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Adenosine 3mg/ml (6mg in 2ml) Solution for Injection
Adenosine 3mg/ml Solution for Injection (6mg in 2ml)
(Referred to as Adenosine Injection in the remainder of the leaflet)
1. What Adenosine Injection is and what it is used for
2. What you need to know before you are given Adenosine Injection
3. How you will be given Adenosine Injection
4. Possible side effects
5. How to store Adenosine Injection
6. Contents of the pack and other information
The name of your medicine is Adenosine Injection. The active ingredient in your medicine is adenosine. Adenosine belongs to a group of medicines called antiarrhythmics.
Adenosine Injection works by slowing down electrical impulse between the upper and lower chambers of the heart. This slows the fast or uneven heartbeat called arrhythmias.
Adenosine Injection is used:
In children, Adenosine Injection bolus is used:
Do not have this medicine if any of the above apply to you. If you are not sure, talk to your doctor or nurse before you are given Adenosine.
Talk to your doctor, nurse, pharmacist before you have taken Adenosine if:
If you get a very slow heartbeat (severe bradycardia), respiratory failure, a heart problem that can be fatal (asystole), severe chest pains (angina) or very low blood pressure (severe hypotension), then treatment with Adenosine should be stopped.
If you are not sure if any of the above applies to you, talk to your doctor or nurse before being given Adenosine Injection.
Talk to your doctor immediately if:
In children with a heart rhythm trouble called ‘Wolff-Parkinson-White (WPW) syndrome’, Adenosine Injection may cause some unexpected severely abnormal heart rhythm.
Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. The following medicines can affect or be affected by treatment with Adenosine Injection:
Food and drink containing xanthines, for example tea, coffee, chocolate and cola, should be avoided for at least 12 hours before you are given Adenosine Injection.
Talk to your doctor or nurse before having this medicine if:
Ask your doctor or nurse for advice before taking any medicine.
This medicinal product contains approximately 7mg sodium per vial (2ml) i.e. essentially ‘sodium-free’.
Adenosine Injection is a medicine for use in hospitals with resuscitation equipment available.
Adenosine Injection will be given to you by a doctor or nurse as an injection. The injection will be into one of your veins. Your heart rate and blood pressure will be closely monitored.
The first dose is 3mg given over 2 seconds. This is given as a rapid injection into your vein. If the first dose does not bring your heartbeat to normal then you will be given a second dose. The second dose will be 6mg given as a rapid injection.
If the second dose does not bring your heart rate to normal then you will be given a third dose. The third dose is 12mg given as a rapid injection.
You will not be given any more doses after the 12mg dose.
Your doctor will decide if this medicine is needed, how much should be given depending on your child’s weight, and if several injections are needed.
This medicine is given to you by your doctor or nurse. It is unlikely that you will be given too much. You doctor will carefully work out how much Adenosine Injection you should be given.
If you have more of this medicine than you should, the following effects may happen:
Your doctor will be monitoring your heart throughout the procedure.
The length of time Adenosine stays in the blood is very short.
Any side effects of too much Adenosine Injection would quickly stop when the injection is stopped. You may be given an injection of a medicine called theophylline to help with any side effects.
If you have any further questions on the use of this product, ask your doctor or nurse.
Like all medicines, Adenosine Injection can cause side effects, although not everybody gets them. The following side effects may be experienced when taking Adenosine Injection.
If any of the side effects get worse, tell your doctor or nurse and they may stop the injection: The side effects normally settle within seconds or minutes after the injection is finished but you should tell your doctor or nurse if any of them happen.
Very common (affects more than 1 person in 10)
Common (affects less than 1 person in 10)
Uncommon (affects less than 1 person in 100)
Very rare side effects (affects less than 1 person in every 10,000)
Frequency not known:
If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or nurse.
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, website: www.mhra.gov.uk/yellowcard or search for the MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side effects you can help provide more information on the safety of this medicine
This medicine will be kept by your doctor or nurse in a safe place where children cannot see or reach it.
Do not use this medicine after the expiry date which is stated on the label and carton after EXP. The expiry date refers to the last day of that month.
Store below 25°C. Do not refrigerate.
The product should be used immediately after opening. Any portion of the vial not used at once should be disposed of.
Do not use if any particles or discolouration are noticed in the solution. If the appearance of the vial has changed the vial must be thrown away.
Medicines should not be disposed of via wastewater or household waste. Your doctor or nurse will dispose of any unused medicine.
These measures will help protect the environment.
The active ingredient is adenosine.
Each 2ml vial contains 6mg of adenosine.
The other ingredients are sodium chloride and water for injections.
Adenosine is a clear, colourless solution for injection.
Adenosine 3mg/ml (6mg in 2ml) Solution for Injection is available in packs of 6 single use glass vials.
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Adenosine 3mg/ml (6mg in 2ml) Solution for Injection PL 29831/0457
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This leaflet was last revised in 06/2023