Atropine Sulfate Injection 600mcg in 1 ml (ampoules)

• Keep this leaflet. You may need to read it again
• If you have any further questions, please ask your doctor or nurse
• If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Atropine Solution for injection is and what it is used for
2. What you need to know before you are given Atropine Solution for injection
3. How Atropine Solution for injection is given
4. Possible side effects
5. How to store Atropine Solution for injection
6. Contents of the pack and other information

• you are allergic to Atropine sulfate or to any of the other ingredients of this medicine (listed in section 6).
• you suffer from closed-angle glaucoma (a condition that affects your eyes).
• you are a man with an enlarged prostate.
• you suffer from myasthenia gravis (weakness of breathing muscles).
• you suffer from pyloric stenosis (a narrowing of the opening that takes away food from your stomach).
• you suffer from paralytic ileus (your intestine stops functioning properly).
• you suffer from ulcerative colitis – a disease of the colon and rectum.

Talk to your doctor, pharmacist or nurse before being given Atropine Solution for injection if:

• you have urinary difficulties
• you have heart failure
• you have had a heart attack
• you have had a heart transplant
• you have chronic obstructive pulmonary disease (a condition where the airflow to your lungs is restricted and you may cough and feel breathless)
• you have an overactive thyroid
• you have high blood pressure
• you have a fever
• you have diarrhoea
• you have reflux oesophagitis (heartburn)

Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines including medicines obtained without prescription.

Other medicines which may interact with Atropine Solution for injection are:

• medicines to treat psychosis or depression.
• amantadine (a medicine for Parkinson’s disease)
• antihistamines (medicines used to treat hayfever and allergies)
• medicines to regulate your heart (disopyramide and mexiletine)
• ketoconazole (a medicine to treat fungal infections).
• medicines that you take by allowing them to dissolve slowly in your mouth – atropine may cause your mouth to become dry, making it more difficult for these medicines to dissolve.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before you are given this medicine.

You should not drive or use machinery if you are affected by the administration of Atropine Solution for injection.

Since the injection will be given to you by a doctor or nurse, it is unlikely that you will be given too much. If you think you have been given too much, or you begin to feel your heart beating very fast, you are breathing quickly, have a high temperature, feel restless, confused, have hallucinations, or lose co-ordination you must tell the person giving you the injection immediately.

• Sudden life – threatening allergic reaction such as rash, itching or hives on the skin, swelling of the face, lips, tongue or other parts of the body, shortness of breath, wheezing or trouble breathing.

Other Side effects include:

• drowsiness
• blurred vision
• dry mouth with difficulty swallowing
• thirst
• dilation of the pupils
• flushing
• dryness of the skin
• slow heart beat followed by fast heart beat
• palpitations (you are aware of your heart beating)
• difficulty in passing urine or constipation
• vomiting
• confusion especially in the elderly or severe confusion
• coughing and bringing up phlegm ( bronchial plugs)
• restlessness
• hallucinations
• changes in the way the heart beats (arrhythmias)
• heart condition ( atrioventricular block) after heart transplantation
• fever

If you get any side effects, talk to your doctor, pharmacist or nurse: This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme - website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine.

The active ingredient is Atropine Sulfate 0.06% w/v.

The other ingredients are sodium chloride and water for injections. It may also include sodium hydroxide and sulfuric acid.

Atropine Solution for injection is a clear, colourless solution supplied in 1ml, (Type I) clear glass ampoules. The ampoules are supplied to your pharmacist or doctor in packs of 10.