What is a Patient Information Leaflet and why is it useful?

The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.

Below is a text only representation of the Patient Information Leaflet. The original can be viewed in PDF format using the link above.

The text only version may be available from RNIB in large print, Braille or audio CD. For further information call RNIB Medicine Leaflet Line on 0800 198 5000. The product code(s) for this leaflet are: EU/1/07/389/004, EU/1/07/389/005, EU/1/07/389/006, EU/1/07/389/007, EU/1/07/389/009, EU/1/07/389/010, EU/1/07/389/008.

ORENCIA 125 mg solution for injection (pre-filled syringe)

Package leaflet: Information for the patient

ORENCIA 125 mg solution for injection in pre-filled syringe

abatacept

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

What is in this leaflet

1. What ORENCIA is and what it is used for
2. What you need to know before you use ORENCIA
3. How to use ORENCIA
4. Possible side effects
5 How to store ORENCIA
6. Contents of the pack and other information

1. What ORENCIA is and what it is used for

ORENCIA contains the active substance abatacept, a protein produced in cell cultures. ORENCIA lessens the immune system's attack on normal tissues by interfering with the immune cells (called T lymphocytes) that contribute to the development of rheumatoid arthritis. ORENCIA selectively modulates the activation of T cells involved in the immune system's inflammatory response.

ORENCIA is used to treat Rheumatoid arthritis and Psoriatic Arthritis in adults.

Rheumatoid Arthritis

Rheumatoid arthritis is a long-term progressive systemic disease that, if untreated, can lead to serious consequences, such as joint destruction, increased disability and impairment of daily activities. In people with rheumatoid arthritis the body's own immune system attacks normal body tissues, leading to pain and swelling of the joints. This can cause joint damage. 24TRheumatoid arthritis (RA) affects everyone differently. In most people, joint symptoms develop gradually over several years. However, in some, RA may progress rapidly and yet other people may have RA for a limited period of time and then enter a period of remission. RA is usually a chronic (long-term), progressive disease. This means, even if you’re on treatment, whether or not you’re still having symptoms, RA could be continuing to damage your joints. By finding the right treatment plan for you, you may be able to slow down this disease process, which may help reduce long-term joint damage, as well as pain and fatigue and improve your overall quality of life.

ORENCIA is used to treat moderate to severe active rheumatoid arthritis when you do not respond well enough to treatment with other disease-modifying medicines or with another group of medicines called 'tumour necrosis factor (TNF) blockers'. It is used in combination with a medicine called methotrexate.

ORENCIA can also be used with methotrexate to treat highly active and progressive rheumatoid arthritis without previous methotrexate treatment.

ORENCIA is used to:

  • slow down the damage to your joints
  • improve your physical function

Psoriatic Arthritis

Psoriatic arthritis is an inflammatory disease of the joints, usually accompanied by psoriasis, an inflammatory disease of the skin. If you have active psoriatic arthritis you will first be given other medicines. If you do not respond well enough to these medicines, you may be given ORENCIA to:

  • Reduce the signs and symptoms of your disease.
  • Slow down the damage to your bones and joints.
  • Improve your physical function and your ability to do normal daily activities.

ORENCIA is used to treat psoriatic arthritis alone or in combination with methotrexate.

2. What you need to know before you use ORENCIA

Do not use ORENCIA

  • if you are allergic to abatacept or any of the other ingredients of this medicine (listed in section 6).
  • if you have a severe or uncontrolled infection, do not start treatment with ORENCIA. Having an infection could put you at risk of serious side effects from ORENCIA.

Warnings and precautions

Talk to your doctor, pharmacist or nurse:

  • if you experience allergic reactions such as chest tightness, wheezing, severe dizziness or lightheadedness, swelling or skin rash tell your doctor immediately.
  • if you have any kind of infection, including long-term or localised infection, if you often get infections or if you have symptoms of infection (e.g. fever, malaise, dental problems), it is important to tell your doctor. ORENCIA can lower your body's ability to fight infection and the treatment can make you more likely to get infections or make any infection you have worse.
  • if you have had tuberculosis (TB) or have symptoms of tuberculosis (persistent cough, weight loss, listlessness, mild fever) tell your doctor. Before you use ORENCIA, your doctor will examine you for tuberculosis or do a skin test.
  • if you have viral hepatitis tell your doctor. Before you use ORENCIA, your doctor may examine you for hepatitis.
  • if you have cancer, your doctor will decide if you can still be given ORENCIA.
  • if you recently had a vaccination or are planning to have one, tell your doctor. Some vaccines should not be given while you are receiving ORENCIA. Check with your doctor before you are given any vaccines. Certain vaccinations may cause infections from the vaccine. If you received ORENCIA while you were pregnant, your baby may be at a higher risk for getting such an infection for up to approximately 14 weeks after the last dose you received during pregnancy. It is important that you tell your baby’s doctors and other health care professionals about your ORENCIA use during your pregnancy so they can decide when your baby should receive any vaccine.

Your doctor may also do tests to examine your blood values.

ORENCIA and older people

ORENCIA can be used by people over 65 with no change in dose.

Children and adolescents

ORENCIA solution for injection has not been studied in children and adolescents under the age of 18 years. Therefore, ORENCIA solution for injection is not recommended for use in this patient population.

Other medicines and ORENCIA

Tell your doctor if you are taking, have recently taken or might take any other medicines.

ORENCIA should not be used with biological medicines for rheumatoid arthritis, including TNF-blockers like adalimumab, etanercept, and infliximab; there is not enough evidence to recommend its being given with anakinra and rituximab.

ORENCIA can be used with other medicines commonly used to treat rheumatoid arthritis, such as steroids or painkillers, including non-steroidal anti-inflammatories such as ibuprofen or diclofenac.

Ask your doctor or pharmacist for advice before taking any other medicine while using ORENCIA.

Pregnancy and breast-feeding

The effects of ORENCIA in pregnancy are not known, so do not use ORENCIA if you are pregnant unless your doctor specifically recommends it.

  • if you are a woman who could become pregnant, you must use reliable contraception (birth control) while using ORENCIA and up to 14 weeks after the last dose. Your doctor will advise you on suitable methods.
  • if you become pregnant while using ORENCIA, tell your doctor.
  • If you received ORENCIA during your pregnancy, your baby may have a higher risk for getting an infection. It is important that you tell your baby’s doctors and other health care professionals about your ORENCIA use during your pregnancy before the baby receives any vaccine (for more information see section on vaccination).

It is not known whether ORENCIA passes into human milk. You must stop breast-feeding if you are being treated with ORENCIA and for up to 14 weeks after the last dose.

Driving and using machines

The use of ORENCIA is not expected to affect the ability to drive or use machines. However, if you are feeling tired or unwell after receiving ORENCIA, you should not drive or operate any machinery.

ORENCIA contains sodium

This medicine contains less than 1 mmol sodium (23 mg) per dose, i.e. essentially 'sodium-free'.

3. How to use ORENCIA

Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.

ORENCIA solution for injection is injected under the skin (subcutaneous use).

Recommended dose

The recommended dose of ORENCIA for adults with rheumatoid arthritis or psoriatic arthritis is 125 mg given every week regardless of weight.

Your doctor may start your ORENCIA treatment with or without a one-time dose of powder for concentrate for solution for infusion (given to you into a vein, usually in your arm, over a period of 30 minutes). If a single intravenous dose is given to start the treatment, the first subcutaneous injection of ORENCIA should be given within a day of the intravenous infusion, followed by the weekly 125 mg subcutaneous injections.

If you are already on intravenous ORENCIA treatment and wish to transition to ORENCIA subcutaneous, you should receive a subcutaneous injection instead of your next intravenous infusion, followed by weekly subcutaneous injections of ORENCIA.

Your doctor will advise you on the duration of treatment and what other medicines, including other disease-modifying medicines, if any, you may continue to take while on ORENCIA.

At the start, your doctor or nurse may inject ORENCIA. However, you and your doctor may decide that you can inject ORENCIA yourself. In this case, you will get training on how to inject ORENCIA yourself.

Talk to your doctor if you have any questions about giving yourself an injection. You will find detailed "Instructions for preparing and giving a subcutaneous injection of ORENCIA" at the end of this leaflet.

If you use more ORENCIA than you should

If this happens, contact immediately your doctor who will monitor you for any signs or symptoms of side effects, and treat these symptoms if necessary.

If you forget to use ORENCIA

Keep track of your next dose. It is very important to use ORENCIA exactly as prescribed by your doctor. If you miss your dose within three days of when you are supposed to take it, take your dose as soon as you remember and then follow your original dosing schedule on your chosen day. If you miss your dose by more than three days, ask your doctor when to take your next dose.

If you stop using ORENCIA

The decision to stop using ORENCIA should be discussed with your doctor.

If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. The most common side effects with ORENCIA are infections of the upper airway (including infections of the nose and throat), headache and nausea, as listed below. ORENCIA can cause serious side effects, which may need treatment.

Possible serious side effects include serious infections, malignancies (cancer) and allergic reactions, as listed below.

Tell your doctor immediately if you notice any of the following:

  • severe rash, hives or other signs of allergic reaction
  • swollen face, hands or feet
  • trouble breathing or swallowing
  • fever, persistent cough, weight loss, listlessness

Tell your doctor as soon as possible if you notice any of the following:

  • feeling generally unwell, dental problems, burning sensation during urination, painful skin rash, painful skin blisters, coughing

The symptoms described above can be signs of the side effects listed below, all of which have been observed with ORENCIA in adult clinical trials:

List of side effects:

Very common (may affect more than 1 in 10 people):

  • infections of the upper airway (including infections of the nose, throat and sinuses).

Common (may affect up to 1 in 10 people):

  • infections of lungs, urinary infections, painful skin blisters (herpes), flu
  • headache, dizziness
  • high blood pressure
  • cough
  • abdominal pain, diarrhoea, nausea, upset stomach, mouth sores, vomiting
  • rash
  • fatigue, weakness, injection site reactions
  • abnormal liver function tests.

Uncommon (may affect up to 1 in 100 people):

  • tooth infection, nail fungal infection, infection in the muscles, blood stream infection, collection of pus under the skin, kidney infection, ear infection
  • low white blood cells count
  • skin cancer, skin warts
  • low blood platelet count
  • allergic reactions
  • depression, anxiety, sleep disturbance
  • migraine
  • numbness
  • dry eye, reduced vision
  • eye inflammation
  • palpitation, rapid heart rate, low heart rate
  • low blood pressure, hot flush, blood vessels inflammation, flushing
  • difficulty in breathing, wheezing, shortness of breath, acute worsening of a lung disease called chronic obstructive pulmonary disease (COPD)
  • throat tightness
  • rhinitis
  • increased tendency to bruise, dry skin, psoriasis, skin redness, excessive sweating, acne
  • hair loss, itching, hives
  • painful joints
  • pain in the extremities
  • absence of menstruation, excessive menses
  • flu-like illness, increased weight

Rare (may affect up to 1 in 1,000 people):

  • tuberculosis
  • inflammation of uterus, fallopian tubes and/or ovaries
  • gastrointestinal infection
  • cancer of white blood cells, lung cancer

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly (see details below). By reporting side effects you can help provide more information on the safety of this medicine.

Ireland

HPRA Pharmacovigilance
Earlsfort Terrace
IRL - Dublin 2
Tel: +353 1 6764971
Fax: +353 1 6762517
Website: www.hpra.ie
e-mail: medsafety@hpra.ie

United Kingdom

Yellow Card Scheme
Website: www.mhra.gov.uk/yellowcard

or search for MHRA Yellow Card in the Google Play or Apple App Store

5. How to store ORENCIA

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the label and the carton after EXP. The expiry date refers to the last day of that month.

Store in a refrigerator (2°C to 8°C). Do not freeze.

Store in the original package in order to protect from light.

Do not use this medicine if the liquid is cloudy or discoloured, or has large particles. The liquid should be clear to pale yellow.

Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.

6. Contents of the pack and other information

What ORENCIA contains

  • The active substance is abatacept.
  • Each pre-filled syringe contains 125 mg of abatacept in one mL.
  • The other ingredients are sucrose, poloxamer 188, sodium dihydrogen phosphate monohydrate, disodium phosphate anhydrous, and water for injections (see section 2 "ORENCIA contains sodium").

What ORENCIA looks like and contents of the pack

ORENCIA solution for injection (injection) is a clear, colourless to pale yellow solution.

ORENCIA is available in the following presentations:

  • packs of 1, or 4 pre-filled syringes and multipack containing 12 pre-filled syringes (3 packs of 4).
  • packs of 1, 3, or 4 pre-filled syringes with needle guard and multipack containing 12 pre-filled syringes with needle guard (3 packs of 4).

Not all pack sizes may be marketed.

Marketing Authorisation Holder

Bristol-Myers Squibb Pharma EEIG
Plaza 254
Blanchardstown Corporate Park 2
Dublin 15
D15 T867
Ireland

Manufacturer

Bristol-Myers Squibb S.R.L.
Contrada Fontana del Ceraso
I-03012 Anagni-Frosinone
Italy

Swords Laboratories t/a Bristol-Myers Squibb Cruiserath Biologics
Cruiserath Road
Mulhuddart
Dublin 15
Ireland

For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder:

United Kingdom
Bristol-Myers Squibb Pharmaceuticals Ltd
Tel: + 44 (0800) 731 1736

This leaflet was last revised in February 2019

Other sources of information

Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu.

Instructions for preparing and giving a subcutaneous injection of ORENCIA:

Please read these instructions carefully and follow them step by step.

You will be trained by your doctor or nurse on how to self-inject ORENCIA using the pre-filled syringe.

Don’t try to self-inject until you are sure that you understand how to prepare and give the injection. After proper training, you can give the injection to yourself, or it can be given by another person, for example a family member or friend.

Before you start - some Do's and Don'ts

Do

  • Always handle the ORENCIA syringe carefully, especially when you are around other people, and children.
  • Always hold the syringe by its body.
  • Store unused syringes in the refrigerator in the original carton.
  • Have your additional injection supplies ready before you inject.
    • Supplies checklist: alcohol swabs, cotton ball or gauze, adhesive plaster, Sharps container. Sharps containers are special puncture-resistant disposal bins that can be bought at many retail outlets.

Don’t

  • Don’t remove the needle cover (cap) until you are ready to inject.
  • Don’t pull back on the plunger at any time.
  • Don’t shake the syringe, as this may damage the ORENCIA medicine.
  • DON’T recap the needle.

STEP 1: Get the syringe ready

A. Check the expiry date and batch number on the carton

  • The expiry date can be found on the ORENCIA carton and on each syringe.
  • If the expiry date has passed, do not use the syringes. Contact your doctor or pharmacist for assistance.

B. Let the syringe warm up

  • Find a comfortable space with a clean, flat, working surface.
  • Remove the syringe from the refrigerator. Keep any remaining unused syringes in their original carton, in the refrigerator.
  • Check that the expiry date and batch number match the ones on the carton.
  • Inspect the syringe for obvious flaws, but don't remove the needle cover.
  • Allow the syringe to rest at room temperature for 30 to 60 minutes before you inject.
    • Don't speed the warming process in any way, such as using the microwave or placing the syringe in warm water.

C. Check the liquid in the syringe

  • Hold the syringe by its body, with the covered needle pointing down.
  • Look at the liquid in the syringe (Figure 2). The liquid should be clear to pale yellow.
    • Don't inject if the liquid is cloudy or discoloured, or has visible particles.
  • It is normal to see an air bubble, and there is no reason to remove it. All contents of the syringe should be injected.

D. Gather your additional supplies and keep them within easy reach.

E. Wash your hands thoroughly with soap and warm water.

STEP 2: Choose and prepare your injection site

Have the syringe ready for use immediately after you have prepared your injection site.

A. Choose an area of your body for the injection (injection site)

  • You can use:
    • the front of your thigh
    • your abdomen, except for the 5 cm area around the navel (Figure 3).
  • Choose a different injection site for each new injection. You may use the same thigh for weekly injections, as long as each injection site is approximately 2.5 cm away from where you last injected.
  • Don't inject into areas where your skin is tender, bruised, red, scaly, or hard. Avoid any areas with scars or stretch marks.

B. Prepare your injection site

  • Wipe your injection site with an alcohol swab in a circular motion.
  • Let your skin dry before injecting.
    • Don't touch your injection site again before giving the injection.
    • Don’t fan or blow on the clean area.

STEP 3: Inject ORENCIA

A. Remove the needle cover (cap) only when you are ready to administer the injection.

  • Hold the syringe by its body in one hand, and pull the needle cover straight off with your other hand (Figure 4).

There may be a small air bubble in the liquid in the syringe. There is no need to remove the air bubble.

You may notice a drop of fluid leaving the needle. This is normal and will not affect your dose.

  • Don’t touch the plunger while you remove the needle cover.
  • Don’t remove the needle cover until you are ready to inject ORENCIA.
  • Don’t touch the needle or let it touch any surfaces.
  • Don’t use the syringe if it is dropped without the needle cover in place.
  • Don’t put the needle cover back on the needle once removed.
  • Don’t use the syringe if there are visible signs of needle damage or bending.

B. Position the syringe and inject ORENCIA

  • Hold the syringe by its body in one hand between your thumb and index finger (Figure 5).
    • Don't press on the plunger head until you begin your injection.
    • Don't pull back on the plunger at any time.
  • Using your other hand, gently pinch the area of skin you cleaned. Hold it firmly.
  • Insert the needle with a quick motion into the pinched skin at a 45° angle (Figure 5).
  • Use your thumb to push the plunger down, pressing firmly until the plunger will go no further, and all of the medicine has been injected (Figure 6).
  • Remove the needle from the skin and let go of the surrounding skin.
    • DON’T recap the needle.
  • Press a cotton ball over the injection site and hold for 10 seconds.
    • Don’t rub the injection site. Slight bleeding is normal.
  • If needed, you may apply a small adhesive plaster to the injection site.

STEP 4: Dispose of the syringe and keep a record

A. Dispose of the used syringe in a Sharps container.

  • Ask your doctor, nurse, or pharmacist about national and local laws regarding the proper disposal of medical products that contain needles.
  • Always keep your Sharps container out of reach of children and animals.
  • Don’t throw away used syringes in your household rubbish or recycling bins.

B. Keep a record of your injection

  • Write down the date, time, and specific part of your body where you injected yourself. It may also be helpful to write down any questions or concerns about the injection so you can ask your doctor, nurse or pharmacist.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

Instructions for preparing and giving a subcutaneous injection of ORENCIA:

Please read these instructions carefully and follow them step by step.

You will be trained by your doctor or nurse on how to self-inject ORENCIA using the pre-filled syringe with needle guard.

Don't try to self-inject until you are sure that you understand how to prepare and give the injection. After proper training, you can give the injection to yourself, or it can be given by another person, for example a family member or friend.

Before you start - some Do's and Don'ts

Do

  • Always handle the ORENCIA syringe carefully, especially when you are around other people, and children.
  • Always hold the syringe by its body.
  • Store unused syringes in the refrigerator in the original carton.
  • Have your additional injection supplies ready before you inject.
    • Supplies checklist: alcohol swabs, cotton ball or gauze, adhesive plaster, Sharps container. Sharps containers are special puncture-resistant disposal bins that can be bought at many retail outlets.

Don’t

  • Don’t pull by the plunger or the needle cover when removing the syringe from the tray.
  • Don’t remove the needle cover until you are ready to inject.
  • Don’t pull back on the plunger at any time.
  • Don’t shake the syringe, as this may damage the ORENCIA medicine.
  • DON’T recap the needle.

STEP 1: Get the syringe ready

A. Check the expiry date and batch number on the carton

  • The expiry date can be found on the ORENCIA carton and on each syringe.
  • If the expiry date has passed, do not use the syringes. Contact your doctor or pharmacist for assistance.

B. Let the syringe warm up

  • Find a comfortable space with a clean, flat working surface.
  • Remove the syringe from the refrigerator. Keep any remaining unused syringes in their original carton, in the refrigerator.
  • To remove the syringe from the package, hold it by its body as indicated by the arrows in the tray.
    • Don't hold it by the plunger.
  • Check that the expiry date and batch number match the ones on the carton.
  • Inspect the syringe for obvious flaws, but don't remove the needle cover.
  • Allow the syringe to rest at room temperature for 30 to 60 minutes before you inject.
    • Don't speed the warming process in any way, such as using the microwave or placing the syringe in warm water.

C. Check the liquid in the pre-filled syringe

  • Hold the syringe by its body with the covered needle pointing down.
  • Look at the liquid in the syringe window (Figure 2). The liquid should be clear to pale yellow.
    • Don't inject if the liquid is cloudy or discoloured, or has visible particles.
  • It is normal to see an air bubble, and there is no reason to remove it. All contents of the syringe should be injected.

D. Gather your additional supplies and keep them within easy reach.

E. Wash your hands thoroughly with soap and warm water.

STEP 2: Choose and prepare your injection site

Have the syringe ready for use immediately after you have prepared your injection site.

A. Choose an area of your body for the injection (injection site)

  • You can use:
    • the front of your thigh
    • your abdomen, except for the 5 cm area around the navel (Figure 3).
  • Choose a different injection site for each new injection. You may use the same thigh for weekly injections, as long as each injection site is approximately 2.5 cm away from where you last injected.
    • Don't inject into areas where your skin is tender, bruised, red, scaly, or hard. Avoid any areas with scars or stretch marks.

B. Prepare your injection site

  • Wipe your injection site with an alcohol swab in a circular motion.
  • Let your skin dry before injecting.
    • Don't touch your injection site again before giving the injection.
    • Don't fan or blow on the clean area.

STEP 3: Inject ORENCIA

A. Remove the needle cover (cap) only when you are ready to administer the injection.

  • Hold the syringe by its body in one hand and pull the needle cover straight off with your other hand (Figure 4).

There may be a small air bubble in the liquid in the syringe. There is no need to remove the air bubble.

You may notice a drop of fluid leaving the needle. This is normal and will not affect your dose.

  • Don’t touch the plunger while you remove the needle cover.
  • Don’t remove the needle cover until you are ready to inject ORENCIA.
  • Don’t touch the needle or let it touch any surfaces.
  • Don’t use the syringe if it is dropped without the needle cover in place.
  • Don’t put the needle cover back on the needle once removed.
  • Don’t use the syringe if there are visible signs of needle damage or bending.

B. Position the syringe and inject ORENCIA

  • Hold the syringe by its body in one hand between your thumb and index finger (Figure 5).
    • Don't press on the plunger head until you begin your injection.
    • Don't pull back on the plunger at any time.
  • Using your other hand, gently pinch the area of skin you cleaned. Hold it firmly.
  • Insert the needle with a quick motion into the pinched skin at a 45° angle (Figure 5).
  • Use your thumb to push the plunger down, pressing firmly until the plunger will go no further, and all of the medicine has been injected (Figure 6).
  • When the plunger is pushed in as far as it will go, keep your thumb on the plunger head.
  • Slowly relax the pressure of your thumb on the plunger head and allow it to move your thumb back upwards. This lets the empty syringe move up until the whole needle is covered by the needle guard (Figure 7).
  • Once the needle is completely covered by the needle guard, let go of the surrounding skin. Remove the syringe.
  • Press a cotton ball over the injection site and hold for 10 seconds.
    • Don’t rub the injection site. Slight bleeding is normal.
  • If needed, you may apply a small adhesive plaster to the injection site.

STEP 4: Dispose of the syringe and keep a record

A. Dispose of the used syringe in a Sharps container.

  • Ask your doctor, nurse, or pharmacist about national and local laws regarding the proper disposal of medical products that contain needles.
  • Always keep your Sharps container out of reach of children and animals.
  • Don’t throw away used syringes in your household rubbish or recycling bins.

B. Keep a record of your injection

  • Write down the date, time, and specific part of your body where you injected yourself. It may also be helpful to write down any questions or concerns about the injection so you can ask your doctor, nurse, or pharmacist.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.