POM: Prescription only medicine
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Below is a text only representation of the Patient Information Leaflet, the original can be viewed in PDF format using the link above.
The text only version may be available from RNIB in large print, Braille or audio CD. For further information call RNIB Medicine Leaflet Line on 0800 198 5000. The product code(s) for this leaflet is: PL 15142/0002.
Ancotil 2.5g/250ml Solution for Infusion
Patient Information Leaflet
Ancotil® 2.5 g/250ml
(1g in 100 ml)
Solution for Infusion
Read all of this leaflet carefully before you start using this medicine.
In this leaflet:
1. What Ancotil is and what it is used for
2. Before you are given Ancotil
3. How Ancotil is given
4. Possible side effects
5. How Ancotil is stored
6. Further information
1. WHAT ANCOTIL IS AND WHAT IT IS USED FOR
Ancotil Solution for Infusion contains an anti-fungal agent. It is used to treat certain yeast and fungal infections.
2. BEFORE YOU ARE GIVEN ANCOTIL SOLUTION FOR INFUSION
You should not be given Ancotil
Take special care with Ancotil
Tell your doctor before you start treatment
Using other medicines
Females of childbearing potential under treatment must use effective contraceptive during treatment and for one month after treatment. Male patients (or their female partners of childbearing potential) must use effective contraception during treatment and for three months after treatment (See Pregnancy and breastfeeding section).
Tell your doctor before you start treatment if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. In particular, tell your doctor if you are taking the medicine cytarabine (which is used to treat certain leukaemias), medicines to treat chickenpox or shingles (brivudine, sorivudine) or have used them in the last 4 weeks.
These medicines may increase the possibility of unwanted effects with Ancotil. If you are taking medicines for epilepsy containing phenytoin, your doctor may do some blood tests.
Pregnancy and breast-feeding
You must tell your doctor before you start treatment if you are pregnant, if you think you may get pregnant or if you are breast-feeding.
Contraception in males and females
Females of childbearing potential under treatment must use effective contraceptive during treatment and for one month after treatment. Male patients (or their female partners of childbearing potential) must use effective contraception during treatment and for three months after treatment.
3. HOW ANCOTIL IS GIVEN
Ancotil is administered only in a hospital and is administered by a doctor or nurse. It is usually given into a vein or by a procedure called “intraperitoneal infusion” while you are in hospital.
The usual total daily dose is 100 to 150 mg/kg bodyweight in divided doses.
In some instances, you may be given up to a total daily dose of 200 mg/kg bodyweight in divided doses.
Smaller doses may be given to patients with kidney problems.
The treatment period with Ancotil will vary on a patient by patient basis, but treatment will not usually be longer than a week.
Ancotil can be given with a glucose and/or saline infusion. It should not be mixed in the same solution with other medicines.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Ancotil can cause side effects, although not everybody gets them.
Your doctor will monitor your reaction to Ancotil. Possible side effects include:
Less frequent side effects include:
If you are concerned about any of these side effects, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly (see details below). By reporting side effects, you can help provide more information on the safety of this medicine.
For the United Kingdom:
For the Republic of Ireland:
5. HOW ANCOTIL SOLUTION FOR INFUSION IS STORED
6. FURTHER INFORMATION
What Ancotil Solution for Infusion contains
Active substance: Flucytosine. Each infusion bottle contains 2.5 g in 250 ml (1 g in 100 ml) of flucytosine
Other ingredients: Sodium chloride, tromethamine, hydrochloric acid, and water for injections.
What Ancotil Solution for Infusion looks like and contents of the pack
Marketing Authorisation Holder
For any information about this medicine, please contact the Marketing Authorisation Holder.
This leaflet was last revised in April 2017.
Sky Way House, Parsonage Road, Takeley, Bishop's Stortford, CM22 6PU
0845 460 0002
+44 (0)1748 828 810
0845 460 0000
+44 (0)1748 828 810
+44 (0)1748 828 801