Boots Paracetamol Extra 500 mg/65 mg Tablets

This medicine is available without prescription to treat minor conditions. However, you still need to take it carefully to get the best results from it.

• Keep this leaflet, you may need to read it again
• Ask your pharmacist if you need more information or advice

• If you are under 12 years old
• If you are allergic to any of the ingredients (see “What is in this medicine”)
• If you have high blood pressure or an irregular heart beat
• If you have an anxiety disorder
• If you take any of these medicines:
  • Medicines for high blood pressure
  • Medicines for depression, including monoamine oxidase inhibitors, or stimulant medicines
  • Medicines for anxiety, or medicines that make you feel sleepy
  • Disulfiram (for alcoholism)
  • Decongestants containing ephedrine
  • Theophylline (for breathing problems)
  • Thyroxine (for thyroid problems)
• If you are pregnant or breastfeeding

• If you have severe kidney or liver problems (including alcoholic liver disease)

This medicine contains caffeine, which is also found in tea, coffee, chocolate and some fizzy drinks such as cola. Taking too much caffeine can cause difficulty sleeping, shaking or a thumping sensation in the chest (palpitations).

You must not drink tea, coffee, chocolate or fizzy drinks containing caffeine if you need to take this medicine.

Do not drink alcohol (wine, beers, spirits) whilst taking this medicine.

If you need to have tests for your heart, stop taking this medicine 24 hours before the test. It may affect the results.

This medicine contains paracetamol.

Do not take with any other paracetamol-containing products.

Before you take these tablets, make sure that you tell your pharmacist about ANY other medicines you might be using at the same time, particularly the following:

• Other medicines containing caffeine
• Phenytoin (for epilepsy)
• Methoxsalen (for psoriasis)
• Pipemidic acid (for infections)
• Domperidone or metoclopramide (for feeling sick or being sick)
• Colestyramine (for reducing blood fat levels)
• Warfarin or other blood thinners – you can take occasional amounts of this medicine, but talk to your doctor first before you take it on a regular basis
• Flucloxacillin (antibiotic), due to a serious risk of blood and fluid abnormality (high anion gap metabolic acidosis) that must have urgent treatment and which may occur particularly in case of severe renal impairment, sepsis (when bacteria and their toxins circulate in the blood leading to organ damage), malnutrition, chronic alcoholism, and if the maximum daily doses of paracetamol are used

If you are unsure about interactions with any other medicines, talk to your pharmacist. This includes medicines prescribed by your doctor and medicine you have bought for yourself, including herbal and homeopathic remedies.

• Difficulty in breathing, swelling of the face, neck, tongue or throat (severe allergic reactions)
• Allergic skin reactions (which can sometimes be severe and include peeling, blistering and lesions of the skin)
• Signs of caffeine sensitivity including
  • Tremor, difficulty sleeping, dizziness, nervousness, restlessness, irritability, anxiety
  • Headache, ringing in the ears
  • Fast or irregular heartbeat, rapid breathing
  • Frequent need to pass urine, stomach upset

Breathing problems are more likely if you have asthma and have experienced them before when you have taken other medicines such as aspirin and ibuprofen (non-steroidal anti-inflammatory medicines).

• Other allergic reactions (e.g. skin rash)
• Yellowing of the skin or eyes, pale stools or upper abdominal pain (these may be signs of liver problems)
• Unusual bruising, or infections such as sore throats – this may be a sign of very rare changes in the blood
  If you have taken this medicine for a long time you may get a headache, feel tired, or feel sleepy for up to a week after you stop taking the tablets.
• Very rare cases of serious skin reactions have been reported. This may include peeling, blistering and lesions of the skin.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.

White capsule shaped tablets with no marks and plain on both sides.

This pack contains 16 or 32 tablets.