Dulcolax Twelve Plus 10 mg Suppositories

• Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist have told you.
• Keep this leaflet. You may need to read it again.
• Ask your pharmacist if you need more information or advice.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Dulcolax Twelve Plus Suppositories are and what they are used for
2. What you need to know before you use Dulcolax Twelve Plus Suppositories
3. How to use Dulcolax Twelve Plus Suppositories
4. Possible side effects
5. How to store Dulcolax Twelve Plus Suppositories
6. Contents of the pack and other information

• You are allergic (hypersensitive) to bisacodyl or hard fat
• You have severe dehydration
• You have a bowel condition called “ileus” (blockage in the intestine)
• You have a serious abdominal condition such as appendicitis
• You have severe abdominal pain with nausea and vomiting
• You have a blocked bowel (intestinal obstruction)
• You have inflammation of the bowel (small or large intestine)
• You have cracking of the skin around your back passage (anal fissures)
• You have inflammation or ulcers around your back passage (ulcerative proctitis)

Do not take this medicine if any of the above applies to you. Do not use in children under the age of 12 years. If you are not sure, talk to your pharmacist or doctor before using this medicine.

Does this help with weight loss?

Stimulant laxatives (including Dulcolax Twelve Plus Suppositories) do not help with weight loss. They do not reduce the absorption of calories or nutrients.

They can cause watery stools (diarrhoea), abdominal cramps and dehydration. Dehydration can seem like weight loss.

Overuse of laxatives may damage your health by:

• Causing disturbances of electrolyte and mineral balances. Sodium, potassium, magnesium, and phosphorus are electrolytes and minerals that are present in very specific amounts necessary for proper functioning of the nerves and muscles, including those of the colon and heart. Upsetting this delicate balance can cause incorrect functioning of these vital organs.
• Severe dehydration may cause tremors, weakness, blurry vision, fainting, kidney damage, and, in extreme cases, death. Dehydration often requires medical treatment.
• Overuse of laxatives must be avoided as it may harm the intestinal function

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is because Dulcolax Twelve Plus Suppositories can affect the way some other medicines work. Also, some other medicines can affect the way Dulcolax Twelve Plus Suppositories work.

In particular, tell your doctor or pharmacist if you are taking:

• Water tablets (diuretics) such as bendrofluazide or furosemide (frusemide)
• Steroid medicines such as prednisolone.
• Other laxative medicines.

If you are not sure if any of the above applies to you, talk to your pharmacist or doctor before using Dulcolax Twelve Plus Suppositories.

Talk to you pharmacist or doctor before using Dulcolax Twelve Plus Suppositories if you are pregnant, planning to become pregnant or are breast-feeding.

Some people may feel dizzy or faint while taking this medicine. If this happens to you, wait until these feelings go away before driving or using machines.

The suppositories should only be used in your back passage.

1. Take off the foil wrapping
2. Lie on one side and pull your knees up towards your chest. Keep one leg drawn up more than the other
3. Use your first finger (index finger) or middle finger to push in the suppository
4. Gently push the suppository as far as possible into your back passage, pointed end first
5. Once it is as far as it will go, push it side-ways to make sure it touches the wall of the bowel
6. Lower your legs to a comfortable position whilst the suppository is retained in place
7. Keep the suppository inside you for at least 30 minutes

• You may not have put it in high enough. Push it in as far as possible
• Try to keep it in for 30 minutes, even if you feel like you urgently need to go to the toilet. This is how long it takes to work

Adults and children 12 years and over:

Put one 10 mg suppository into the back passage for immediate effect (they usually have a laxative effect within 10 to 30 minutes). Only use one suppository per day. This should not be used in children or adolescents under the age of 12 years.

Length of treatment

These suppositories should not be used every day for more than 5 days. If you need laxatives every day, then you should see your doctor to find the cause of your constipation. Overuse can be harmful.

It may be harmful to:

• Use too many Dulcolax Twelve Plus Suppositories
• Use Dulcolax Twelve Plus Suppositories for too long
  This is because using too much for too long may lead to:
  • Imbalance of fluid and salts in the body. This can affect the tightness of muscles such as those in the bowel. It can also affect the salts in the blood.
  • Low levels of potassium in the blood (called ‘hypokalaemia’). This can make you tired, dizzy, make your muscles weak and cause an uneven heartbeat.
  • Dehydration, making you thirsty, feel faint and giving you headaches. It can also mean you cannot pass enough urine.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in Google Play or Apple App Store By reporting side effects you can help provide more information on the safety of this medicine.

• Dulcolax Twelve Plus 10 mg Suppositories contain 10 mg of the active ingredient bisacodyl
• The suppositories are made from hard fat, which is an ingredient needed to mould the suppository into the correct shape

Dulcolax Twelve Plus 10 mg Suppositories are packed in cartons containing blister strips. The cartons contain 10 or 12 suppositories. Not all pack sizes may be marketed.

Dulcolax Twelve Plus Suppositories are manufactured by: