The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet are: PL39699/0001, PL39699/0002.
Zyloric Tablets 100mg, 300mg
Zyloric 100 mg and 300 mg tablets
1. What Zyloric is and what it is used for
2. What you need to know before you take Zyloric
3. How to take Zyloric
4. Possible side effects
5. How to store Zyloric
6. Contents of the pack and other information
Zyloric tablets contain a medicine called allopurinol. It works by slowing down the speed of certain chemical reactions in your body to lower the level of uric acid in the blood and urine.
Zyloric is used:
If you are not sure, talk to your doctor or pharmacist before taking Zyloric.
Talk to your doctor or pharmacist before taking your medicine if:
Take special care with Zyloric:
Use in children is rarely indicated, except in some types of cancer (especially leukaemia) and certain enzyme disorders such as Lesch-Nyhan syndrome.
Tell your doctor or pharmacist if you are taking any of the following:
If aluminium hydroxide is taken concomitantly, allopurinol may have an attenuated effect. There should be an interval of at least 3 hours between taking both medicines.
With administration of allopurinol and cytostatics (e.g. cyclophosphamide, doxorubicin, bleomycin, procarbazine, alkyl halogenides), blood dyscrasias occur more frequently than when these active substances are administered alone.
Blood count monitoring should therefore be performed at regular intervals.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines obtained without a prescription, including herbal medicines. This is because Zyloric can affect the way some medicines work. Also some other medicines can affect the way Zyloric works.
Talk to your doctor before taking this medicine if you are pregnant, might become pregnant or are breast-feeding. Allopurinol is excreted in the human breast milk. Allopurinol during breastfeeding is not recommended.
You may feel drowsy, giddy or have problems with your coordination. If this happens, do not drive or use any tools or machines.
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Always take Zyloric exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
Take the tablet after food and swallow it with a glass of water.
The recommended dose ranges from 100 to 900 mg each day. You will usually start on a low dose, which will be increased if necessary.
If you are an older person or if you have reduced liver or kidney function, your doctor may prescribe a lower dose or to take it at longer intervals. If you have dialysis two or three times a week, your doctor may prescribe a dose of 300 or 400 mg which is to be taken straight after your dialysis.
Your doctor will usually start with a low dose of allopurinol (e.g. 100 mg/day), to reduce the risk of possible side effects. Your dose will be increased if necessary.
The usual dose ranges from 100 to 400 mg each day.
If you take more Zyloric than you should, contact a doctor or go to hospital straight away. Take the medicine pack with you. Signs of an overdose may include nausea, vomiting, diarrhoea and dizziness.
If you forget a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose.
Do not take a double dose to make up for a forgotten dose.
Do not stop taking your Zyloric without talking to your doctor.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with this medicine:
Uncommon (may affect less than 1 in 100 people)
If you have a hypersensitivity (allergic) reaction, stop taking Zyloric and see a doctor straight way. The signs may include:
Rare (may affect less than 1 in 1000 people)
Very rare (may affect up to 1 in 10,000 people)
Do not take any more tablets unless your doctor tells you to do so.
Common (may affect up to 1 in 10 people)
Uncommon (may affect up to 1 in 100 people)
Rare (may affect up to 1 in 1000 people)
Very rare (may affect up to 1 in 10,000 people)
Not known (cannot be estimated from available data):
Aseptic meningitis (inflammation of the membranes that surround the brain and spinal cord): symptoms include neck stiffness, headache, nausea, fever or consciousness clouding. Seek medical attention immediately if these occur.
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via: Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.
Zyloric tablets contain 100 or 300 mg allopurinol. Each 100 mg tablet is white to off-white, round and marked with a score line, Z1. Each 300 mg tablet is white to off-white, round and marked with a score line, Z3.
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Product name: Zyloric 100 mg tablets / Zyloric 300 mg tablets
Reference number: PL 39699/0001 / PL 39699/0002
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This leaflet was last revised in: December 2021.