- vancomycin hydrochloride
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 13621/0030.
Vancocin Matrigel 125mg Hard Capsules
PACKAGE LEAFLET: INFORMATION FOR THE USER
Vancocin Matrigel 125mg Hard Capsules
Vancomycin (as hydrochloride)
The name of your medicine is Vancocin Matrigel 125mg Hard Capsules, which will be referred to as Vancocin capsules throughout this document.
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
In this leaflet:
1. What Vancocin capsules are and what they are used for
2. What you need to know before you take Vancocin capsules
3. How to take Vancocin capsules
4. Possible side effects
5. How to store Vancocin capsules
6. Contents of the pack and other information
1 What Vancocin capsules are and what they are used for
Vancocin capsules contain the active ingredient vancomycin. Vancomycin is an antibiotic that belongs to a group of antibiotics called ‘glycopeptides’. Vancomycin works by eliminating certain bacteria that cause infections.
Vancomycin is used in adults and adolescents from 12 years of age for the treatment of infections of the mucosa of the small and the large intestines with damage to the mucosae (pseudomembranous colitis), caused by the Clostridium difficile bacterium.
2 What you need to know before you take Vancocin capsules
Do not take Vancocin capsules:
Warnings and precautions
Talk to your doctor or pharmacist before taking Vancocin capsules
Vancomycin capsules are not appropriate for children under 12 years or for adolescents unable to swallow them. Other forms of this medicine may be more suitable for children; ask your doctor or pharmacist.
Other medicines and Vancocin capsules
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. This is especially important of the following, as they may interact with your Vancocin capsules:
It may still be alright for you to be given Vancocin capsules and your doctor will be able to decide what is suitable for you.
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Driving and using machines
Vancocin capsules should not affect your ability to drive or use machines.
3 How to take Vancocin capsules
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
Adults and adolescents (from 12 years and older)
The recommended dose is 125mg every 6 hours.
In some cases, your doctor may decide to give a higher daily dose of up to 500mg every 6 hours.
The maximum daily dose should not exceed 2g.
If you suffered other episodes (infection of the mucosa) before you may need different dose and different duration of the therapy.
Method of administration
For oral use.
Swallow the capsules whole with water.
The usual duration of the therapy is 10 days but it may be different depending on the individual response to treatment for every patient.
4 Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Vancomycin can cause allergic reactions, although serious allergic reactions (anaphylactic shock) are rare. Tell your doctor immediately if you get any sudden wheeziness, difficulty in breathing, redness on the upper part of the body, rash or itching.
Stop using vancomycin and seek medical attention immediately if you notice any of the following symptoms:
Uptake of vancomycin from the gastrointestinal tract is negligible. Therefore, adverse events following intake of capsules are unlikely.
However, if you have an inflammatory disorder of the digestive tract, especially if you also have a kidney disorder, similar side effects as those that occur when vancomycin is given by infusion may appear. Therefore, the side effects and frequencies which are reported for vancomycin given as infusion are included.
Common side effects (may affect up to 1 in 10 people):
Uncommon side effects (may affect up to 1 in 100 people):
Rare side effects (may affect up to 1 in 1,000 people):
Very rare side effects (may affect up to 1 in 10,000 people):
Not known (frequency cannot be estimated from the available data):
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly (see details below). By reporting side effects you can help provide more information on the safety of this medicine.
or search for MHRA Yellow Card in the Google Play or Apple App Store
5 How to store Vancocin capsules
Keep this medicine out of the sight and reach of children.
Do not store above 25°C. Store in the original blister in order to protect from moisture.
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.
6 Contents of the pack and other information
What Vancocin capsules contain
The active substance is vancomycin hydrochloride 125mg.
The other ingredients are:
Macrogol 6000, gelatin, indigo carmine, red iron oxide, yellow iron oxide and titanium dioxide.
The printing ink contains:
Shellac, propylene glycol, iron oxide red (E172) and potassium hydroxide.
What Vancocin capsules look like and contents of the pack
Vancocin capsules are contained in blister packs of 20 capsules (2 strips of 10 capsules) or 28 capsules (4 strips of 7 capsules).
The capsules are dark blue and brown coloured and printed with the number 3125.
Not all pack sizes may be marketed.
Marketing Authorisation Holder
This leaflet was last revised in
Other sources of information
Antibiotics are used to cure bacterial infections. They are ineffective against viral infections.
If your doctor has prescribed antibiotics, you need them precisely for your current illness,
Despite antibiotics, some bacteria may survive or grow. This phenomenon is called resistance: some antibiotic treatments become ineffective.
Misuse of antibiotics increases resistance. You may even help bacteria become resistant and therefore delay your cure or decrease antibiotic efficacy if you do not respect appropriate:
Consequently, to preserve the efficacy of this drug:
1. Use antibiotics only when prescribed
2. Strictly follow the prescription
3. Do not re-use any antibiotic without medical prescription, even if you want to treat a similar illness.
4. Never give your antibiotic to another person; maybe it is not adapted to her/his illness
5. After completion of treatment, return all unused drugs to your chemist’s shop to ensure they will be disposed of correctly.
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