This site uses cookies. By continuing to browse the site you are agreeing to our policy on the use of cookies. Find out more here.

Continue >
The eMC  

Last Updated 10 Apr 2015

You are viewing:

Bridion 200mg/2ml solution for injection vials

Bridion (brid-ee-on) is a medicine which is used in reversal of a neuromuscular block. Bridion contains sugammadex sodium. It is supplied by Merck Sharp & Dohme Limited.

The information in this Medicine Guide for Bridion varies according to the condition being treated and the particular preparation used.

There are 2 preparations of Bridion available. If Bridion 200mg/2ml solution for injection vials is not the preparation you are looking for, please select from the drop down list below.

Select your preparation (type) of Bridion

Bridion 200mg/2ml solution for injection vials

Information specific to Bridion 200mg/2ml solution for injection vials when used in reversal of a neuromuscular block

Print this medicine guide

Can't read the PDF? Download Adobe Reader at

Your medicine

Bridion speeds-up recovery from the effects of muscle relaxants that are used during surgery. It reverses the effects of the muscle relaxants rocuronium and vercuronium.

Muscle relaxants are given as part of anaesthesia to prevent muscle movement during some types of surgical procedures. Because muscle relaxants prevent normal breathing, you need to be on a ventilator during the time the muscle relaxant is having an effect.

Bridion works by deactivating the muscle relaxant and stops the muscle relaxant from having an effect. This speeds-up recovery from the anaesthetic process and reduces the amount of time that a ventilator is needed.

Bridion is given to you by a healthcare professional. The person responsible for giving you your medicine will make sure that you get the right dose.

If you feel unwell after having the medicine then talk to your prescriber or someone involved in your medical care.

Back to top

When to take your medicine

The person with responsibility for giving you your medicine will make sure that you have your medicine at the prescribed times.

Back to top

How to take your medicine

This medicine will be given to you as an injection. If you have any concerns about this medicine or how this will be given to you, talk to someone who is involved in your medical care.

Back to top

Taking too much of your medicine

Having extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems.

In the case of Bridion, the person who is responsible for giving you your medicine will make sure that you are given the correct dose.

Back to top

Stopping your medicine

Your medical team will give this medicine to you until it has had its intended effect.

If you have any questions about this medicine, talk to someone who is involved in your medical care.

Back to top

Looking after your medicine

As Bridion will be given to you as an injection, it will usually be stored by the medical team.

Back to top

Whether this medicine is suitable for you

Bridion is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child who is under two years of age.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests:

  • to check that this medicine is not having any undesired effects

While you are being treated with Bridion you will be continuously assessed and monitored by a member of the medical team.

Back to top


A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.

Common: More than 1 in 100 people who have Bridion:

  • anaesthetic complications before or during surgery such as movement of an arm, leg or body, waking up or an awareness, coughing, grimacing or sucking on the tube which is placed in the windpipe to keep the airway open

Uncommon: More than 1 in 1000 people who have Bridion:

  • hypersensitivity reactions including anaphylactic reactions or shock - some of these may be fatal. Symptoms include flushing, lowering of blood pressure, increased heart rate, swelling of the tongue or throat, lung problems or skin reactions such as urticaria or erythematous rash

The frequency of these side-effects is unknown:

  • bleeding in people with bleeding disorders
  • bronchospasm in people who have lung problems
  • flushing
  • may affect the results for certain tests
  • muscle weakness or paralysis after the operation
  • nausea
  • slower heart rate - this may lead to cardiac arrest
  • taste changes

If you feel unwell or if you have concerns about a side-effect, tell the person looking after you immediately.

Back to top

Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Bridion:

The following types of medicine may interact with Bridion:

If you are taking Bridion and one of the above medicines or types of medicines, make sure your prescriber knows about it.

Back to top

Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.

If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Bridion.

Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.

If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.

Back to top

Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Bridion:

  • as this medicine is only normally used in hospitals, its impact on someone driving or operating machinery may not be relevant

You should ask a member of your medical team how long you need to wait before you can drive or operate machinery after you have had Bridion.

Back to top


Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Bridion:

  • there are no specific foods that you must exclude from your diet when having Bridion
Back to top


Alcohol can interact with certain medicines.

In the case of Bridion:

  • there are no known interactions between alcohol and Bridion
Back to top

Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Bridion:

You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.

If the decision is that you should not have Bridion, then you should discuss whether there is an alternative medicine that you could take during pregnancy.

Back to top


Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Bridion:

  • it is not known whether this medicine passes into breast milk

Women who are planning to breast-feed while having Bridion must inform their doctor or midwife.

Back to top

Ingredients of your medicine

Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. Some may be used to prolong the life of the medicine.

Bridion contains:

If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Bridion before, do not have Bridion. Talk to your prescriber, pharmacist or nurse as soon as possible.

Back to top

Bridion, Version 10, last updated 10 Apr 2015