Zevona XL 30mg prolonged release tablets

• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Zevona XL tablets are and what are they used for
2. What you need to know before you take Zevona XL tablets
3. How to take Zevona XL tablets
4. Possible side effects
5. How to store Zevona XL tablets
6. Contents of the pack and other information

• if you are allergic to isosorbide mononitrate or any of the other ingredients of this medicine (listed in section 6)
• if you have ever had a stroke
• if you have very low blood pressure
• if you have severe anaemia
• if you have a heart problem called "cardiomyopathy" or "pericarditis" or you have narrow heart valves
• if you are taking sildenafil or similar medicines called Phosphodiesterase Type 5 Inhibitors (used for male impotence). See section "Other medicines and Zevona XL tablets".

Do not take Zevona XL tablets if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Zevona XL tablets.

Talk to your doctor or pharmacist before taking Zevona XL tablets if:

• You have ever had any serious damage to your heart, such as a heart attack or operation.

If any of the above apply to you, or you are not sure, talk to your doctor or pharmacist before taking Zevona XL tablets.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes medicines that you buy without a prescription and herbal medicines. This is because Zevona XL tablets can affect the way some medicines work and some medicines can have an effect on Zevona XL tablets.

Do not take Zevona XL tablets if you are taking the following medicines:

• Sildenafil or similar medicines called Phosphodiesterase Type 5 Inhibitors, (used for male impotence).

Do not take Zevona XL tablets if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Zevona XL tablets.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

You may feel dizzy after taking Zevona XL tablets. If this happens, do not drive or use any tools or machines.

Zevona XL tablets contain a type of sugar called lactose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

• Swallow the tablets whole
• Take the tablets with half a glass of water
• Do not crush or chew the tablets

• The recommended dose is 60 mg (two tablets) or 120mg (4 tablets) a day
• Take the medicine in the morning
• Your doctor may ask you to start on a low dose so that you are less likley to have a reaction to starting Zevona XL tablets.

You must not take Zevona XL tablets for a sudden attack of angina. If you have a sudden attack, take a glyceryl trinitrate tablet (follow the instructions given on the label).

Very occasionally, some users may see the remnants of the tablet in their bowel motions. This is quite normal and does not mean that the medicine has not been released.

Do not give these tablets to children.

If you take more Zevona XL tablets than you should, talk to a doctor or go to a hospital straight away. Take the medicine pack with you to the tablets can be identified.

• If you forget a dose take it as soon as you remember it. However if it is nearly time for the next dose, skip the missed dose.
• Do not take a double dose to make up for a forgotten dose.

Common (may affect up to 1 in 10 people)

• low blood pressure. This may make you feel faint or dizzy
• faster heartbeat
• headache
• feeling dizzy
• feeling sick (nausea)

Uncommon (may affect up to 1 in 100 people)

• being sick (vomiting)
• diarrhoea

Rare (may affect up to 1 in 1,000 people)

• fainting
• rash
• itchy skin

Very rare (may affect up to 1 in 10,000 people)

• pain in muscles

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov. uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects, you can help provide more information on the safety of this medicine.

• The active substance is isosorbide mononitrate. Each tablet contains 30 mg of isosorbide mononitrate.
• The other ingredients are: hypromellose, lactose monohydrate, pregelatinised starch, magnesium stearate, silica colloidal anhydrous.

Zevona XL tablets are white to off-white, oval prolonged-release tablets.

Zevona XL tablets are packaged blister packs containing 28 tablets.

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