The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL13621/0059.
Tobramycin 40 mg/1 ml solution for injection
Tobramycin Injection 40 mg/ml
1. What Tobramycin Injection is and what it is used for
2. What you need to know before you are given Tobramycin Injection
3. How you are given Tobramycin Injection
4. Possible side effects
5. How to store Tobramycin Injection
6. Contents of the pack and other information
Tobramycin Injection is a vial containing a solution for injection of the active ingredient tobramycin, which is an antibiotic. Tobramycin Injection is used to treat the following infections caused by micro-organisms that can be killed by tobramycin:
Tobramycin Injection must only be injected into a muscle or vein.
Tell your doctor if you:
Tobramycin Injection should be used with caution in premature and neonatal infants, and also in patients with extensive burns.
Tell your doctor if any of the above applies to you before this medicine is given to you.
Tell your doctor if you are taking, have recently taken or might take any other medicines.
In particular, the following medicines may interact with this medicine:
It may still be alright for you to be given Tobramycin Injection and your doctor will be able to decide what is suitable for you.
You should not have Tobramycin Injection if you are pregnant unless your doctor tells you to. Tobramycin may harm the unborn baby.
You should not have Tobramycin Injection if you are breast-feeding.
Ask your doctor or pharmacist for advice before taking any medicine.
Following rapid injection, Tobramycin Injection may cause muscle weakness or certain muscles not to work, and so may affect your ability to drive or use machines. If you are affected, you should not drive or operate heavy machinery until you feel it is safe to do so.
May rarely cause severe hypersensitivity reactions and bronchospasm (difficulty in breathing).
This medicine contains less than 1 mmol sodium (23 mg) per ml, that is to say essentially ‘sodium free’.
A doctor or nurse will give you Tobramycin Injection.
The recommended dose is:
Adults: 3mg per kg of body weight every 24 hours, given as 3 doses of 1mg per kg of body weight every 8 hours. If you have a serious bacterial infection, your doctor may use larger doses.
Children: 6 to 7.5mg per kg of body weight every 24 hours, given as 3 or 4 equal doses.
Premature or new-born babies: Up to 4mg per kg of body weight every 24 hours, given as 2 equal doses every 12 hours.
Kidney disorder: If you have a kidney disorder, your doctor will reduce your dose. This may happen during your treatment.
The usual length of treatment is 7 to 10 days. If you are treated for longer than this, your doctor will need to test your kidneys and ears because they may be damaged by the treatment.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Like all medicines, this medicine can cause side effects, although not everybody gets them.
All medicines can cause allergic reactions, although serious allergic reactions are very rare. Tell your doctor straight away if you get any sudden wheeziness, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body), or any of the following:
These are serious side effects, and you may only notice them after you stop treatment. You should see your doctor immediately.
If you notice changes in your urine or the number of times you need to urinate, tell your doctor straight away.
*(these conditions would be detected in a blood test carried out by a doctor).
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
Your doctor or pharmacist knows how to store Tobramycin Injection.
Keep this medicine out of the sight and reach of children.
Store below 25°C.
Do not use this medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use.These measures will help protect the environment.
Each 1ml solution contains 40mg of the active substance tobramycin.
The other ingredients are: phenol, sodium metabisulfite, disodium edetate, water for injection, sulfuric acid.
Tobramycin Injection is a clear, colourless solution provided in rubber stoppered glass vials in individual cartons.
This leaflet was last revised in May 2022.