- desmopressin acetate
POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet, the original can be viewed in PDF format using the link above.
The text only version may be available from RNIB in large print, Braille or audio CD. For further information call RNIB Medicine Leaflet Line on 0800 198 5000. The product code(s) for this leaflet are: PL 03194/0094, PL 03194/0095.
DesmoMelt 120mcg and 240 mcg oral lyophilisate
DesmoMelt* oral lyophilisate
desmopressin (as acetate)
Read all of this leaflet carefully before you start taking this medicine.
Your medicine is called DesmoMelt oral lyophilisate. The lyophilisates look like tablets, but are much softer and lighter. They are intended for sublingual use (to be placed under the tongue where they will dissolve completely). They are referred to as DesmoMelt or melt(s) in this leaflet.
Marketing Authorisation Holder:
1. What DesmoMelt is and what it is used for
This medicine is intended for sublingual use. It is available in two strengths: 120 or 240 micrograms of desmopressin (as acetate), an antidiuretic (reduces urine production).
This medicine is used to treat primary nocturnal enuresis (bedwetting) in children (from 5 years of age) and adults (up to 65 years of age).
2. Before you take DesmoMelt
Do not take this medicine:
Please consult your doctor before taking this medicine:
Before you commence treatment with this medicine, you should have received appropriate advice concerning fluid intake, from a doctor or nurse. Excessive fluid intake may lead to a build up of water in the body. While you are on treatment with this medicine:
If you are pregnant or planning a pregnancy, please inform your doctor before you take this medicine, as blood pressure monitoring is recommended due to the increased risk of pre-eclampsia. Symptoms of pre-eclampsia include high blood pressure, oedema (swelling due to the build up of fluid) and proteinuria (protein in the urine).
If you are breast-feeding ask your doctor or pharmacist for advice before taking this medicine.
Taking/using other medicines:
Please inform your doctor or pharmacist if you are taking or have recently taken or used any other medicines - even those not prescribed.
3. How to take DesmoMelt
It is important that you do not take more than the prescribed dose in any 24 hour period.
If you have the impression that the effect of this medicine is too strong or too weak, talk to your doctor or pharmacist.
Bedwetting from the age 5 years:
The usual starting dose is one DesmoMelt 120 micrograms sublingually (under the tongue) at bedtime. Depending on how well the bedwetting is controlled, your doctor may increase the dose to either two DesmoMelts 120 micrograms or one DesmoMelt 240 micrograms sublingually (under the tongue) at bedtime. The need for continued treatment is normally checked every three months.
If you take more of this medicine than you should:
If you take more of this medicine than you should, talk to your doctor or pharmacist immediately.
If you forget to take this medicine:
Do not take double doses to make up for forgotten doses. Take the next dose at the usual time.
4. Possible side effects
Most people taking this medicine find it causes them no problems. However, like all medicines, this medicine can have side effects. Excessive fluid intake may lead to a build up of water which dilutes the salt in the body in severe cases. This can become a serious problem and may lead to convulsions. Early symptoms may include an unusually bad or prolonged headache, confusion, unexplained weight gain, nausea or vomiting. If you experience one or more of these symptoms, stop taking this medicine. Tell your doctor immediately or go to your nearest casualty department.
Side effects include headache, stomach pain and nausea. Isolated cases of allergic skin reactions and more severe general allergic reactions have been reported. Very rare cases of emotional disorders including aggression in children have been reported.
If you experience one or more of these side effects or any other undesirable effects, please inform your doctor or pharmacist.
5. Storing DesmoMelt
Keep this medicine out of the reach and sight of children.
Store in the original package.
Do not take this medicine after the expiry date on the packaging.
If you are unsure about the storage, ask your pharmacist. It is best to return all old and unused medicines to your pharmacist for safe disposal.
DesmoMelt 120 micrograms oral lyophilisate PL 03194/0094
DesmoMelt 240 micrograms oral lyophilisate PL 03194/0095
This leaflet was revised in May 2008.
*DesmoMelt is a trademark of Ferring BV.