Active ingredient
- metoclopramide hydrochloride
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 00427/0117.
Metoclopramide Hydrochloride 5mg/5ml Oral Solution
Package leaflet: Information for the user
Metoclopramide Hydrochloride 5mg/5ml Oral Solution
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
What is in this leaflet
1. What Metoclopramide Hydrochloride 5mg/5ml Oral Solution is and what it is used for
2. What you need to know before you take Metoclopramide Hydrochloride 5mg/5ml Oral Solution
3. How to take Metoclopramide Hydrochloride 5mg/5ml Oral Solution
4. Possible side effects
5. How to store Metoclopramide Hydrochloride 5mg/5ml Oral Solution
6. Contents of the pack and other information
1. What Metoclopramide Hydrochloride 5mg/5ml Oral Solution is and what it is used for
The name of your medicine is Metoclopramide Hydrochloride 5mg/5ml Oral Solution (known as Metoclopramide in this leaflet). This belongs to a group of medicines called antiemetics.
Metoclopramide works on a part of the brain that prevents you from feeling sick (nausea) and being sick (vomiting).
Adult population
Metoclopramide is used in adults:
Paediatric population
Metoclopramide is indicated in children (aged 1-18 years) if other treatment does not work or cannot be used to prevent delayed nausea and vomiting that may occur after chemotherapy.
2. What you need to know before you take Metoclopramide Hydrochloride 5mg/5ml Oral Solution
Do not take Metoclopramide if:
Do not give Metoclopramide to a child less than 1 year of age (see below “Children and adolescents”).
Do not take Metoclopramide if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Metoclopramide.
Warnings and precautions
Talk to your doctor or pharmacist before taking Metoclopramide if:
If vomiting persists, even when you are taking this medicine, you should talk to your doctor.
Tests whilst taking Metoclopramide
You must wait at least 6 hours between each metoclopramide dose, even in case of vomiting and rejection of the dose, in order to avoid overdose.
Do not exceed 3 months treatment because of the risk of involuntary muscle spasms.
Children and adolescents
Uncontrollable movements (extrapyramidal disorders) may occur in children and young adults. This medicine must not be used in children below 1 year of age because of the increased risk of the uncontrollable movements (see above “Do not take Metoclopramide if”).
If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking metoclopramide.
Other medicines and Metoclopramide
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines bought without a prescription, including herbal medicines. This is because metoclopramide can affect the way some other medicines work. Also, some medicines can affect the way metoclopramide works.
In particular tell your doctor if you are taking any of the following:
Taking Metoclopramide with alcohol
Do not drink alcohol whilst taking metoclopramide. This is because alcohol will make you drowsy and taking metoclopramide with it may make you even more drowsy. Also, it may make your blood alcohol levels higher than normal.
Pregnancy, breast-feeding and fertility
If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before being given this medicine. If necessary, Metoclopramide may be taken during pregnancy. Your doctor will decide whether or not you should be given this medicine.
Metoclopramide is not recommended if you are breast-feeding because metoclopramide passes into breast milk and may affect your baby.
Driving and using machines
Metoclopramide may make you drowsy, feel dizzy and can cause movement disorders or have uncontrollable twitching, jerking or writhing movements and unusual muscle tone causing distortion of the body after taking Metoclopramide. This may affect your vision and also interfere with your ability to drive and use machines.
Metoclopramide Oral Solution contains methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), sorbitol (E420) and propylene glycol (E1520):
3. How to take Metoclopramide Hydrochloride 5mg/5ml Oral Solution
All indications (adult patients)
The recommended single dose is 10 mg (10 ml), repeated up to three times daily.
The maximum recommended dose per day is 30 mg (30 ml) or 0.5 mg/kg body weight.
The maximum recommended treatment duration is 5 days.
To prevent delayed nausea and vomiting that may occur after chemotherapy (children aged 1-18 years)
The recommended dose is 0.1 to 0.15 mg/kg body weight, repeated up to 3 times daily, taken by mouth (oral route).
The maximum dose in 24 hours is 0.5 mg/kg body weight.
Dosing table
Age: 1-3 years, Body Weight: 10-14 kg, Dose: 1 mg (1 ml), Frequency: Up to 3 times daily
Age: 3-5 years, Body Weight: 15-19 kg, Dose: 2 mg (2 ml), Frequency: Up to 3 times daily
Age: 5-9 years, Body Weight: 20-29 kg, Dose: 2.5 mg (2.5 ml), Frequency: Up to 3 times daily
Age: 9-18 years, Body Weight: 30-60 kg, Dose: 5 mg (5 ml), Frequency: Up to 3 times daily
Age: 15-18 years, Body Weight: over 60 kg, Dose: 10 mg (10 ml), Frequency: Up to 3 times daily
You should not take this medicine for more than 5 days to prevent delayed nausea and vomiting that may occur after chemotherapy.
Taking this medicine
Measuring your dose using the oral syringe provided
Instructions for use of the oral syringe.
Taking this medicine via NG or PEG tubes
1. Ensure the tube is clear before taking the medicine.
2. Flush the tube with 5mL of water.
3. Administer the medicine into the tube with a suitable measuring device, which will be provided by your doctor, pharmacist or nurse. Do not use the oral syringe provided in the pack.
4. Flush the tube again with 5mL of water.
Older people
The dose may need to be reduced depending on kidney problems, liver problems and overall health.
Adults with kidney problems
Talk to your doctor if you have kidney problems. The dose should be reduced if you have moderate or severe kidney problems.
Adults with liver problems
Talk to your doctor if you have liver problems. The dose should be reduced if you have severe liver problems.
Children and adolescents
Metoclopramide must not be used in children aged less than 1 year (see section 2).
If you take more Metoclopramide Oral Solution than you should
If you forget to take Metoclopramide Oral Solution
If you stop taking Metoclopramide Oral Solution
Do not stop taking the medicine unless your doctor tells you to. The symptoms may come back if treatment is stopped too early.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, Metoclopramide Oral Solution can cause side effects although not everybody gets them.
Stop taking Metoclopramide Oral Solution and see a doctor straight away if you have:
Other side effects reported with metoclopramide:
Very common (may affect more than 1 in 10 people)
Common (may affect up to 1 in 10 people)
Uncommon (may affect up to 1 in 100 people)
Rare (may affect up to 1 in 1,000 people)
Not known (frequency cannot be estimated from the available data)
If you get any side effects, talk to your doctor or pharmacist. This includes any side effects not listed in this leaflet.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Metoclopramide Hydrochloride 5mg/5ml Oral Solution
6. Contents of the pack and other information
What Metoclopramide Oral Solution contains
What Metoclopramide Oral Solution looks like and contents of the pack
A colourless solution with a lime and lemon odour.
It comes in a brown glass bottle holding 150ml of solution.
A 10ml oral syringe with markings at every 1ml and intermediate marks at every 0.5ml is provided to help measure your dose.
Marketing Authorisation Holder and Manufacturer
This leaflet was last revised in 05/2020
F7AD1ADJ1
Rosemont House, Yorkdale Industrial Park, Braithwaite Street, Leeds, Yorkshire, LS11 9XE
+44 (0)113 244 1400
+44 (0)800 919 312
+44 (0)113 245 3567
+44 (0)795 762 3515