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The eMC  

Last Updated 25 Feb 2014

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Tirofiban hydrochloride 12.5mg/250ml infusion bags

Tirofiban hydrochloride (tye-roe-fye-ban hi-droh-clor-ride) is a medicine which is used in treatment of myocardial infarction.

The information in this Medicine Guide for Tirofiban varies according to the condition being treated and the particular preparation used.

There are 2 preparations of Tirofiban available. If Tirofiban hydrochloride 12.5mg/250ml infusion bags is not the preparation you are looking for, please select from the drop down list below.

Select your preparation (type) of Tirofiban

Tirofiban hydrochloride 12.5mg/250ml infusion bags

Information specific to Tirofiban hydrochloride 12.5mg/250ml infusion bags when used in Heart attack

Your medicine

Tirofiban hydrochloride is an anti-platelet medicine. It helps stop platelets in the blood from sticking together and forming clots in blood vessels. Tirofiban hydrochloride is used in combination with other medicines and treatments in the management of heart attacks or other problems affecting blood supply to the heart.

Tirofiban hydrochloride is usually given to you by a healthcare professional. The person responsible for giving you your medicine will make sure that you get the right dose.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber or someone involved in your medical care.

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When to take your medicine

The person with responsibility for giving you your medicine will make sure that you have your medicine at the prescribed times.

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How to take your medicine

This medicine will be given to you as an injection. If you have any concerns about this medicine or how this will be given to you, talk to someone who is involved in your medical care.

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Taking too much of your medicine

Having extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems.

In the case of Tirofiban hydrochloride, the person who is responsible for giving you your medicine will make sure that you are given the correct dose.

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Stopping your medicine

The person in charge of your care will make the decision about when you should stop this medicine. If you experience any problems while having this medicine, talk to someone who is involved in your medical care.

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Looking after your medicine

As Tirofiban hydrochloride will be given to you as an injection, it will usually be stored by the medical team.

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Whether this medicine is suitable for you

Tirofiban hydrochloride is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

  • are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
  • are female
  • are in shock due to heart problems
  • are suspected to have certain types of circulation problems
  • have a low body weight
  • have a medical condition that makes you prone to bleeding
  • have a peptic ulcer or have had a peptic ulcer within the past three months
  • have blood in your stools or urine
  • have eye or eyesight problems
  • have had a recent injury or injection into the spine
  • have had a stroke within the past 30 days
  • have had an operation or procedure to break up kidney stones within the past two weeks
  • have had an organ biopsy within the past two weeks
  • have had blood problems caused by Tirofiban hydrochloride or another medicine in the same group as Tirofiban hydrochloride
  • have had surgery or have suffered from a traumatic injury within the past three months
  • have had to be resuscitated within the past two weeks
  • have high blood pressure which is not well controlled
  • have kidney problems
  • have or have had a medical condition that affects the brain
  • have or have had bleeding problems such as gastrointestinal bleeding within the past 30 days
  • have or have had certain heart or circulation problems
  • have or have had liver problems
  • have or have had problems with your blood or blood clotting

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for someone who is under the age of 18 years.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests:

  • to determine whether or not the medicine is suitable and whether it must be prescribed with extra care
  • to check that this medicine is not having any undesired effects
  • to confirm that this is the right dose

Over time it is possible that Tirofiban hydrochloride can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Tirofiban hydrochloride has become unsuitable, it is important that the prescriber is contacted immediately.

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Side-effects

A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.

Very common: More than 1 in 10 people who have Tirofiban hydrochloride

Common: More than 1 in 100 people who have Tirofiban hydrochloride

  • abnormal laboratory test results
  • coughing blood

Uncommon: More than 1 in 1000 people who have Tirofiban hydrochloride

The frequency of these side-effects is unknown

If you feel unwell or if you have concerns about a side-effect, tell the person looking after you immediately.

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Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Tirofiban hydrochloride:

The following types of medicine may interact with Tirofiban hydrochloride:

If you are taking Tirofiban hydrochloride and one of the above medicines or types of medicines, make sure your prescriber knows about it.

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Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.

If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Tirofiban hydrochloride.

Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.

If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.

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Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Tirofiban hydrochloride:

  • this medicine could affect your ability to drive or operate machinery. However, its impact on someone driving or operating machinery may not be relevant
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Diet

Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Tirofiban hydrochloride:

  • there are no specific foods that you must exclude from your diet when having Tirofiban hydrochloride
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Alcohol

Alcohol can interact with certain medicines.

In the case of Tirofiban hydrochloride:

  • there are no known interactions between alcohol and Tirofiban hydrochloride
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Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Tirofiban hydrochloride:

  • the use of this medicine during pregnancy is not recommended. You should only have this medicine during pregnancy if your doctor thinks that you need it

You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.

If the decision is that you should not have Tirofiban hydrochloride, then you should discuss whether there is an alternative medicine that you could take during pregnancy.

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Breast-feeding

Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Tirofiban hydrochloride:

  • women who are having Tirofiban hydrochloride should not breast-feed

Before you have your baby you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.

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Ingredients of your medicine

Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. They may also be used to prolong the life of the medicine.

This medicine contains tirofiban hydrochloride.

We are unable to list all of the ingredients for your medicine here. For a full list, you should refer to the patient information leaflet that comes with this medicine or ask your prescriber. You should check that you are able to take the ingredients of your medicine, especially if you have any allergies.

If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Tirofiban hydrochloride before, do not take Tirofiban hydrochloride. Talk to your prescriber, pharmacist or nurse as soon as possible.

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Tirofiban hydrochloride, Version 8, last updated 25 Feb 2014