Liothyronine 15 microgram Tablet

• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Liothyronine Sodium Tablets are and what they are used for
2. What you need to know before you take Liothyronine Sodium Tablets
3. How to take Liothyronine Sodium Tablets
4. Possible side effects
5. How to store Liothyronine Sodium Tablets
6. Contents of the pack and other information

• if you are allergic to liothyronine sodium or any of the other ingredients of this medicine (listed in section 6 at the end of this leaflet),
• if you have angina (chest pain when exercising) or conditions affecting your heart or circulation,
• if you are suffering from thyrotoxicosis (condition due to over activity of the thyroid gland).

Talk to your doctor or pharmacist before taking Liothyronine Sodium Tablets if:

• you are suffering from diabetes. Liothyronine Sodium Tablets may raise blood sugar levels,
• you are suffering from a condition called myxoedema (which can happen when you have a problem with your thyroid gland) which makes your skin look swollen and dry,
• you are elderly,
• you have suffered from low levels of thyroid hormone in your body for a long time, as this may affect how your adrenal glands work. You may be given additional medication (corticosteriods) if this is the case,
• you are suffering from any heart problems,
• you are having increased blood pressure,
• you suffer from increased heart rate, sleeplessness, loose watery stools (suggesting increased metabolism) on initiation of treatment. In this case dose reduction would be required,
• you are initiating treatment, as an ECG test done at that time would be valuable,
• if you are pregnant or breast-feeding. if you are about to undergo laboratory testing for monitoring your thyroid hormone levels, you must inform your doctor and/or the laboratory personnel that you are taking or have recently taken biotin (also known as vitamin H, vitamin B7 or vitamin B8). Biotin may affect results of your laboratory tests. Depending on the test, the results may be falsely high or falsely low due to biotin. Your doctor may ask you to stop taking biotin before performing laboratory tests. You should also be aware that other products that you may take, such as multivitamins or supplements for hair, skin, and nails could also contain biotin. This could affect the results of laboratory tests. Please inform your doctor and/or the laboratory personnel, if you are taking such products (see section Other medicines and Liothyronine Sodium Tablets).

For more information, talk to your doctor.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Liothyronine Sodium Tablets may affect or be affected by the following medicines:

• anticoagulants (e.g. warfarin) used to thin the blood and prevent blood clots,
• anticonvulsants (e.g. carbamazepine or phenytoin) used to prevent fits,
• insulin and other treatments for diabetes,
• medicines called cardiac glycosides (e.g. digoxin) used to treat heart conditions such as heart failure,
• tricyclic antidepressants (e.g. amitriptyline/imipramine) used to treat depression,
• colestyramine / colestipol which reduces the level of cholesterol (fats) in the blood,
• oral contraceptives ('The Pill'),
• amiodarone, used to treat irregular heart beats,
• barbiturates, used to induce sleep and decrease anxiety,
• primidone, used for seizures or fits.

If you are taking or have recently taken biotin, you must inform your doctor and/or the laboratory personnel when you are about to undergo laboratory testing for monitoring your thyroid hormone levels. Biotin may affect results of your laboratory tests (see section Warnings and precautions).

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

The decision on whether it is best to take Liothyronine Sodium Tablets during pregnancy or breast-feeding will be made by your doctor.

This medicine should not interfere with your ability to drive or use machinery.

This medicine contains lactose, which is a sugar. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially 'sodium-free'.

The dose will depend upon your condition, ranging from 10 micrograms to 60 micrograms daily in divided doses.

Children below 12 years of age:

The dose may be started at 5 micrograms a day.

Adolescents (Children 12-17 years of age):

Initially 10-20 micrograms daily; increased to 60 micrograms daily in 2-3 divided doses.

The dose may be started at 5 micrograms a day.

Please note that your doctor will monitor your thyroid function regularly to make sure that you are given the right dose for your condition.

Contact your doctor or nearest hospital casualty department as soon as possible. Take any remaining tablets and this leaflet with you so the medical staff will know what you have taken. This may cause agitation, confusion, headache, sweating and a rapid pulse.

Do not take a double dose to make up for a forgotten tablet or dose. Take the next dose at the correct time and then go on as before. It is important, in order for your medicine to work, that doses are not forgotten.

Do not stop taking Liothyronine Sodium Tablets unless your doctor tells you to.

• Temporary loss of hair in children

These effects normally mean the dose of the medicine needs changing. You should consult your doctor, if these effects occur. The effects usually go away when the dose has been changed.

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

• The active substance is liothyronine sodium. Each tablet contains either 5 micrograms or 10 micrograms or 15 micrograms or 20 micrograms or 25 micrograms liothyronine sodium.
• The other excipients are: lactose monohydrate, partially pregelatinized maize starch, spray dried acacia, sodium chloride and magnesium stearate.

Liothyronine Sodium 5 microgram Tablets: white to off white, circular biconvex tablets, plain on one side and debossed with "L1" on the other side, 5.5 mm diameter.

Liothyronine Sodium 10 microgram Tablets: white to off white, circular biconvex tablets, plain on one side and debossed with "L2" on the other side, 5.5 mm diameter.

Liothyronine Sodium 15 microgram Tablets: White to off white, circular biconvex, uncoated tablets, debossed with "L4" on one side and plain on other side, 5.5 mm diameter.

Liothyronine Sodium 20 microgram Tablets: white to off white, circular biconvex tablets, plain on one side and debossed with "T3" on the other side, 5.5 mm diameter.

Liothyronine Sodium 25 microgram Tablets: White to off white, circular biconvex, uncoated tablets, debossed with "L5" on one side and plain on other side, 5.5 mm diameter.

Liothyronine Sodium 5, 10, 15, 20 and 25 microgram Tablets are available in blister packs of 7, 10, 14, 20, 28, 30, 56, 60, 84, 90 and 112 tablets.

Not all pack sizes may be marketed.