The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 29831/0113.
Hyalase 1500 I.U. Powder for Solution for Injection/Infusion or Hyaluronidase 1500 I.U. Powder for Solution for Injection/Infusion
HYALASE® 1500 I.U. Powder for Solution for Injection/Infusion
1. What Hyalase® is and what it is used for
2. Before you are given Hyalase®
3. How Hyalase® should be given
4. Possible side-effects
5. How to store Hyalase®
6. Further information
The name of your medicine is Hyalase®. The active ingredient in Hyalase® is hyaluronidase.
Hyalase® is an enzyme, a natural substance that activates processes in the body. It is used to temporarily break down the natural barriers in the body tissues so that injections or fluids injected under the skin or into muscle are more easily spread and absorbed.
Hyalase® is also used to enable excess fluids and blood in the tissues to be more easily reabsorbed.
Hyalase® should not be administered by Intravenous Injection.
Hyalase® should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs. If you are taking dopamine or clonidine, or any other alpha agonist drug, please tell your doctor or nurse before you are given this medicine.
If you have any doubts about whether this medicine should be administered then talk to your doctor or nurse before it is given to you.
You should let your doctor know if you are pregnant, wish to become pregnant, or are breast-feeding before Hyalase® is administered.
Hyalase® has not been reported to affect ability to drive or operate machines.
Your doctor will decide the dose and route of administration that is best for you. If you do not understand what you are being given, or are in any doubt, ask your doctor or nurse.
Your doctor will decide which dose is best for you. If you think too much medicine has been given to you contact your doctor or nurse.
If you think that an injection has been missed, speak to you doctor or nurse.
Like all medicines, Hyalase® may cause side-effects in some patients.
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting systems listed below:
By reporting side effects you can help provide more information on the safety of this medicine.
Keep out of the sight and reach of children
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.
Hyalase® is a sterile, freeze-dried powder in 1 ml neutral glass ampoule, containing 1500 international units of the active ingredient (hyaluronidase).
The registered pack size is 10 x 1ml glass ampoules.
To listen to or request a copy of this information in Braille, large print or audio please call, free of charge:
0800 198 5000 (UK only)
Please be ready to give the following information:
Product Name Reference Number
Hyalase® for Injection/Infusion 1500iu/ml PL 29831/0113
Marketing Authorisation Holder:
Leaflet prepared: January 2022