The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 12762/0162.
Argipressin 20 IU/ml Solution for Injection
Argipressin 20 International Units/ml Solution for Injection
This product is known by the above name but will be referred to as Argipressin Injection throughout the rest of this leaflet.
1. What Argipressin Injection is and what it is used for
2. What you need to know before you are given Argipressin Injection
3. How Argipressin Injection will be given to you
4. Possible side effects
5. How to store Argipressin Injection
6. Contents of the pack and other information
Argipressin Injection contains argipressin which is similar to a naturally occurring hormone in your body. It is an 'antidiuretic' which helps to prevent excess loss of water in your urine and also narrows some blood vessels in the body.
Argipressin is used to treat:
You should not be given Argipressin Injection:
Speak to your doctor if one of these applies to you before you are given this medicine.
Talk to your doctor or nurse before you are given Argipressin Injection:
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
This is extremely important because some medicines can strengthen or weaken the effects of others.
In particular, tell your doctor if you are taking any of the following:
Do not drink alcohol before you are given Argipressin Injection.
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor, pharmacist or nurse before you are given this medicine. As with all drugs, Argipressin should only be given in pregnancy and when breast-feeding if absolutely necessary. Your doctor will guide you.
Argipressin can affect your ability to drive and use machinery safely, as you may feel dizzy after receiving your injection. Speak to your doctor for further advice.
It is most likely that you will be in hospital when you are given Argipressin.
The recommended dose is
For the treatment of diabetes insipidus: Injected under the skin or into a muscle every four hours. Your doctor will decide on the most suitable dose and way to give it to you depending on your symptoms.
For the treatment of bleeding in the oesophagus: The dose is diluted in a sugar solution and slowly dripped through a needle into a vein. Your doctor will decide on the most suitable dose and way to give it to you depending on your symptoms.
Argipressin is not recommended in children below 18 years
No dose change, give as per adults.
As the Injection will be administered by a doctor, it is unlikely that you will be given more than is necessary. However, if you think that you have been given too much, tell your doctor immediately. If you experience chest pain after receiving this medicine, inform your doctor immediately.
If you have any further questions on the use of this product, ask your doctor or nurse.
Like all medicines, this medicine can sometimes cause side effects, although not everyone gets them.
All medicines can cause allergic reactions although serious allergic reactions are rare. Any sudden wheeziness, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) should be reported to a doctor immediately as this can also result in a heart attack if not treated straight away.
Argipressin can cause 'water intoxication'. Signs of this are drowsiness, being uninterested in anything (listless) and headaches. If you notice any of these signs, tell the nurse or your doctor straightaway. If it is not corrected, water intoxication can lead to fits or even coma.
Other side effects include:
Not known: frequency cannot be estimated from the available data
In patients with disease of the heart or circulation, Argipressin may give rise to angina (chest pain).
If you get any side effects talk to your doctor or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side effects you can help provide more information on the safety of this medicine.
Keep this medicine out of the sight and reach of children.
The storage of Argipressin Injection will not be your responsibility.
Store in a refrigerator (2°C and 8°C). Keep the ampoules in the outer carton in order to protect from light. Do not freeze.
For single use only.
If only part used, discard the remaining solution.
Do not use this medicine after the expiry date which is stated on the label and carton. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Argipressin Injection is a clear, sterile solution. It is a solution for injection which comes in a small glass bottle (ampoule), containing 20 international units of the active ingredient, argipressin. Each ampoule has a blue OPC (one-point-cut) where the ampoule is opened and two (yellow and blue) product identification rings. It is available in packs of ten 1ml ampoules.
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This leaflet was last revised in September 2023.