Active ingredient
- goserelin acetate
Legal Category
POM: Prescription only medicine
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet, the original can be viewed in PDF format using the link above.
The text only version may be available from RNIB in large print, Braille or audio CD. For further information call RNIB Medicine Leaflet Line on 0800 198 5000. The product code(s) for this leaflet is: PL 17901/0065.
Zoladex LA 10.8mg
Package leaflet: Information for the user
Zoladex LA® 10.8 mg Implant
goserelin
Read all of this leaflet carefully before you start using this medicine because it contains important information for you.
What is in this leaflet:
1. What Zoladex LA is and what it is used for
2. What you need to know before you use Zoladex LA
3. How to use Zoladex LA
4. Possible side effects
5. How to store Zoladex LA
6. Contents of the pack and other information
1. What Zoladex LA is and what it is used for
Zoladex LA contains a medicine called goserelin. This belongs to a group of medicines called ‘LHRH analogues’.
Zoladex LA is used to treat prostate cancer. It works by reducing the amount of ‘testosterone’ (a hormone) that is produced by your body. Zoladex LA is a long-acting form of Zoladex and it is given every 12 weeks.
2. What you need to know before you use Zoladex LA
Do not use Zoladex LA:
Do not have Zoladex LA if any of the above apply to you. If you are not sure, talk to your doctor, pharmacist or nurse before having Zoladex LA.
Warnings and precautions
Talk to your doctor, pharmacist or nurse before using Zoladex LA:
There have been reports of depression in patients taking Zoladex which may be severe. If you are taking Zoladex and develop depressed mood, inform your doctor.
Medicines of this type can cause a reduction in bone calcium (thinning of bones).
If you go into hospital, tell the medical staff that you are having Zoladex LA.
Children
Zoladex LA should not be given to children.
Other medicines and Zoladex LA
Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines. This includes medicines that you buy without a prescription and herbal medicines.
Zoladex LA might interfere with some medicines used to treat heart rhythm problems (e.g. quinidine, procainamide, amiodarone and sotalol) or might increase the risk of heart rhythm problems when used with some other drugs (e.g. methadone (used for pain relief and part of drug addiction detoxification), moxifloxacin (an antibiotic), antipsychotics used for serious mental illnesses).
Driving and using machines
Zoladex LA is not likely to affect you being able to drive or use any tools or machines.
3. How to use Zoladex LA
Your next appointment
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Allergic reactions:
These are rare. The symptoms can include sudden onset of:
If this happens to you, see a doctor straight away.
Injection site injury (including damage to blood vessels in the abdomen) has been reported following injection of Zoladex LA. In very rare cases this has caused severe bleeding. Contact your doctor immediately if you experience any of the following symptoms:
Other possible side effects:
Very common (may affect more than 1 in 10 people)
Common (may affect up to 1 in 10 people)
Uncommon (may affect up to 1 in 100 people)
Very rare (may affect up to 1 in 10,000 people)
Not known (frequency cannot be estimated from the available data)
Do not be concerned by this list of possible side effects. You may not get any of them.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Zoladex LA
6. Contents of the pack and other information
What Zoladex LA 10.8 mg Implant contains
The active substance is goserelin. Each Zoladex LA 10.8 mg Implant contains 10.8 mg of goserelin.
The other ingredient is lactide/glycolide copolymer which is an inactive substance.
What Zoladex LA 10.8 mg Implant looks like and contents of the pack
Zoladex LA 10.8 mg Implant comes as an implant (a very small pellet) in a pre-filled syringe, ready to be used by the doctor or nurse.
Zoladex LA 10.8 mg Implant is produced in packs of one implant (injection).
Marketing Authorisation Holder and Manufacturer
The Marketing Authorisation for Zoladex LA 10.8 mg Implant is held by
Zoladex LA 10.8 mg Implant is manufactured by
To listen to or request a copy of this leaflet in Braille, large print or audio please call, free of charge:
0800 198 5000 (UK only)
Please be ready to give the following information:
Product name Zoladex LA 10.8 mg Implant
Reference number 17901/0065
This is a service provided by the Royal National Institute of Blind People.
This leaflet was last revised in May 2015
© AstraZeneca 2015
Zoladex is a trade mark of the AstraZeneca group of companies.
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