Active ingredient
- adrenaline acid tartrate
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 12064/0006 .
Adrenaline (Epinephrine) Injection 1:10,000 (pre-filled syringe)
PACKAGE LEAFLET: INFORMATION FOR THE USER
Adrenaline (Epinephrine) Injection 1:10,000
(Referred to as ‘Adrenaline injection’ in this leaflet)
Adrenaline acid tartrate
Read all of this leaflet carefully before you start using this medicine because it contains important information for you
What is in this leaflet:
1. What Adrenaline injection is, and what it is used for
2. What you need to know before Adrenaline injection is given
3. How Adrenaline injection is given
4. Possible side effects
5. How to store Adrenaline injection
6. Contents of the pack and other information
1. What Adrenaline injection is, and what it is used for
Adrenaline injection belongs to a group of medicines called adrenergic and dopaminergic agents.
This medicine is used for:
2. What you need to know before you are given Adrenaline Injection
You must not be given Adrenaline Injection:
If you are allergic (hypersensitive) to any ingredients of this medicine (listed in section 6) where an alternative presentation of Adrenaline or alternative vasopressor is available.
Warnings and precautions
Adrenaline injection is indicated for emergency treatment. Continuous medical supervision is necessary after administration.
Precautions for use
The risk of side effects is increased if you:
Other medicines and Adrenaline injection
Tell your doctor if you are taking, have recently taken or might take any other medicines.
Medicines that may interact with Adrenaline injection include:
Pregnancy & breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor, pharmacist or nurse for advice before you are given this medicine.
Driving and using machines
Having Adrenaline injection does not affect your ability to drive or use machines.
Adrenaline injection contains sodium This medicinal product contains 2.70 mg of sodium per ml of solution for injection. This needs to be taken into consideration by patients on strict sodium diet.
The product also contains Sodium Metabisulphite which may cause allergic (hypersensitive) type reactions in some people and can lead to breathing difficulties or collapse. People with a history of asthma or allergies are most likely to experience these problems.
3. How Adrenaline injection is given
Your doctor, nurse or paramedic will give Adrenaline injection to you either into a vein (intravenous) or into a bone (intraosseous). Your doctor will decide the correct amount for you, and when and how this should be given.
Adrenaline must not be injected into the fingers, toes, ears, nose or genital area.
This medicinal product is not intended to deliver volumes of less than 2ml.
In case of life threatening allergic reactions (acute anaphylaxis):
Adults will be given a dose of 0.05 mg (0.5 ml of Adrenaline 1:10,000 solution) repeated as necessary until the desired response is achieved.
In case of cardiac arrest:
Adults: 1 mg (10 ml of Adrenaline 1:10,000 solution) is given into a vein or into a bone every 3-5 minutes until the heart starts to work.
Children above 5 kg: 10 micrograms/kg (0.1 ml/kg of Adrenaline 1:10,000 solution) is given into a vein or into a bone every 3-5 minutes until the heart starts to work.
This medicinal product is not suitable for delivering a dose of less than 0,5 ml and should therefore, not be used in neonates and infants for which the body weight is less than 5 kg.
4. Possible side effects
Like all medicines, Adrenaline injection can cause side effects, although not everybody gets them.
In high dosages or for patients sensitive to adrenaline, side effects are:
Repeated local injections may produce necrosis (tissue damage) at the site of injection as a result of vascular constriction (blood vessel constriction).
In all cases, after administration of Adrenaline injection medical supervision is necessary.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via Yellow Card Scheme - Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Adrenaline injection
Keep out of the sight and reach of children.
Your doctor, nurse or paramedic will check that the expiry date on the label has not passed before giving Adrenaline injection to you. The expiry date refers to the last day of that month.
Adrenaline (Epinephrine) is sensitive to light, therefore Adrenaline injections must always be kept in the original outer carton.
Do not store above 25°C and do not freeze.
You should not be given Adrenaline injection if it has been used or shows signs of visible damage.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. Content of the pack and other information
What Adrenaline (Epinephrine) Injection 1:10,000 contains
The active ingredient is Adrenaline (Epinephrine) as acid tartrate.
Each 10ml solution for injection contains 1mg of adrenaline(epinephrine) as the acid tartrate.
The other ingredients are Sodium Chloride, Citric Acid Monohydrate, Sodium Citrate Dihydrate, Sodium Metabisulphite and Water for Injections. Dilute Hydrochloric acid may be added to adjust the acidity.
What Adrenaline injection looks like and contents of the pack
Adrenaline injection is a clear colourless solution supplied in a pre-filled syringe. Each prefilled syringe contains 10ml of the solution.
Marketing Authorisation Holder:
Manufacturers:
This leaflet was last revised in 03/2018
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