POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet, the original can be viewed in PDF format using the link above.
The text only version may be available from RNIB in large print, Braille or audio CD. For further information call RNIB Medicine Leaflet Line on 0800 198 5000. The product code(s) for this leaflet are: PL15142/0104, PL15142/0103.
Manerix 150mg and 300mg
Patient Information Leaflet
150 mg and 300 mg film-coated Tablets
Please read all of this leaflet carefully before you start taking this medicine.
In this leaflet:
1. What Manerix is and what it is used for
2. Before you take Manerix
3. How to take Manerix
4. Possible side effects
5. How to store Manerix
6. Further information
7. More information about your condition
1. WHAT MANERIX IS AND WHAT IT IS USED FOR
Manerix contains a medicine called moclobemide. This belongs to a group of medicines called antidepressants.
Manerix is used to treat depression and social phobia. For further information about these conditions, see Section 7.
Manerix works by increasing the levels of important chemical messengers in your brain. This increase can help your depression or social phobia.
2. BEFORE YOU TAKE MANERIX
Do not take Manerix if:
Do not take Manerix if any of the above applies to you. If you are not sure, talk to your doctor or pharmacist before taking Manerix.
Take special care with Manerix
Check with your doctor or pharmacist before taking Manerix if:
If any of the above apply to you, or if you are not sure, talk to your doctor or pharmacist before you take Manerix.
Thoughts of suicide and worsening of your depression or anxiety disorder
If you are depressed and/or have anxiety disorders you can sometimes have thoughts of harming or killing yourself. These may be increased when first starting antidepressants, since these medicines all take time to work, usually about two weeks but sometimes longer. You may be more likely to think like this if:
You may find it helpful to tell a relative or close friend that you are depressed or have an anxiety disorder, and ask them to read this leaflet. You might ask them to tell you if they think your depression or anxiety is getting worse, or if they are worried about changes in your behaviour.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines that you buy without a prescription and herbal medicines. This is because Manerix can affect the way some medicines work. Also some other medicines can affect the way Manerix works.
Do not take Manerix, and tell your doctor or pharmacist, if you are taking the following:
Tell your doctor or pharmacist if you are taking any of the following medicines:
Taking Manerix with food and drink
Do not eat large quantities of foods containing tyramine when you are taking Manerix. These include:
If you are not sure about this talk to your doctor or pharmacist before you take Manerix.
Pregnancy and breast-feeding
Do not take Manerix if you are pregnant, trying to get pregnant or are breastfeeding, unless your doctor has told you to.
Driving and using machines
Manerix is not likely to affect your ability to drive or use any tools or machines. Talk to your doctor if you notice any effects that might affect driving, or using tools or machines, particularly when you start taking Manerix.
Important information about some of the ingredients of Manerix
This medicine contains lactose, which is a type of sugar. If you have been told by your doctor that you cannot tolerate or digest some sugars (have an intolerance to some sugars), talk to your doctor before taking this medicine.
3. HOW TO TAKE MANERIX
Always take Manerix exactly as your doctor has told you. You should check with your doctor if you are not sure.
Manerix is not suitable for children or adolescents.
Take your tablets at the end of a meal. Swallow each tablet with a drink of water.
People with severe liver disease:
Your doctor will decide the right dose for you. This will usually be lower than the doses stated above.
If you take more Manerix than you should
If you take more Manerix than you should or someone else takes your medicine by mistake, talk to a doctor or go to a hospital straight away.
Take the medicine pack with you.
If you forget to take Manerix
If you stop taking Manerix
Even when you start to feel better, you should keep taking your tablets for as long as your doctor tells you to.
Do not stop taking this medicine without talking to your doctor first.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines Manerix can cause side effects, although not everyone will get them.
If you have an allergic reaction, stop taking Manerix and see a doctor straight away. The signs may include:
Other possible side effects:
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard
By reporting side effects you can help provide more information on the safety of this medicine.
5. HOW TO STORE MANERIX
6. FURTHER INFORMATION
What Manerix contains
The active substance in Manerix tablets is moclobemide. The tablets come in two different strengths:
Other ingredients in both tablets are: lactose, maize starch, povidone K30, sodium starch glycollate, magnesium stearate, hypromellose, ethylcellulose, polyethylene glycol 6000, talc and titanium dioxide (E171). The 150 mg tablets also contain yellow iron oxide (E172).
What Manerix looks like and contents of the pack
Manerix 150 mg tablets are oval and pale yellow in colour. They have a score line on one side and are marked 150 on the other.
Manerix 300 mg tablets are oval and white to off-white in colour. They have a score line on one side and are marked 300 on the other.
Manerix is supplied in blister packs containing either 28, 30, 60, 84 or 100 tablets. Not all pack sizes may be marketed.
The Marketing Authorisation holder is:
The manufacturer responsible for batch release is:
7. MORE INFORMATION ABOUT YOUR CONDITION
What is depression?
The signs of this problem (condition) can include extreme feelings of sadness, low mood, tearfulness, worry, changes in sleep pattern (such as difficulty sleeping) or difficulty enjoying life as you used to. If these feelings affect your everyday life or last for a long time it is important to get help from your doctor. Depression is a common medical problem affecting around one in four women and one in ten men at some time in their lives.
What is social phobia?
Social phobia is a common medical problem that can affect both men and women. The signs of this condition are an extreme fear of being seen doing something embarrassing or humiliating. This can cause problems even when taking part in simple social activities such as eating, drinking, speaking, meeting people and going to parties. People with this condition will be too afraid to take part in social occasions.
This leaflet was last revised in 11/2013.
Manerix is a registered trade mark.
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