• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Cequa is and what it is used for
2. What you need to know before you use Cequa
3. How to use Cequa
4. Possible side effects
5. How to store Cequa
6. Contents of the pack and other information

• if you are allergic to ciclosporin or any of the other ingredients of this medicine (listed in section 6).
• if you have had or have a cancer in or around your eye.
• if you have an eye infection.

Only use Cequa for dropping in your eye(s).

Talk to your doctor or pharmacist before using Cequa

• If you have had an eye infection by herpes virus that might have damaged the transparent from part of the eye (cornea),
• if you are taking any medicines containing steroids,
• if you are taking any medicines to treat glaucoma.

You should remove your contact lenses before using Cequa; you can insert them again 15 minutes after the administration of Cequa.

Cequa should not be used in children and adolescents below the age of 18 years.

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.

Talk to your doctor if you are using eye drops containing steroids, as these might increase the risk of side effects.

Cequa eye drops should be used at least 15 minutes after any other eye drops is used.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Cequa should not be used if you are pregnant.

If you could become pregnant you must use contraception while using this medicine.

Cequa is likely to be present in breast milk in very small amounts. If you are breast feeding talk to your doctor before using this medicine.

Your vision may be blurred immediately after using Cequa eye drops, solution in single-dose container. If this happens, wait until your vision clears before you drive or use machines.

This medicine contains 0.159 mg phosphates in each drop. If you suffer from severe damage to the clear layer at the front of the eye (the cornea), phosphates may cause in very rare cases cloudy patches on the cornea due to calcium build-up during treatment.

Follow these instructions carefully and ask your doctor or pharmacist if there is anything you do not understand.

• Wash your hands.
• If you wear contact lenses, take them out before using the drops; you can reuse them 15 minutes after you have administered the eye drops.
• Open the aluminium pouch, take one single-dose container out, and put the remaining single-dose containers back in the pouch
• Twist off the cap (picture 1).
• Pull down your lower eye lid (picture 2).
• Tilt your head back and look up to the ceiling.
• Gently squeeze one drop of the medicine onto your eye. Make sure you do not touch your eye with the tip of the single-dose container.
• Blink a few times to distribute the eye drop over your eye.
• After applying the drop, press a finger into the corner of your eye by the nose and close the eyelids gently for app. 2 minutes (picture 3) (this helps the local effect).
• If you use drops in both eyes, repeat the steps for your other eye.
• Discard the single-dose container as soon as you have used it, even if there is still some liquid left in it.
• The remaining single-dose containers should be kept in the aluminium pouch.

If a dropped missed the eye, try again.

If you use more Cequa than you should, rinse your eye with water. Do not put in any more drops until it is time for your next regular dose.

If you forget to use Cequa, continue with the next dose as planned.

Do not take a double dose to make up for a forgotten dose. Do not use more than one drop at a time in the effected eye (s).

If you stop using Cequa, discuss this with your doctor.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App store. By reporting side effects you can help provide more information on the safety of this medicine.

• The active substance is ciclosporin. One milliliter of Cequa contains 0.9 mg of ciclosporin.
• The other ingredients are: Macrogolglycerol hydroxystearate, octoxynol-40, sodium dihydrogen phosphate dihydrate (E339), disodium phosphate (E339), sodium chloride, povidone (E1201), hydrochloric acid (for pH adjustment) (E507), sodium hydroxide (for pH adjustment) (E524) and water for injection.

Cequa is a clear, colourless solution in single-dose container.

It is supplied in single-dose containers made of a low-density polyethylene (LDPE).

Each single-dose container contains 0.25 mL eye drops, solution.

The single dose containers are wrapped in a sealed polyfoil aluminium pouch.

Pack sizes: 60 single-dose containers.

Not all pack sizes may be marketed.