Clonidine Hydrochloride 100 microgram Tablets

Patient Leaflet Updated 08-Jun-2026 | Flamingo Pharma (UK) Ltd

Clonidine Hydrochloride 100 microgram Tablets

PACKAGE LEAFLET: INFORMATION FOR THE USER

Clonidine Hydrochloride 100 microgram Tablets

Clonidine Hydrochloride

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you
  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
  • Clonidine hydrochloride 100 microgram Tablets are referred as Clonidine 100 microgram Tablets in this leaflet.

What is in this leaflet

1. What Clonidine 100 microgram Tablets are and what they are used for
2. What you need to know before you take Clonidine 100 microgram Tablets
3. How to take Clonidine 100 microgram Tablets
4. Possible side effects
5. How to store Clonidine 100 microgram Tablets
6. Contents of the pack and other information

1. What Clonidine 100 microgram Tablets are and what they are used for

Clonidine 100 microgram Tablets contain a medicine called clonidine. This belongs to a group of medicines called anti-hypertensives. Clonidine 100 microgram Tablets are used to lower high blood pressure (to treat hypertension).

2. What you need to know before you take Clonidine 100 microgram Tablets
Do not take Clonidine 100 microgram Tablets if:
  • You are pregnant, likely to get pregnant or are breast-feeding
  • You are allergic (hypersensitive) to clonidine or any of the other ingredients of Clonidine Hydrochloride Tablets (see section 6: Further information)
  • You have a slow heart rate due to heart problems

Do not take this medicine if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before using Clonidine Hydrochloride Tablets.

Take special care with Clonidine 100 microgram Tablets

Check with your doctor or pharmacist before taking Clonidine 100 microgram Tablets if:

  • You have Raynaud's disease (a problem with circulation to the fingers and toes) or other blood circulation problems, including circulation to the brain
  • You have heart or kidney problems
  • You have or have ever had depression
  • You have constipation
  • You have a nerve disorder that causes your hands and feet to feel different ('altered sensation') or low blood pressure when you stand up.

If you are not sure if any of the above apply to you, t talk to your doctor or pharmacist before taking Clonidine 100 microgram Tablets.

As you may get dry eyes whilst taking this medicine, this may be a problem if you wear contact lenses.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines that you buy without a prescription and herbal medicines. This is because Clonidine Hydrochloride Tablets can affect the way some other medicines work. Also some other medicines can affect the way Clonidine 100 microgram Tablets work.

In particular, tell your doctor or pharmacist if you are taking any of the following medicines:

  • Other medicines that make you drowsy
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) such as ibuprofen
  • Medicines for depression such as imipramine or mirtazapine
  • Medicines for severe mental illness such as schizophrenia. These are also known as 'antipsychotics' and include chlorpromazine

Please also tell your doctor or pharmacist if you are taking any of the following medicines for high blood pressure or other heart problems:

  • Beta blockers such as atenolol
  • Water tablets ('diuretics') such as furosemide
  • Alpha blockers such as prazosin or doxazosin. These can also be used for prostate problems in men
  • Vasodilators such as diazoxide or sodium nitroprusside
  • Calcium antagonists such as verapamil or diltiazem hydrochloride
  • ACE inhibitors such as captopril or lisinopril
  • Digitalis glycosides such as digoxin

If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Clonidine 100 microgram Tablets.

Tests

If you are having any blood tests, tell the person giving the test that you are taking this medicine. This is because Clonidine 100 microgram Tablets can affect results relating to your liver.

Operations

If you are going to have an operation, keep taking your Clonidine 100 microgram Tablets. If you need to go into hospital, take the tablets with you.

Taking Clonidine 100 microgram Tablets with food and drink

You may feel drowsy while taking Clonidine Hydrochloride Tablets. Drinking alcohol while taking Clonidine 100 microgram Tablets can make this worse.

Pregnancy and breast-feeding

Do not take Clonidine 100 microgram Tablets if you are pregnant, likely to get pregnant or are breast-feeding.

Driving or using machines

You may feel drowsy, dizzy, or could have some disturbances of vision. If affected, you should not drive, operate machinery or take part in any activities where these may put you or others at risk.

Important information about some of the ingredients of Clonidine 100 microgram Tablets

Clonidine 100 microgram Tablets contain lactose (a type of sugar). If you have been told by your doctor that you cannot tolerate or digest some sugars, talk to your doctor before taking this medicine.

This medicine contains less than 1 mmol sodium (23 mg) per tablets, that is to say essentially 'sodium-free'.

3. How to take Clonidine 100 microgram Tablets

Always take Clonidine 100 microgram Tablets exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

Your doctor will start you on a low dose and gradually increase it. This will depend on how well your medicine works to control your blood pressure.

Taking this medicine
  • Take this medicine by mouth
  • The usual starting dose is between 50 microgram and 100 microgram, three times a day
  • If necessary, your doctor will gradually increase the dose
  • Most people's blood pressure is controlled by taking between 300 microgram and 1200 microgram

Clonidine 100 microgram Tablets are not recommended for children.

If you take more Clonidine 100 microgram Tablets than you should

If you take more Clonidine 100 microgram Tablets than you should, talk to a doctor or go to a hospital straight away. Take the medicine pack with you, even if there are no tablets left.

If you forget to take 100 microgram Tablets

If you forget a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

If you stop taking Clonidine 100 microgram Tablets

Do not stop taking Clonidine 100 microgram Tablets without first talking to your doctor. If you have been using this medicine for a long time, you may feel agitated when you stop taking it. This is called a 'withdrawal effect'.

If you have any further questions on the use of Clonidine 100 microgram Tablets, ask your doctor or pharmacist.

4. Possible Side Effects

Like all medicines, Clonidine 100 microgram Tablets can cause side effects, although not everybody gets them.

The side effects described below have been experienced by people taking Clonidine Hydrochloride Tablets. They are listed as either very common, common, uncommon, rare or not known.

Very common (affects more than 1 in 10 people)

  • Dizziness, feeling tired and more relaxed than usual (sedation)
  • Feeling dizzy when you stand up (because your blood pressure has fallen sharply) Dry mouth

Common (affects less than in 1 in 10 people, more than 1 in 100 people)

  • Depression, sleeping problems
  • Headache
  • Constipation, feeling sick (nausea), pain below the ear (from the salivary gland), being sick (vomiting)
  • Erectile dysfunction
  • Fatigue

Uncommon (affects less than 1 in 100 people, more than 1 in 1,000 people)

  • Problems with understanding what is happening around you, hallucinations, nightmares
  • Your hands and feet feeling different ('altered sensation')
  • Regular unusually slow heart beat
  • Raynaud's phenomenon (a problem with circulation to the fingers and toes)
  • Itching, rash, urticaria (nettle rash)
  • A feeling of discomfort and fatigue ('malaise')

Rare (affects less than 1 in 1,000 people, more than 1 in 10,000 people)

  • Breast growth ('gynaecomastia') in men
  • Dry eyes
  • Irregular heartbeat
  • Drying out of the lining of the nose
  • Pseudo-obstruction of the large bowel, which causes colicky pain, vomiting and constipation. Contact your doctor straight away if you have all these side effects.
  • Hair loss
  • Increase in your blood sugar

Not known

  • Confusion, loss of libido
  • Blurred vision
  • Abnormally slow heart beat

Two cases of hepatitis (inflammation of the liver) have also been reported. This might show up in some blood tests. Your body may hold onto more water than usual (fluid retention).

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www. mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side affects you can help provide more information on the safety of this medicine.

5. How to store Clonidine 100 microgram Tablets

Keep out of sight and reach of children.

Do not store above 30°C. Keep the blisters in the outer carton.

Do not use Clonidine 100 microgram Tablets after the expiry date which is stated on the packaging. The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and other information

What Clonidine 100 microgram Tablets contains

  • The active substance is clonidine hydrochloride. Each tablet contains 100 micrograms of clonidine hydrochloride.
  • The other ingredients are: lactose monohydrate, microcrystalline cellulose, maize starch, sodium starch glycolate Type-A , magnesium stearate, pregelatinised maize starch and povidone.

What Clonidine 100 microgram Tablets looks like and contents of the pack

White to off white, round shaped, biconvex uncoated tablet debossed with "C" separated by break line "100" on one side and plain on other side. The tablets have diameter of 10.00 mm and thickness of 5.00 mm. The tablet can be divided into equal doses.

These medicines are available in Aluminium foil-PVC White Opaque film blister packs of 100's tablets.

Marketing Authorization Holder
Flamingo Pharma (UK) Ltd.
First Floor
Kirkland House
11-15 Peterborough Road
Harrow
Middlesex
HA1 2AX
United Kingdom

Manufacturer
Flamingo Pharma (UK) Ltd.
The Bloc
38 Springfield Way
Anlaby
Hull
HU 10 6RJ
United Kingdom

Clonidine Hydrochloride 100 microgram Tablets- PL 43461/0189

This leaflet was last revised in 04/2026.

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Company Contact Details
Flamingo Pharma (UK) Ltd
Address

The BLOC, 38 Springfield Way, Kingston Upon Hull, HU10 6RJ, UK

Medical Information Direct Line

+44 8000668348

Stock Availability
Telephone

+44 (0) 7784240228

WWW

http://www.flamingopharma.co.uk