- doxycycline hyclate
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL 30464/0060 .
Doxycycline 50mg Capsules
PATIENT INFORMATION LEAFLET
DOXYCYCLINE 50mg CAPSULES
Please read this leaflet carefully before you start to take this medicine.
IN THIS LEAFLET
1. What your medicine is and what it is used for
2. What you need to know before you take your medicine
3. How to take your medicine
4. Possible side effects
5. How to store your medicine
6. Contents of the pack and other information
1. WHAT YOUR MEDICINE IS AND WHAT IT IS USED FOR
The name of your medicine is Doxycycline 50mg Capsules. It belongs to a group of medicines called tetracycline antibiotics. It may be used to treat a wide range of infections caused by bacteria, these include:
Doxycycline capsules are also used to prevent certain infections developing such as scrub typhus, travellers’ diarrhoea, malaria and leptospirosis (a bacterial infection caused by exposure to bacteria in fresh water contaminated by animal urine).
2. WHAT YOU NEED TO KNOW BEFORE YOU TAKE YOUR MEDICINE
Do not take your medicine and tell your doctor, if you:
You should not use Doxycycline during periods of tooth development (pregnancy, infancy or in children below 8 years old) as such use may lead to permanent discolouration (yellow-grey-brown) or affect the proper growth of the teeth.
There may be circumstances (e.g. severe or life-threatening conditions), where your physician may decide that the benefits outweigh this risk in children below 8 years and doxycycline should be prescribed.
Important information about one of the ingredients in this medicine
Doxycycline 50mg Capsules contain sucrose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Take special care with your medicine
You should let your doctor know and ask their advice, if you:
Taking other medication
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Especially:
Alcohol may reduce the effect of your medicine. It is therefore advisable to avoid drinking any alcohol.
Pregnancy and breast-feeding
If you are pregnant, planning to become pregnant or are breast-feeding ask your doctor or pharmacist for advice before taking any medicine as Doxycycline could harm the baby.
Driving and using machines
Do not drive or use machines if you suffer from visual disturbances such as blurring of vision while taking Doxycycline.
3. HOW TO TAKE YOUR MEDICINE
Always take your medicine exactly as your doctor has instructed you. You should check with your doctor or pharmacist, if you are unsure. Do not take more than your doctor has recommended.
Your medicine should be taken by mouth as follows:
Adults and children aged 12 years to less than 18 years:
200mg on the first day, then 100mg daily. The length of treatment is dependent on the infection being treated.
Respiratory, urinary tract, ophthalmic and other infections
The usual dose is 200mg on the first day as a single dose or two 100mg doses, followed by 100mg daily. For severe infections your doctor may increase the dose to 200mg a day. The duration of treatment is dependent on the infection being treated.
50mg daily for 6-12 weeks, with food or fluid.
Sexually transmitted diseases
100mg twice daily for 7-10 days.
Primary and secondary syphilis
300mg daily in divided doses for at least 10 days.
Fevers associated with louse or tick bites
Single dose of 100mg or 200mg depending on severity.
Treatment of malaria, when chloroquine is not effective
200mg daily for at least 7 days.
Prevention of malaria
100mg daily for 1-2 days before travelling until 4 weeks after returning.
Prevention of scrub typhus
Single dose of 200mg.
Prevention of travellers’ diarrhoea
100mg twice daily on the first day of travel, followed by 100mg daily throughout the stay in the area. If you are planning to take these capsules for more than 21 days, please consult your doctor.
Prevention of leptospirosis
200mg once each week during the stay in the area; 200mg on completion of the trip. If you are planning to take these capsules for more than 21 days, please consult your doctor.
Doctors may prescribe different doses to these depending on the infection being treated. Check with your doctor if you are not sure why you have been prescribed the medicine.
The label on the pack will tell you what dose YOU should take, how often and for how long to take it.
If you are still not sure, ask your doctor or pharmacist.
Children aged 8 years to less than 12 years:
Doxycycline for the treatment of acute infections in children aged 8 years to less than 12 years should be used in situations where other drugs are not available or are not likely to be effective. In such circumstances, the usual doses are:
For children 45kg or less:
First day: 4.4mg for each kg of bodyweight (in single or 2 divided doses) then 2.2mg for each kg of bodyweight (in single or 2 divided doses) from the second day. The length of treatment is dependent on the infection being treated.
In more severe infections, up to 4.4mg for each kg of bodyweight should be given throughout treatment.
For children over 45kg:
Dose administered for adults should be used; 200mg on the first day, then 100mg daily. The length of treatment is dependent on the infection being treated.
Overdose: If you take more of your medicine than you should
If you (or someone else) swallow a lot of capsules at the same time, or you think a child may have swallowed any, contact your nearest hospital casualty department or tell your doctor immediately.
If you forget to take your medicine
Do not take a double dose to make up for a forgotten dose. If you forget to take a dose take it as soon as you remember it and then take the next dose at the right time.
If you stop taking your medicine
Do not stop treatment early as your infection may return if you do not finish the course of capsules.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Doxycycline can cause side effects, although not everybody gets them.
Stop taking your medicine and tell your doctor immediately, or go to accident and emergency if you notice any of the following symptoms. Although the symptoms are very rare, they may be severe.
If you experience any of the side effects listed below, tell your doctor as soon as possible:
The side effects listed below may go away during treatment as your body adjusts to the medicine. Tell your doctor if any of these side effects continue to bother you:
Common: may affect up to 1 in 10 people
Uncommon: may affect up to 1 in 100 people
Rare: may affect up to 1 in 1,000 people
Not known: frequency cannot be estimated from the available data
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the yellow card scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. HOW TO STORE YOUR MEDICINE
Do not use your medicine after the expiry date shown on the blister and carton. The expiry date refers to the last day of that month.
KEEP OUT OF THE SIGHT AND REACH OF CHILDREN.
Store below 25°C. Store in the original package.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. CONTENTS OF THE PACK AND OTHER INFORMATION
What your medicine contains
The active substance (the ingredient that makes the capsules work) is doxycycline hyclate.
The other ingredients in the capsule are sucrose, maize (corn) starch, water, crospovidone, Basic Butylated Methacrylate Copolymer (Eudragit E100) and purified talc.
The capsule shell contains gelatin and the colourings Titanium Dioxide (E171), Indigocarmine (E132), Quinoline yellow (E104) and Iron oxide (E172). The ink contains shellac, Iron oxide E172, propylene glycol and potassium hydroxide.
What your medicine looks like
Doxycycline capsules are opaque pale green caps and opaque white bodies with “50mg” printed in black ink.
These capsules are available in a pack size of 28 capsules.
Marketing Authorisation Holder
Your capsules are made by
Company responsible for release of this medicine
This leaflet was last revised in May 2019.
Joshna House, Crowbridge Road, Orbital Park, Ashford, Kent, TN24 0GR
0845 437 5567
0845 437 5565
+44 (0)1233 506 574
0800 220 280