Phenylephrine Injection BP 10 mg/ml

• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor, pharmacist or nurse.
• If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Phenylephrine Injection is and what it is used for
2. What you need to know before you are given Phenylephrine Injection
3. How Phenylephrine Injection is given to you
4. Possible side effects
5. How to store Phenylephrine Injection
6. Contents of the pack and other information

• if you are allergic to phenylephrine hydrochloride or any of the other ingredients of this medicine (listed in section 6)
• if you are taking a group of medicines called monoamine oxidase inhibitors (MAOIs) or have stopped taking them within the last 14 days
• if you have high blood pressure, or an overactive thyroid (hyperthyroidism)
• if you have prostatic enlargement
• if the anterior part (anterior chamber) of your eye is shallow
• if you have a history of acute increase of eye pressure (acute narrow angle glaucoma).

Talk to your doctor, pharmacist or nurse before you are given Phenylephrine Injection

• If you have heart conditions such as the following: ischaemic heart disease, arrhythmia, angina pectoris, occlusive vascular disease, high blood pressure or aneurysms
• If you have diabetes mellitus, diabetic autonomic neuropathy (a complication of diabetes mellitus)

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Tell your doctor if you have taken antidepressants (either currently or within the last 14 days)

Tell your doctor if you have taken tablets for heart problems or high blood pressure.

Phenylephrine may interact with some drugs used as general anaesthetics, but your doctor will be fully prepared to deal with this should it occur.

Phenylephrine may interact with a drug used to treat attention-deficit hyperactivity disorder (ADHD) called atomoxetine.

Phenylephrine may also interact with drugs called antimuscarinics (e.g. atropine.)

Lithium (a drug used for depression or aggression) may effect how phenylephrine works.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

The safety of phenylephrine during pregnancy and breast-feeding has not been established.

Phenylephrine Injection should not affect your ability to drive. As with all medicines, if you feel unwell you must speak to your doctor or nurse before driving or operating machinery.

This medicine contains less than 1 mmol sodium (23 mg) per ml, that is to say essentially ‘sodium-free’.

The recommended dose is 100 micrograms per kilogram of body weight, injected into a muscle or just under the skin.

It is unlikely that you will be given too much Phenylephrine Injection; however should an overdose occur the doctor will treat any symptoms that follow. Symptoms of overdose include headache, feeling sick, high blood pressure, a fast or irregular heart beat, confusion, hallucinations and fits..

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine.

• The active substance is phenylephrine hydrochloride. Each 1 ml ampoule contains 10 mg of the active substance phenylephrine hydrochloride.
• The other ingredients are sodium hydroxide solution, hydrochloric acid and water for injections.

Phenylephrine Injection is a clear, colourless or slightly brown solution. It is available in 1 ml glass ampoules, in packs containing either 6 or 10 ampoules. Not all pack sizes may be marketed.

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This leaflet does not contain the complete information about your medicine. If you have any questions or are not sure about anything, ask your doctor who has access to additional information.