This information is intended for use by health professionals
Glycerol 4g Suppositories
Each suppository contains 2800mg Glycerol
For full list of excipients , see 6.1.
Amber coloured suppository, of nominal weight 4g intended for rectal administration.
For occasional use as a stimulant laxative for the treatment of constipation.
For rectal use.
Adults and the elderly
One 4g suppository, to aid insertion the suppository tip should be moistened with water before use. No reduction in adult dosage is necessary for elderly patients.
Infants and Children
• Hypersensitivity to the active substance or to any of the excipients.
• The product is contraindicated if there is intestinal obstruction or blockage.
The product is intended for occasional use only. Prolonged or excessive use of the product is not recommended as this may cause diarrhoea. Use of this product may interfere with glucose control in diabetic patients. If symptoms persist consult a doctor.
No evidence of harmful affects available. However, best avoided during the first trimester of pregnancy. May be used during breast feeding.
Use of the product may occasionally cause abdominal cramps. Glycerol can cause irritation when given rectally.
Overdosage via rectal route is unlikely. However, if ingested treat symptomatically.
ATC code A06AX01
Glycerol is commonly classified as an osmotic laxative but may act additionally or alternatively by promoting peristalsis and evacuation of the lower bowel by virtue of a mild irritant effect. Glycerol suppositories possess also lubricating and faecal softening actions.
Glycerol following rectal administration is poorly absorbed.
No additional pre-clinical data of relevance to the prescriber.
Store below 25°C in a dry place
Heat sealed cavities composed of Polyvinyl Chloride (PVC) coated with Polyvinylidene Chloride (PVDC) and laminated with polyethylene (PE), each containing 1x 4g suppository in strips of 6. The strips and a patient leaflet are packed into cardboard cartons. Pack size available: 12 x 4g.
Wash hands before opening individual packaging. The suppository is shaped for rectal insertion, ensure the tip of the suppository is inserted first. The tip should be moistened with a little cold water to aid insertion.
Martindale Pharmaceuticals Ltd