Active ingredient
- morphine sulfate
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 01883/6138.
Morphine Sulfate 10mg/ml, 15mg/ml, 20mg/ml & 30mg/ml Solution for Injection
PACKAGE LEAFLET: INFORMATION FOR THE USER
Morphine Sulfate 10mg/ml, 15mg/ml, 20mg/ml & 30mg/ml Solution for Injection
Morphine Sulfate
Read all of this leaflet carefully before you start using this medicine because it contains important information for you.
This medicine will be referred to as Morphine Sulfate Solution for Injection in the rest of this leaflet.
What is in this leaflet
1. What Morphine Sulfate Solution for Injection is and what it is used for
2. Before you are given Morphine Sulfate Solution for Injection
3. How Morphine Sulfate Solution for Injection will be given
4. Possible side effects
5. How to store Morphine Sulfate Solution for Injection
6. Contents of the pack and other information
1. What Morphine Sulfate Solution for Injection is and what it is used for
Morphine is an alkaloid with powerful pain relieving properties.
This medicine is used for the relief of severe pain.
It is also used to treat breathlessness caused by fluid in the lungs and as a pre-medication before operations.
2. Before you are given Morphine Sulfate Solution for Injection
You should not be given Morphine Sulfate Solution for Injection if:
Warnings and precautions
Talk to your doctor or pharmacist before being given Morphine Sulfate Solution for Injection if you:
Talk to your doctor or pharmacist if you experience any of the following symptoms while being given Morphine Sulfate Solution for Injection :
Other medicines and Morphine Sulfate Solution for Injection
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines including medicines obtained without prescription.
Please tell your doctor if you are taking any of the following medicines:
However if your doctor does prescribe Morphine Sulfate Solution for Injection together with sedative medicines the dose and duration of concomitant treatment should be limited by your doctor.
Please tell your doctor about all sedative medicines you are taking, and follow your doctor’s dose recommendation closely. It could be helpful to inform friends or relatives to be aware of the signs and symptoms stated above. Contact your doctor when experiencing such symptoms.
Pregnancy, breast-feeding and fertility:
This medicine should not be used if you are pregnant, trying for a baby or breast-feeding. Morphine is known to cross the placenta.
If Morphine Sulfate injection is used for a long time during pregnancy, there is a risk of the new-born child having drug withdrawal (abstinence) symptoms which should be treated by a doctor.
Driving and using machines:
This medicine may cause drowsiness. If you are affected do not drive or use machines.
This medicine can affect your ability to drive and operate machinery as it may make you sleepy or dizzy.
Talk to your doctor or pharmacist if you are not sure whether it is safe for you to drive while taking this medicine.
Having Morphine Sulfate Solution for Injection with alcohol
You are advised not to drink alcohol during your treatment with this medicine.
Morphine Sulfate Solution for Injection contains sodium and sodium metabisulfite (E223)
10 mg
This medicinal product contains 3.26 mg sodium per dose, equivalent to 0.16 % of the WHO recommended maximum daily intake of 2g sodium for an adult.
15 mg
This medicinal product contains 3.02 mg sodium per dose, equivalent to 0.15% of the WHO recommended maximum daily intake of 2g sodium for an adult.
20 mg
This medicine contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially ‘sodium-free’
30 mg
This medicine contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially ‘sodium-free’
The sodium metabisulfite may rarely cause severe hypersensitivity reactions and bronchospasm
3. How Morphine Sulfate Solution for Injection will be given
This medicine is an injection and will be given to you by your doctor. Your doctor will determine the dose you need.
The usual adult dose for relief of pain by subcutaneous injection (an injection underneath the skin) or intramuscular injection (an injection into a muscle) is 10mg every four hours, if necessary.
However, this can vary between 5mg and 20mg depending on your size and response to the drug.
For severe pain your doctor may give you a slow intravenous injection (an injection given slowly into a vein). The usual dose is quarter to half of the intramuscular dose.
If you are given too much of Morphine Sulfate Solution for Injection:
This medicine will be given to you by your doctor so it is unlikely you will receive too much. Your doctor has information on how to recognise and treat an overdose.
People who have taken an overdose may get pneumonia from inhaling vomit or foreign matter, symptoms may include breathlessness, cough and fever.
People who have taken an overdose may also have breathing difficulties leading to unconsciousness or even death.
If you experience any of the following, tell your doctor immediately:
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
If you stop using Morphine Sulfate Solution for Injection
Do not stop treatment with Morphine Sulfate Solution for Injection unless agreed with your doctor. If you want to stop the treatment with Morphine Sulfate Solution for Injection, ask your doctor how to slowly decrease the doses so you avoid abstinence symptoms. Abstinence symptoms may include body aches, tremors, diarrhoea, stomach pain, nausea, flu-like symptoms, fast heartbeat and large pupils. Psychological symptoms include an intense feeling of unsatisfaction, anxiety and irritability
4. Possible Side Effects
Like all medicines Morphine Sulfate Solution for Injection can cause side effects, although not everybody gets them.
Tell your doctor or nurse immediately if you experience any of the following serious side effects:
Other side effects include:
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to Store Morphine Sulfate Solution for Injection
Keep out of the sight and reach of children.
You should not be given Morphine Sulfate Solution for Injection after the expiry date on the ampoule and carton label. The expiry date refers to the last day of that month. The doctor or nurse will check that the product has not passed this date.
Do not store above 25°C.
Keep the ampoule in the outer carton in order to protect from light.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. Contents of the pack and other information
What Morphine Sulfate Solution for Injection contains:
The active ingredient: morphine sulfate.
Each ampoule contains 10, 15, 20 or 30 mg morphine sulfate.
The other ingredients: sodium chloride, sodium metabisulfite (E223) and water for injections. This medicine may also contain sodium hydroxide solution or sulfuric acid solution.
What Morphine Sulfate Solution for Injection looks like and contents of the pack:
Morphine Sulfate Solution for Injection is a clear, colourless or almost colourless, particle free solution, supplied in clear, colourless 1ml glass ampoules. This medicine is supplied to your doctor in packs of 10 ampoules.
Manufacturer:
Marketing Authorisation Holder:
Product Licence Numbers:
PL 01883/6138. PL 01883/6176. PL 01883/6177. PL 01883/6178
This leaflet was last revised in August 2020
D05384
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