This information is intended for use by health professionals
Conotrane cream contains the active substances benzalkonium chloride (0.1% w/w) and dimeticone (22.0% w/w).
Excipient(s) with known effect: cetostearyl alcohol
For the full list of excipients, see section 6.1.
A smooth, white cream for topical administration.
Conotrane is used for protection of the skin from moisture, irritants, chafing and contamination with bacteria or yeasts.
It may be used in situations such as in the prevention/treatment of napkin rash, the prevention of pressure sores and in the management of incontinence.
For cutaneous use. The cream should be applied to the affected area(s) several times a day, as necessary or after every napkin change.
Hypersensitivity to the active substance(s) or to any of the excipients listed in section 6.1.
Cetostearyl alcohol may cause local skin reactions (e.g. contact dermatitis).
Conotrane contains paraffin. Instruct patients not to smoke or go near naked flames - risk of severe burns. Fabric (clothing, bedding, dressings etc) that has been in contact with this product burns more easily and is a serious fire hazard. Washing clothing and bedding may reduce product build-up but not totally remove it.
Benzalkonium chloride may irritate the skin.
No interaction studies have been performed.
There are no or limited amount of data from the use of Conotrane in pregnant women. It is unknown whether benzalkonium chloride, dimeticone or their metabolites are excreted in human milk.
If used during breast-feeding Conotrane should not be applied to the breasts to avoid accidental ingestion by the infant.
Local hypersensitivity to benzalkonium chloride is rare.
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.
Pharmacotherapeutic group: Antiseptics and disinfectants. ATC code: D08A J01
This is a remedy suitable for both prescription and for self-medication. It is a cream for topical application containing dimeticone and benzalkonium chloride. The dimeticone is water repellent allowing transpiration of water vapour from the skin. The benzalkonium chloride is a quaternary ammonium compound, active against bacteria and yeasts.
Macrogol cetostearyl ether
White soft paraffin
Light liquid paraffin
Potassium dihydrogen orthophosphate
Do not store above 25°C.
(i) 7 g, 15 g, 50 g and 100 g in white LDPE tubes.
(ii) 500 g white polypropylene jar with HDPE tamper evident lid.
Not all pack sizes may be marketed.
Karo Pharma AB
103 24 Stockholm
Date of first authorisation: 01 July 1998
Date of latest renewal: 16 July 2003
24 February 2021.