This information is intended for use by health professionals
Acidex, Compound Alginate Oral Suspension Heartburn
Asda Heartburn and Indigestion Liquid
Boots Heartburn Relief Aniseed Flavour
Galpharm Heartburn and Indigestion Relief Oral Suspension
LloydsPharmacy Heartburn and Indigestion Liquid
Peptac Liquid, Heartburn and Indigestion Liquid
Heartburn and Indigestion relief
Sainsbury's Heartburn and Indigestion Liquid
Superdrug Acid Indigestion and Heartburn Relief Suspension
Wilkinson Heartburn and Indigestion Liquid
Essential Waitrose Heartburn and Indigestion Oral Suspension
Morrisons Heartburn and Indigestion Oral Suspension
Numark Heartburn and Indigestion Oral Suspension
Healthpoint Heartburn and Indigestion Oral Suspension
Each 5 ml contains:
Sodium Bicarbonate BP
Sodium Alginate BP
Calcium Carbonate BP
Also contains parahydroxybenzoates. For a full list of excipients, see section 6.1
Aniseed Flavoured Pink Suspension
Acidex Compound Alginate Oral Suspension Heartburn and Indigestion Liquid alleviates the painful conditions resulting from the reflux of gastric acid and bile into the oesophagus by suppressing the reflux itself. It is indicated in heartburn, including heartburn of pregnancy, dyspepsia associated with gastric reflux, hiatus hernia, reflux oesophagitis, regurgitation and all cases of epigastric and retrosternal distress where the underlying cause is gastric reflux.
For oral use
Adults and children over 12 years:
Two to four 5 ml spoonfuls.
Children 6 - 12 years:
One to two 5 ml spoonfuls
Not recommended in children under six years of age.
Doses should be taken after meals and at bedtime.
There are no specific contraindications.
1. Each 10 ml dose of Acidex Compound Alginate Oral Suspension Heartburn and Indigestion Liquid contains about 6 mmoles of sodium and therefore care should be exercised in patients on a sodium restricted diet.
2. Acidex Compound Alginate Oral Suspension Heartburn and Indigestion Liquid should not be taken within 1 to 2 hours of taking other medicines by mouth, or for more than 2 weeks if symptoms persist.
3. Acidex Compound Alginate Oral Suspension Heartburn and Indigestion Liquid should not be used by patients allergic to any of its constituents.
4. Parahydroxybenzoates (E214 and E216): may cause allergic reactions (possibly delayed).
1. Antacids may interact with other drugs as they alter the gastric pH which may affect dissolution, solubility or ionization of the other drug. Antacids reduce the absorption of certain drugs from the following groups: ACE Inhibitors, Analgesics, Antibacterials, Antiepileptics, Antifungals, Antimalarials, Antipsychotics, Bisphosphonates, Penicillamine.
2. Antacids may increase the pH of the urine and affect the rate of drug elimination. Excretion of basic drugs is decreased whereas acidic drugs are eliminated more rapidly.
3. Due to effects at the renal level sodium bicarbonate may reduce plasma lithium levels and increase plasma quinidine levels.
Acidex Compound Alginate Oral Suspension Heartburn and Indigestion Liquid is indicated for heartburn of pregnancy and may be used during lactation.
For Acidex Compound Alginate Oral Suspension Heartburn and Indigestion Liquid no clinical data on exposed pregnancies are available. Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/foetal development, parturition or postnatal development. To date, no other relevant epidemiological data are available.
Caution should be exercised when prescribing to pregnant women.
There are no effects on ability to drive or operate machinery.
Constipation, flatulence, stomach cramps or belching may occasionally occur.
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme Website :www.mhra.gov.uk/yellowcard
As Acidex Compound Alginate Oral Suspension Heartburn and Indigestion Liquid's mode of action is physical, overdosage in terms of the alginate content is virtually no hazard. The only consequence is abdominal distension which is best treated conservatively. The relatively low concentrations of sodium and calcium carbonate in Acidex Compound Alginate Oral Suspension Heartburn and Indigestion Liquid would also make serious consequences from overdosage very unlikely.
When taken after a meal Sodium Alginate forms a rigid raft of alginic acid in the stomach reducing gastric reflux. This raft formed is maintained in the stomach for two hours. Sodium bicarbonate reacts with gastric acid to produce carbon dioxide which is retained in the gel and allows the raft to rise to the surface of the gastric contents. Calcium ions from calcium carbonate link the alginic acid molecules and strengthen the raft.
Alginic acid is not absorbed into the systemic circulation.
There is no Preclinical Safety Data.
Carbomer (Carbopol 974P)
Ethyl parahydroxybenzoate (E214)
Propyl parahydroxybenzoate (E216)
Erythrosine Colour (E127)
Star Anise Oil
24 months - amber glass bottles
18 months - HDPE bottles
15 months PET bottles
Do not store above 25°C. Do not refrigerate.
Pharmaceutical Grade III amber glass bottles with pilfer proof caps and tamper evident screw caps.
High density polyethylene bottles with tamper evident screw caps.
PET bottle with tamper evident screw caps.
Pack sizes: 50ml, 100ml, 150ml, 200ml, 250ml, 300ml and 500ml.
Pinewood Laboratories Limited,