy of this leaflet in Braille, large print or audio please call, free of charge:
0800 198 5000 (UK only)
Please be ready to give the following information:
Product name Casodex 50 mg Film-coated Tablets
Reference number 17901/0005
This is a service provided by the Royal National Institute of Blind People.
This leaflet was last revised in April 2020.
© AstraZeneca 2020
Casodex is a trade mark of the AstraZeneca group of companies.
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