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Rizatriptan 5mg and 10mg tablets
Rizatriptan 5mg tablets
Rizatriptan 10mg tablets
1. What this medicine is and what it is used for
2. What you need to know before you take this medicine
3. How to take this medicine
4. Possible side effects
5. How to store this medicine
6. Contents of the pack and other information
Rizatriptan belongs to a class of medicines called selective serotonin 5-HT1B/1D receptor agonists.
This medicine is used to treat the headache phase of a migraine attack in adults.
Treatment with this medicine reduces swelling of blood vessels surrounding the brain. This swelling results in the headache pain of a migraine attack.
If you are not sure if any of the above applies to you, talk to your doctor or pharmacist before taking this medicine.
Talk to your doctor or pharmacist before taking this medicine if:
If you take rizatriptan too often, you may get a chronic headache.
In such cases you should contact your doctor as you may have to stop taking this medicine.
Tell your doctor or pharmacist about your symptoms. Your doctor will decide if you have a migraine. You should take this medicine only for a migraine attack. This medicine should not be used to treat headaches that might be caused by other, more serious conditions.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. This includes herbal medicines and those you normally take for a migraine. This is because rizatriptan can affect the way some medicines work. Also, other medicines can affect this medicine.
The above listed medicines when taken with rizatriptan may increase the risk of side effects.
You should wait at least 6 hours after taking this medicine before you take ergotamine-type medicines such as ergotamine or dihydro-ergotamine or methysergide.
You should wait at least 24 hours after taking ergotamine-type medicines before taking this medicine.
Ask your doctor for instructions and the risks about taking this medicine if you are also taking:
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.
This medicine can take longer to work if it is taken after food. Although it is better to take it on an empty stomach, you can still take it if you have eaten.
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
It is not known whether rizatriptan is harmful to an unborn baby when taken by a pregnant woman.
Breast-feeding should be avoided for 24 hours after treatment.
You may feel sleepy or dizzy while taking rizatriptan. If this happens, do not drive or use any tools or machines.
Rizatriptan is used to treat migraine attacks. Take this medicine as soon as possible after your migraine headache has started. Do not use it to prevent an attack.
Always take this medicine exactly as your doctor has told you.
Check with your doctor or pharmacist if you are not sure.
The recommended dose is 10mg.
If you are currently taking propranolol or have kidney or liver problems, you should use the 5mg dose of rizatriptan. You should leave at least 2 hours between taking propranolol and rizatriptan up to a maximum of 2 doses in a 24-hour period.
Rizatriptan tablets should be taken by mouth and swallowed whole with liquid. The tablets are not intended to be divided.
In some patients, migraine symptoms can return within a 24-hour period. If your migraine does return you can take an additional dose of this medicine. You should always wait at least 2 hours between doses.
If you do not respond to the first dose of this medicine during an attack, you should not take a second dose of rizatriptan for treatment of the same attack. It is still likely, however, that you will respond to this medicine during the next attack.
Do not take more than 2 doses of rizatriptan in a 24-hour period. You should always wait at least 2 hours between doses.
If your condition worsens, seek medical attention.
The use of this medicine in children under 18 years of age is not recommended.
There have been no full studies to look at how safe and effective this medicine is amongst patients older than 65 years.
If you take more rizatriptan than you should, talk to your doctor or pharmacist straight away. Take the medicine pack with you.
Signs of overdose can include dizziness, drowsiness, vomiting, fainting and slow heart rate.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with this medicine.
During studies in adults, the most common side effects reported were dizziness, sleepiness and tiredness.
Tell your doctor right away if you have symptoms of allergic reactions, serotonin syndrome, heart attack or stroke (see the list below).
In addition, tell your doctor if you experience any symptoms that suggest an allergic reaction (such as a rash or itching) after taking this medicine.
Common: may affect up to 1 in 10 people
Uncommon: may affect up to 1 in 100 people
Rare: may affect up to 1 in 1000 people
Not known: frequency cannot be estimated from the available data
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme (website: www.mhra.gov.uk/yellowcard) or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of that month.
Do not store above 30°C.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
The active substance is rizatriptan.
Each 5mg tablet contains 7.265mg of rizatriptan benzoate equivalent to 5mg of rizatriptan.
Each 10mg tablet contains 14.53mg of rizatriptan benzoate equivalent to 10mg of rizatriptan.
The other ingredients are: microcrystalline cellulose, maize starch, pregelatinised, starch (maize), iron oxide red (E172), magnesium stearate.
5mg tablets are pale pink, round and biconvex with dimensions 6.0±0.1mm and 3.0±0.2mm in thickness.
10mg tablets are pale pink, round and biconvex, with a score line in one side and dimensions 8.0±0.1mm and 3.5 ±0.2mm in thickness.
Pack sizes: 2, 3, 6, 12 or 18 tablets.
Not all pack sizes may be marketed.
Marketing Authorisation Holder:
This leaflet was last revised in 11/2022
1010072 - P7.3