Last Updated 27 Mar 2013
The information in this Medicine Guide for Atriance varies according to the condition being treated and the particular preparation used.
Information specific to Atriance 250mg/50ml solution for infusion vials when used in Blood and bone marrow cancers
Atriance is used to treat acute lymphocytic leukaemia or lymphocytic lymphoma. It is only given to people who have not responded to, or whose cancer has returned, after having had other treatments for cancer.
Your medical team will discuss with you the options for treating your cancer. They will take into account factors such as the type of cancer, where it is, which stage it is at and whether you have had treatment before. The results of blood tests and other investigations will also be considered.
How well you feel and how you are likely to cope with treatment is also important.
Your cancer treatment will usually consist of a treatment session with Atriance followed by a break of a number of days before the next treatment session with Atriance. This cycle may be repeated many times as part of your cancer treatment.
Atriance works by damaging cancer cells in the body. Atriance also affects healthy cells and treatment with Atriance may damage your immune system. Your medical team may arrange for you to have some blood tests to check how well your immune system is working.
Atriance damages large numbers of cancer cells and treatment with it may lead to a condition called tumour lysis syndrome. You may be given extra fluid into a vein during your treatment with Atriance to prevent complications from tumour lysis syndrome.
As Atriance will be given to you as an injection, it will usually be stored by the medical team.
Atriance is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.
Over time it is possible that Atriance can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Atriance has become unsuitable, it is important that the prescriber is contacted immediately.
Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.
Some side-effects may be serious while others may only be a mild inconvenience.
Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.
If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call NHS Direct on 0845 46 47.
The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.
Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.
Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.
Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.
When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.
In the case of Atriance:
You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.
Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.
In the case of Atriance:
If you are planning to become pregnant or father a child you should discuss your personal circumstances with your prescriber. This is so that together you can make a decision about whether you are going to take Atriance or if there is an alternative medicine that you could take.
Certain medicines can pass into breast milk and may reach your baby through breast-feeding.
In the case of Atriance:
Before you have your baby you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.
Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. Some may be used to prolong the life of the medicine.
If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Atriance before, do not have Atriance. Talk to your prescriber, pharmacist or nurse as soon as possible.
Atriance, Version 8, last updated 27 Mar 2013