Boots IBS Symptom Relief 135mg Tablets

Patient Leaflet Updated 15-Oct-2025 | THE BOOTS COMPANY PLC

Boots IBS Symptom Relief 135mg Tablets

PACKAGE LEAFLET: INFORMATION FOR THE USER

Boots IBS Symptom Relief 135 mg Tablets

(Mebeverine Hydrochloride)

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.

  • Keep this leaflet. You may need to read it again.
  • Ask your pharmacist if you need more information or advice.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
  • You must talk to a doctor if you do not feel better or if you feel worse after 14 days.

What is in this leaflet

1. What Boots IBS Symptom Relief Tablets are and what they are used for
2. What you need to know before you take this medicine
3. How to take this medicine
4. Possible side effects
5. How to store this medicine
6. Contents of the pack and other information

1. What Boots IBS Symptom Relief Tablets are and what they are used for

Boots IBS Symptom Relief Tablets contain the active ingredient mebeverine hydrochloride. This belongs to a group of medicines called antispasmodics.

This medicine is used to treat symptoms of irritable bowel syndrome (IBS). This is a very common condition which causes spasm and pain in the gut or intestine.

The intestine is a long muscular tube which food passes down so it can be digested. If the intestine goes into spasm and squeezes too tightly, you get pain. The way this medicine works is by relieving the spasm and pain.

The main symptoms of irritable bowel syndrome (IBS) include:

  • stomach pain and spasm
  • feeling bloated and having wind
  • having diarrhoea (with or without constipation)
  • small, hard, pellet-like or ribbon-like stools (faeces).

These symptoms may vary from person to person.

Talk to your doctor if you develop new symptoms or if these symptoms continue for more than 14 days.

Your diet and lifestyle can also help treat IBS

How you restrict your diet depends on the way IBS affects you. If you find that certain things bring on the symptoms, then it makes sense not to eat them. A high fibre diet may help, but ask your pharmacist for more information.

Some people find that learning to relax can help to lessen their symptoms of IBS. You may find it helpful to set aside a few moments each day to relax and gently unwind.

2. What you need to know before you take this medicine
Do not take this medicine if you:
  • are allergic to mebeverine hydrochloride or any of the other ingredients of this medicine (listed in section 6)
  • are younger than 18 years of age.

If any of the above applies to you, do not take this medicine and talk to your doctor or pharmacist

Warnings and precautions

See your doctor before using any IBS treatment if you:

  • have not suffered from IBS before
  • have developed new symptoms or your symptoms have become worse
  • have liver or kidney problems.

Talk to your pharmacist or doctor if any of the following applies to you:

  • you are 40 years of age or over and your symptoms have changed or it has been some time since you last had IBS
  • you have blood in your stools (faeces)
  • you are feeling sick (nauseous) or are sick (vomiting)
  • you are looking pale and feeling tired
  • you have constipation
  • you have a fever
  • you have recently travelled abroad
  • you are pregnant, or planning to become pregnant
  • you are a woman and you have unusual bleeding or discharge from your vagina
  • you have difficulty or pain when passing water (urinating).

Your doctor will tell you whether it is safe for you to start taking this medicine.

Boots IBS Symptom Relief Tablets with food and drink

You can drink alcohol while you are taking this medicine.

Other medicines and Boots IBS Symptom Relief Tablets

Mebeverine is not known to interact with other medicines but you should tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Pregnancy, breast-feeding and fertility

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. There is only limited information about the safety of this medicine for pregnant women. Your doctor may advise you to stop taking this medicine before you become pregnant or as soon as you know you are pregnant. This medicine should not be used during breast-feeding.

Driving and using machines

This medicine is not likely to affect you being able to drive or use any tools or machines.

Boots IBS Symptom Relief Tablets contain lactose and sodium

Lactose - If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

Sodium - This medicine contains less than 1mmol sodium (23mg) per tablet that is to say essentially 'sodium-free'.

3. How to take this medicine

Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.

Try to take the tablet twenty minutes before a meal - some people find their symptoms to be strongest after they have eaten.

Swallow the tablet whole with a glass of water. Do not chew the tablet.

How much to take

Adults (including the elderly):

  • The recommended dose is one tablet three times a day.
  • Do not take more than three tablets per day.
  • The number of tablets you take may be lowered if your symptoms improve.

Children and adolescents: This medicine is not recommended for use in children and adolescents below 18 years of age.

If you take more Boots IBS Symptom Relief Tablets than you should

If you or someone else takes too many tablets (an overdose), talk to a doctor or go to a hospital straight away. Take the medicine pack with you.

If you forget to take Boots IBS Symptom Relief Tablets

If you miss a tablet, wait until the next dose is due. Do not try to make up for the dose you have missed. Do not double dose to make up for a forgotten dose.

If you stop taking Boots IBS Symptom Relief Tablets

You can lower the dose if your symptoms get better.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

If you notice the following, stop taking the tablets and go to your doctor immediately, or your nearest hospital:

  • difficulty in breathing, swelling of the face, neck, tongue or throat (severe allergic reactions).

These other effects are less serious. If they bother you talk to a pharmacist:
  • skin rash, red itchy skin.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

5. How to store this medicine

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the blister and carton after 'EXP'. The expiry date refers to the last day of that month.

Do not store above 25°C. Store in the original package.

Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

6. Contents of the pack and other information
What Boots IBS Symptom Relief Tablets contain

The active substance is mebeverine hydrochloride. Each film-coated tablet contains 135mg of mebeverine hydrochloride.

The other ingredients are:

Tablet core: lactose monohydrate, silicified microcrystalline cellulose, sodium starch glycolate (Type A), povidone, talc (E553b), and magnesium stearate.

Tablet coating: poly (vinyl alcohol) - part hydrolyzed (E1203), talc (E553b), titanium dioxide (E171), glycerol monocaprylocaprate (type I) , and sodium laurilsulfate.

What this medicine looks like and contents of the pack

Boots IBS Symptom Relief Tablets are white to off-white, round film-coated tablets, 10mm diameter, debossed with M135 on one side and plain on the other side.

The tablets are packaged in PVC/PVdC-Alu blister packs.

Pack sizes: 7, 10, 12, 14, 15, 18, 20, 21, 28, 30, 56, 60, 84, 90 and 100 tablets.

Not all pack sizes may be marketed.

Marketing Authorisation Holder
Morningside Healthcare Ltd.
Unit C
Harcourt Way
Leicester
LE19 1WP
UK

Manufacturer
Morningside Pharmaceuticals Ltd.
5 Pavilion Way
Loughborough
LE11 5GW
UK

Morningside Pharmaceuticals Ltd. & Aspire Pharma Ltd.
Second Floor
Boss Court
7 Barton Close
Grove Park
Leicester
LE19 1SJ
UK

Aspire Pharma Ltd.
Unit 4
Rotherbrook Court
Bedford Road
Petersfield
GU32 3QG
UK

Distributed by
The Boots Company PLC
Nottingham
NG2 3AA

This leaflet was last revised in March 2025

If you would like any further information about this medicine, please contact

The Boots Company PLC
Nottingham
NG2 3AA

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Product name: Boots IBS Symptom Relief 135 mg Tablets

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Company Contact Details
THE BOOTS COMPANY PLC
Address

1 Thane Road West, Beeston, Nottingham, NG2 3AA

Fax

+44 (0)1159 592 565

Telephone

+44 (0)1159 595 165