What is a Patient Information Leaflet and why is it useful?

The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.

Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.

The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL08553/0458.


Attia 200 mg Modified-Release Capsules, Hard

PACKAGE LEAFLET: INFORMATION FOR THE USER

Attia 200 mg Modified-Release Capsules, Hard

Dipyridamole

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

What is in this leaflet:

1. What Attia is and what it is used for
2. What you need to know before you take Attia
3. How to take Attia
4. Possible side effects
5. How to store Attia
6. Contents of the pack and other information

1. What Attia is and what it is used for

Dipyridamole belongs to a group of medicines called anti-thrombotic agents, which are used to prevent the formation of blood clots. Each capsule contains 200 mg of dipyridamole, which is slowly released in your body over a number of hours.

Attia is used to

  • help prevent blood clots which sometimes occur with the use of artificial heart valves
  • reduce the risk of having another stroke (a blood clot in the brain) in people who have already suffered a stroke.

2. What you need to know before you take Attia

Do not take Attia if you:

  • are allergic to dipyridamole or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions:

Talk to your doctor or pharmacist before taking your medicine if:

  • you are pregnant, likely to become pregnant, or if you are breast-feeding
  • you have angina or other heart problems (including heart valve or circulation problems), or have had a recent heart attack
  • you have myasthenia gravis (a condition characterised by extreme tiredness and muscle weakness)
  • you have a bleeding disorder.

In people who have gallstones, the dipyridamole in this medicine can be absorbed into the gallstones.

If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Attia.

If you are having heart tests

Dipyridamole can also be given by injection into a vein to test if the heart is functioning properly (myocardial imaging). This means that the test and your medicine may contain the same substance.

If you are going to have this test, you should stop taking the capsules 24 hours before you have this test.

Other medicines and Attia

Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. This includes herbal medicines. This is because Attia can affect the way some other medicines work. Also some other medicines can affect the way Attia works.

In particular, tell your doctor or pharmacist if you are taking any of the following medicines:

  • adenosine (for heart problems or tests on the heart)
  • blood thinning medicines (such as warfarin). If so, tell them at your next visit to the anticoagulant clinic that you are now taking Attia.
  • medicines for high or low blood pressure
  • medicines for muscle weakness such as something called a ‘cholinesterase inhibitor’
  • aspirin (or planning to take aspirin for any condition).

Attia with alcohol

Do not take Attia at the same time as an alcoholic drink.

Pregnancy and breast-feeding

Tell your doctor if you are

  • pregnant or likely to get pregnant
  • breast-feeding

Your doctor will advise you whether to take Attia.

Driving and using machines

You may feel dizzy while taking Attia. If this happens do not drive or use any tools or machines.

Attia contains ponceau 4R (E124)

Attia capsules contain the colouring agent ponceau 4R (E124), which may cause allergic reactions.

3. How to take Attia

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Swallow the capsule whole without chewing/ crushing it.

Adults: One capsule in the morning and one in the evening with meals.

Children: Do not give to children.

If you take more Attia than you should

Do not take more than your doctor has prescribed. It may cause symptoms such as feeling warm, sweating, racing of pulse, restlessness, weakness, dizziness and chest pain. If you take more than the recommended daily dose, consult a doctor or go to a hospital straight away. Take the medicine pack with you, even if there are no capsules left.

If you forget to take Attia

If you forget to take a dose, take it as soon as you remember but if it is nearly time for your next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Attia can cause side effects, although not everybody gets them.

Contact your doctor at once if you develop any of the following rare allergic reactions:

  • breathing difficulties
  • large welts or swelling of the skin near the eyes, lips, hands, feet or inside of the throat (which may cause difficulty breathing), runny nose and severe rash with itching.

Other side effects that have been reported are described below. They are listed as either very common, common or not known.

Very common (may affect more than 1 in 10 people)

  • headache
  • feeling dizzy
  • feeling sick (nausea)
  • diarrhoea

Common (may affect up to 1 in 10 people)

  • muscle pain
  • being sick (vomiting)
  • worsening of symptoms of heart disease such as chest pain (angina) and heart beat problems (arrhythmias), fatigue, breathlessness

Not known (frequency cannot be estimated from the available data)

  • hot flushes
  • lowering of blood pressure or increased heart rate
  • a blood problem called ‘thrombocytopenia’ which can cause bruising and prolonged bleeding from wounds including during or after surgery.

Reporting of side effects

If you get any side effects, talk to your doctor, hospital pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine.

5. How to store Attia

Keep out of the sight and reach of children.

This medicinal product does not require any special temperature storage conditions. Keep the bottle tightly closed. Store in the original package, in order to protect from moisture.

Do not open the container until you are ready to begin taking this course of treatment.

Discard any remaining capsules 30 days after first opening the bottle.

Do not use Attia after the expiry date which is stated on the bottle/label after ‘Exp’. The expiry date refers to the last day of that month.

Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.

6. Content of the pack and other information

What Attia contains

The active substance (which makes the medicine work) is 200 mg dipyridamole.

The other ingredients are: hypromellose, tartaric acid, acacia, povidone, methacrylic acid-methyl methacrylate copolymer (1:2), hypromellose phthalate, dimethicone, triacetin, talc and stearic acid.

The HPMC capsule shell contains: Hypromellose, brilliant blue (E133), ponceau 4R (E124), quinoline yellow (E104), titanium dioxide (E171), Carrageenan and Potassium Acetate. The white imprinting ink contains: shellac, potassium hydroxide and titanium dioxide (E171).

What Attia looks like and contents of the pack

Attia is a modified-release capsule filled with yellow to orange coloured pellets filled in size “0xel” hard capsules with opaque dark red cap and opaque dark orange body, imprinted ‘DPM’ on cap and ‘200’ on body with white ink.

Attia capsules are supplied in HDPE bottles, with desiccant.

Pack size: 60 capsules per bottle.

Marketing authorisation holder and manufacturer

Dr. Reddy’s Laboratories (UK) Ltd.
6 Riverview Road
Beverley
HU17 0LD

This leaflet was last updated in 09/2018