This information is intended for use by health professionals
Chloramphenicol Ear Drops BP 5% w/v
Chloramphenicol BP 5% w/v
For the treatment of bacterial infection of the external ear.
Adults, Children and the Elderly
Apply 3 - 4 drops into the affected ear 2 - 3 times daily for up to 1 week.
Following administration of ear drops patients should be advised to lie down with the affected ear uppermost for a minimum of 10 minutes. After this time cotton wool may be inserted into the ear and normal activities resumed.
Only use if considered essential by the physician.
Hypersensitivity to the drug or Propylene Glycol or if the ear drum is perforated.
Avoid use for more than 1 week as this may result in sensitivity to chloramphenicol or the emergence of resistant organisms.
Chloramphenicol crosses the placenta but no problems have been reported with the use of ear drops. As with all drugs in pregnancy and during breast feeding, care should be taken in assessing the risk-benefits.
May occasionally cause bone marrow hypoplasia, blood dyscrasia or hypersensitivity reactions.
Overdose is unlikely to occur with this preparation.
Chloramphenicol is a broad spectrum antibiotic which acts by interfering with bacterial protein synthesis.
When used topically systemic absorption is very low.
There is no pre-clinical safety data of relevance to the prescriber, therefore, none is presented in this section.
None specific to this preparation.
Store at 2-8°C in a dry dark place. Do not freeze.
A 10ml low density polyethylene bottle with dropper insert and high density polyethylene tamper evident cap.
Martindale Pharmaceuticals Ltd
| Date of first authorisation:
|| 6th June 1997
| Renewal Date:
|| 2nd February 1998