- heparin sodium
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet. The original leaflet can be viewed using the link above.
The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on 0800 198 5000. The product code(s) for this leaflet is: PL20417/0109 .
Heparin sodium 1000 IU/ml ampoule, solution for infusion
PACKAGE LEAFLET: INFORMATION FOR THE USER
Heparin sodium 1,000 IU/ml ampoule, solution for infusion
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
What is in this leaflet
1. What Heparin infusion is and what it is used for
2. What you need to know before you use Heparin infusion
3. How to use Heparin infusion
4. Possible side effects
5. How to store Heparin infusion
6. Contents of the pack and other information
1. WHAT HEPARIN INFUSION IS AND WHAT IT IS USED FOR
Heparin infusion belongs to a group of medicines called anticoagulants.
Heparin changes the way your blood clots. This means your blood keeps flowing smoothly inside your blood vessels. These are the tubes that carry blood around your body and are called arteries and veins.
Heparin infusion is used:
An example is a harmful blood clot in a vein deep inside your body. This is usually in your leg (deep vein thrombosis or DVT for short). Another example is a clot which blocks the blood supply to your lungs (pulmonary embolism).
It is more likely these clots will form if you are either overweight, pregnant, have certain blood disorders or have already had a pulmonary embolism, DVT, heart attack or stroke. It can also happen if you do not move around for long periods of time. This could be because you have had surgery or you have another illness.
2. WHAT YOU NEED TO KNOW BEFORE YOU USE HEPARIN INFUSION
Do not use Heparin Infusion:
Important: If you are having an epidural or spinal anaesthetic
You must remind your doctor that you are having Heparin infusion before you receive any anaesthetic.
If you are pregnant please also read the section of this leaflet “Pregnancy, breast-feeding and fertility”.
After you have the anaesthetic your doctor or nurse will make regular checks. This is to check if you are getting any major bleeding or bruising around your spine. This may cause paralysis that could be permanent. Any signs this may be happening to you include tingling, weakness or numbness in your lower legs or body, back pain or problems in going to the toilet. This happens very rarely.
After you have the anaesthetic your doctor will tell you when you can take your medicine again.
Take special care with Heparin infusion
Before you have Heparin infusion, tell your doctor:
Your doctor may take a blood test before you start having this medicine, and while you are having it. This is so the doctor can check you are having the right dose. This is also to check the level of the clotting cells (platelets) and potassium in your blood.
This medicine may make you bleed more easily. The doctor or nurse should take care when giving you any other injections or procedures. This medicine must not be injected into your muscles.
Your doctor will take particular care if:
Other medicines and Heparin
Please tell your doctor or pharmacist if you are taking, or have recently taken any other medicines. This includes any medicines which you have bought without a prescription.
You must tell your doctor or pharmacist if you are taking any of the following medicines:
Your doctor may carry out check-ups on you, including blood tests, if you take any of these medicines at the same time as Heparin infusion.
Tobacco smoke can also interfere with the working of heparin. You should inform your doctor if you smoke.
The presence of Heparin in the blood can affect the results of some blood tests such as thyroid tests and the levels of calcium or some antibiotics (e.g. gentamicin) in the blood.
Pregnancy, breast-feeding and fertility
If you are pregnant or might be pregnant, tell your doctor before you are given Heparin infusion.
If you become pregnant while having this medicine, tell your doctor.
If you are being given heparin injection bleeding may be a problem during pregnancy or after delivery. Your bones may get thinner if you receive heparin for a long time during pregnancy.
If you are pregnant and are going to have an epidural anaesthetic, you should stop having your medicine. Ask your doctor for advice.
If you are breast-feeding, ask your doctor for advice before having Heparin infusion.
Driving and using machines
Usually your medicine may have little effect on your ability to drive or use machines. However, you should check with your doctor if you feel any side effect that may stop you from driving or using machines.
Important information about some of the ingredients of Heparin infusion
This medicine contains:
Please ask your doctor if you are worried about any of the ingredients in this medicine.
3. HOW TO USE HEPARIN INFUSION
Heparin infusion will be given to you by a doctor or a nurse.
Heparin infusion should not be mixed with any other injection.
It may be given under your skin or into your vein.
Treatment of thrombo-embolic disorders:
500 IU/kg bodyweight daily or 5,000 - 10,000 IU every 4 hours as a continuous infusion in sodium chloride injection or dextrose injection. The dose should be individually adjusted according to coagulation tests.
Lower doses may be used in the elderly
Treatment of clotting during haemodialysis:
Initially: 1,000 - 5,000 IU.
1,000 - 2,000 IU per hour, adjusted to maintain clotting time greater than 40 minutes.
The recommended dose of Heparin Infusion
Your doctor will prescribe the right dose for you.
If you take more Heparin Infusion than you should:
Your doctor or nurse will give you this medicine. If you think you may have been given too much, tell your doctor or nurse straight away.
You may start to haemorrhage (bleed severely). Please read section 4 so you can spot any signs this may be happening to you.
You may be given another injection of a medicine called protamine sulphate.
If you have missed a dose of Heparin infusion
Your doctor or nurse will give you this medicine. If you think that you have missed a dose then tell your doctor or nurse.
If you have any further questions about taking this medicine, please ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Heparin infusion can cause side effects, although not everybody gets them.
Important side effects to look out for
You must get urgent medical help if you have any of the following symptoms. You may be having an allergic reaction:
You must get urgent medical help if you have any of the following symptoms after having an epidural or spinal anaesthetic. You may be developing paralysis:
You should tell your doctor straight away if you spot any of the following signs which mean you may be starting to bleed severely:
Other possible side effects
Common side effects (probably affect up to 1 in 10 people)
Uncommon side effects (probably affect less than 1 in 100 people)
Rare side effects (probably affect less than 1 in 1,000 people)
Very rare side effects (probably affect less than 1 in 10,000 people)
If any of the side effects become serious, or if you notice any side effects not listed in this leaflet, tell your doctor or pharmacist.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed on this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine.
5. HOW TO STORE HEPARIN INFUSION
Medicines should not be thrown away in waste water or in household waste. Please ask your pharmacist how to throw away any medicine you do not need anymore. If you do this you will help protect the environment.
6. CONTENTS OF THE PACK AND OTHER INFORMATION
What Heparin Infusion contains:
You can find important information about some of the ingredients near the end of section 2, just before section 3.
What Heparin Infusion looks like and contents of the pack:
Heparin infusion is a clear, colourless or pale yellow liquid.
This medicine comes in glass ampoules containing 5, 10 or 20 ml.
There are 10 ampoules in a carton.
Marketing Authorisation Holder:
This leaflet was last revised in June 2018.