Active ingredient
- perindopril arginine
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 05815/0036.
Coversyl Arginine
PATIENT INFORMATION LEAFLET
COVERSYL® ARGININE 2.5 mg Tablets
COVERSYL® ARGININE 5 mg Tablets
COVERSYL® ARGININE 10 mg Tablets
perindopril arginine
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
What is in this leaflet:
1. What Coversyl Arginine is and what it is used for
2. What you need to know before you take Coversyl Arginine
3. How to take Coversyl Arginine
4. Possible side effects
5. How to store Coversyl Arginine
6. Content of the pack and other information
1. What Coversyl Arginine is and what it is used for
Coversyl Arginine is an angiotensin converting enzyme (ACE) inhibitor.
These work by widening the blood vessels, which makes it easier for your heart to pump blood through them.
Coversyl arginine is used:
2. What you need to know before you take Coversyl Arginine
Do not take Coversyl Arginine
Warnings and precautions
If any of the following apply to you please talk to your doctor or pharmacist or nurse before taking Coversyl Arginine if you:
Angioedema
Angioedema (a severe allergic reaction with swelling of the face, lips, tongue or throat with difficulty in swallowing or breathing) has been reported in patients treated with ACE inhibitors, including Coversyl Arginine. This may occur at any time during treatment. If you develop such symptoms, you should stop taking Coversyl arginine and see a doctor immediately. See also section 4.
You must tell your doctor if you think you are (or might become) pregnant. Coversyl Arginine is not recommended in early pregnancy, and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage (see pregnancy section).
Children and adolescents
The use of perindopril in children and adolescents up to the age of 18 years is not recommended.
Other medicines and Coversyl Arginine
Please tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines.
Treatment with Coversyl Arginine can be affected by other medicines. Your doctor may need to change your dose and/or to take other precautions. These include:
Coversyl Arginine with food and drink
It is preferable to take Coversyl Arginine before a meal.
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Pregnancy
You must tell your doctor if you think you are (or might become) pregnant. Your doctor will normally advise you to stop taking Coversyl Arginine before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Coversyl Arginine. Coversyl Arginine is not recommended in early pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Breast-feeding
Tell your doctor if you are breast-feeding or about to start breast-feeding.
Coversyl Arginine is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is newborn, or was born prematurely.
Driving and using machines
Coversyl Arginine usually does not affect alertness but dizziness or weakness due to low blood pressure may occur in certain patients. If you are affected in this way, your ability to drive or to operate machinery may be impaired.
Coversyl Arginine contains lactose
Coversyl Arginine contains lactose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Coversyl Arginine contains sodium
Coversyl Arginine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially 'sodium-free'.
3. How to take Coversyl Arginine
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
Swallow your tablet with a glass of water, preferably at the same time each day, in the morning, before a meal. Your doctor will decide on the correct dose for you.
The recommended dosages are as follows:
High blood pressure: the usual starting and maintenance dose is 5 mg once daily. After one month, this can be increased to 10 mg once a day if required. 10 mg a day is the maximum recommended dose for high blood pressure.
If you are 65 or older, the usual starting dose is 2.5 mg once a day. After a month this can be increased to 5 mg once a day and then if necessary to 10 mg once daily.
Heart failure: the usual starting dose is 2.5 mg once daily. After two weeks, this can be increased to 5 mg once a day, which is the maximum recommended dose for heart failure.
Stable coronary artery disease: the usual starting dose is 5 mg once daily. After two weeks, this can be increased to 10 mg once daily, which is the maximum recommended dose in this indication.
If you are 65 or older, the usual starting dose is 2.5 mg once a day. After a week this can be increased to 5 mg once a day and after a further week to 10 mg once daily.
Use in children and adolescents
Use in children and adolescents is not recommended.
If you take more Coversyl Arginine than you should
If you take too many tablets, contact your nearest accident and emergency department or tell your doctor immediately. The most likely effect in case of overdose is low blood pressure which can make you feel dizzy or faint. If this happens, lying down with the legs raised can help.
If you forget to take Coversyl Arginine
It is important to take your medicine every day as regular treatment works better. However, if you forget to take a dose of Coversyl arginine, take the next dose at the usual time. Do not take a double dose to make up for a forgotten dose.
If you stop taking Coversyl Arginine
As the treatment with Coversyl Arginine is usually life-long, you should discuss with your doctor before stopping this medicinal product.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop taking the medicinal product and see a doctor immediately, if you experience any of the following side effects that can be serious:
Tell your doctor if you notice any of the following side effects:
Common (may affect up to 1 in 10 people):
Uncommon (may affect up to 1 in 100 people):
Rare (may affect up to 1 in 1000 people):
Very rare (may affect up to 1 in 10,000 people):
If you have these symptoms contact your doctor as soon as possible.
Frequency not known (cannot be estimated from available data): Discolouration, numbness and pain in fingers or toes (Raynaud's phenomenon).
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist or nurse.
This includes any possible side effects not listed in this leaflet.
You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine.
5. How to store Coversyl Arginine
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and bottle. The expiry date refers to the last day of that month.
Keep the bottle tightly closed in order to protect from moisture.
Do not throw away any medicine via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.
6. Content of the pack and other information
What Coversyl Arginine contains
What Coversyl arginine looks like and contents of the pack
Coversyl arginine 2.5 mg tablets are white, round, convex, film coated tablets.
Coversyl arginine 5 mg tablets are light-green, rod-shaped film-coated tablets engraved with on one face and scored on both edges. The tablet can be divided into equal halves.
Coversyl arginine 10 mg tablets are green, round, biconvex, film-coated tablets engraved with on one face and on the other face.
The tablets are available in box of 5, 10, 14, 20, 28, 30, 50, 60 (60 or 2 containers of 30), 84 (84 or 3 containers of 28), 90 (90 or 3 containers of 30), 100 (100 or 2 containers of 50), 120 (120 or 4 containers of 30) or 500 tablets (500 or 10 containers of 50).
Not all pack sizes may be marketed.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
Manufacturer
This leaflet was last revised in 10/2021
Sefton House, Sefton Park, Bells Hill, Stoke Poges, Slough, SL2 4JS, UK
+44 (0)1753 663456
+44 (0)1753 662744
+44 (0)1753 666409