The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL35533/0105.
Eysano 2.5mg/ml and 5mg/ml Eye Drops, Solution
2.5mg/ml eye drops, solution
5mg/ml eye drops, solution
Eysano eye drops are contained within a novel multidose eye drop bottle, which allows for the solution not to contain any preservatives. Due to the design of the container, administration with these eye drops is not the same as standard eye drop bottles.
Please read the full instructions on the correct use of this product in Section 3 of the leaflet ("How to use Eysano"), before using these eye drops.
1. What Eysano is and what it is used for
2. What you need to know before you use Eysano
3. How to use Eysano
4. Possible side effects
5. How to store Eysano
6. Contents of the pack and other information
Eysano contains a substance called timolol which belongs to a group of medicines called beta-blockers. Timolol lowers the pressure in your eye(s). It is used to treat chronic open-angle and secondary glaucoma, when the pressure in the eye is raised, in adults.
Eysano eye drops, solution is a sterile solution that does not contain a preservative.
If you are not sure whether you should use Eysano talk to your doctor or pharmacist.
Talk to your doctor before using Eysano if you have now or have had in the past:
If you have a history of contact hypersensitivity to silver, you should not use this product.
Tell your doctor before you have an operation that you are using Eysano as timolol may change the effects of some medicines used during anaesthesia.
If you suspect that Eysano is causing an allergic reaction or hypersensitivity (for example, skin rash or redness and itching of the eye) contact your doctor immediately.
Eysano should generally be used with caution in young patients. In newborns, infants and toddlers Eysano should be used with extreme caution. If coughing, wheezing, abnormal breathing or abnormal pauses in breathing (apnoea) occur, the use of the medicine should be stopped immediately. Contact your doctor as soon as possible. A portable apnoea monitor may also be helpful.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Eysano can affect or be affected by other medicines you are using, including other eye drops for the treatment of glaucoma.
Tell your doctor if you are using or intend to use medicines to lower blood pressure, heart medicine or medicines to treat diabetes.
It is important to tell your doctor before using Eysano if you are taking one or more of the following medicines:
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
Use in pregnancy
Do not use Eysano if you are pregnant unless your doctor considers it necessary.
Use in breast-feeding
Do not use Eysano if you are breast-feeding. Timolol may get into your milk.
There are possible side effects associated with Eysano, such as dizziness, tiredness and changes in your eyesight, such as blurred vision, drooping of the upper eyelid (making the eye stay half closed), double vision which may affect your ability to drive and/or operate machinery.
Do not drive and/or operate machinery until you feel well and your vision is clear.
Each ml of Eysano 2.5mg/ml solution contains 12.72mg phosphates.
Each ml of Eysano 5mg/ml solution contains 11.78mg phosphates.
If you suffer from severe damage to the clear layer at the front of the eye (the cornea), phosphates may cause in very rare cases cloudy patches on the cornea due to calcium build-up during treatment.
Always use this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. The doctor will decide how many drops you should take each day and how long you should use them.
The recommended dose is one drop in the affected eye(s) once or twice (one in the morning and one in the evening) each day.
Do not change your recommended dose without talking to your doctor.
Do not allow the tip of the bottle to touch the eye or areas around the eye. It could cause injury to your eye. The eye drops solution may become contaminated with bacteria that can cause eye infections leading to serious damage of the eye, even loss of vision.
To avoid possible contamination of the bottle, keep the tip of the bottle away from contact with any surface.
Before instillation of the eye drops:
1. Hold the bottle directly below the cap and turn the cap to open the bottle. Do not touch anything with the tip of the bottle to avoid contamination of the solution.
2. Tilt your head backwards and hold the bottle above your eye.
3. Pull the lower eyelid down and look up. Squeeze the bottle gently in the middle and let a drop fall into your eye. Please note that there might be a few seconds delay between squeezing and the drop coming out. Do not squeeze too hard. If you are not sure how to administer your medicine, ask your doctor, pharmacist or nurse.
4. Blink a few times so that the drop spreads over the eye.
5. After using Eysano, press a finger into the corner of your eye, by the nose for 2 minutes. This helps to stop the eye drops getting into the rest of your body.
6. Follow the instructions 2-5 for dropping also into the other eye.
7. After use and prior to recapping, the bottle should be shaken once in a downwards direction, without touching the dropper tip, in order to remove any residual liquid on the tip. This is necessary in order to ensure delivery of subsequent drops.
There might remain a small amount of solution in the bottle at the end. This is accounted for by an overfill of all bottles ensuring that 5ml solution can always be dispensed.
Do not use the eye drops for longer than 28 days after first opening the bottle.
Before your child starts to use Eysano, your child’s doctor will have carried out a detailed medical examination and decided whether or not this medicine is suitable. Your child, especially a newborn, should be closely monitored for one to two hours after the first dose and carefully monitored for any signs of side effects.
Method of administration for use in children and adolescents
One drop only of Eysano should be instilled into the affected eye(s) each time. Follow the “Instructions for use” above when administering the eye drops.
Duration of treatment for use in children and adolescents
Your child’s doctor will decide for how long the eye drops will be needed.
If you put too many drops in your eye or swallow any of the drops, you may:
If this happens, contact your doctor immediately.
It is important to take Eysano as prescribed by your doctor.
If you want to stop using this medicine talk to your doctor first. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Like all medicines, this medicine can cause side effects, although not everybody gets them.
You can usually carry on taking the drops, unless the effects are serious. If you are worried, talk to a doctor or pharmacist. Do not stop using Eysano without speaking to your doctor.
See your doctor immediately if you notice any of the following side effects for which you may need urgent medical treatment:
Rare (may affect up to 1 in 1,000 people)
Common (may affect up to 1 in 10 people)
Uncommon (may affect up to 1 in 100 people)
Rare (may affect up to 1 in 1,000 people)
Not known (frequency cannot be estimated from the available data)
Like other medicines applied into eyes, timolol is absorbed into the blood. This may cause similar side effects as seen with intravenous and/or oral beta-blocking agents. Incidence of side effects after topical ophthalmic administration is lower than when medicines are, for example, taken by mouth or injected. The following additional side effects were seen within the class of beta-blockers when used for treating eye conditions:
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme (website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store).
By reporting side effects you can help provide more information on the safety of this medicine.
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and the bottle after EXP. The expiry date refers to the last day of that month.
This medicine does not require any special storage conditions.
Do not use the eye drops for longer than 28 days after first opening the bottle. Write down the date you opened the bottle in the space on the bottle label and box.
Make sure the bottle is properly closed.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
The active substance is timolol.
Eysano is available in two strengths:
Eysano 2.5mg/ml eye drops, solution is presented as a clear, colourless aqueous solution in a white opaque 11ml LDPE bottle and white Novelia nozzle (HDPE and silicone) with a white HDPE cap.
Eysano 5mg/ml eye drops, solution is presented as a clear, colourless aqueous solution in a white opaque 11ml LDPE bottle and white Novelia nozzle (HDPE and silicone) with a white HDPE cap.
Pack sizes: 1 or 2 bottles of 5ml solution in a cardboard box.
Not all pack sizes may be marketed.
Marketing Authorisation Holder
This leaflet was last revised in: 11/2019