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The eMC  

Last Updated 24 Jan 2011

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Lopresor 100mg tablets

Lopresor (Loh-press-or) is a medicine which is used in a number of conditions. Lopresor contains metoprolol tartrate. It is supplied by Recordati Pharmaceuticals Limited.

The information in this Medicine Guide for Lopresor varies according to the condition being treated and the particular preparation used.

There are 2 preparations of Lopresor available. If Lopresor 100mg tablets is not the preparation you are looking for, please select from the drop down list below.

Select your preparation (type) of Lopresor

Lopresor 100mg tablets

Information specific to Lopresor 100mg tablets when used in heart attacks

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Your medicine

Lopresor is used to treat a number of conditions that relate to the heart and circulation such as high blood pressure, a heart attack, angina or heart rhythm disorders. It is also used in the treatment of an overactive thyroid gland alongside other therapies. Lopresor also helps prevent migraine attacks.

Lopresor belongs to a class of medicines called beta-blockers. It works by blocking the effects of a chemical in the body. Blocking this chemical has many effects on the heart and circulation. It slows the heart rate, reduces the force with which the heart muscle contracts and reduces the volume of blood pumped out of the heart in a minute.

Other information about Lopresor:

  • your prescriber may vary the dose of your medicine to find what is best for you
  • if you are about to have surgery you may need to stop taking Lopresor before you can have your operation. For more information speak to a member of your medical team

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

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When to take your medicine

Some medicines work best if they are taken at a specific time of day. Getting the most from your medicine can also be affected by what you eat, when you eat and the times at which you take other medicines. Make sure you follow any specific instructions given to you by your prescriber or that are in the Patient Information Leaflet that comes with this medicine.

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How to take your medicine

Some medicines have specific instructions about how to take them. This is because they work better when taken correctly. These instructions can include getting the right dose and special instructions for preparing the medicine. Make sure you follow any specific instructions given to you by your prescriber or that are in the Patient Information Leaflet that comes with this medicine.

In the case of Lopresor:

  • swallow the medicine whole with a glass of water
  • take your medicine in its original form. You must not chew it

If you are having problems taking this medicine, you should talk to your prescriber or pharmacist. They may be able to give you advice on other ways to take your medicine or other medicines that are easier for you to take.

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Taking too much of your medicine

Taking extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems. If you take extra doses of your medicine, you must get medical advice immediately. You may need a test to assess the effect of taking extra doses. This is because the effects of taking too much medicine are very complex so it is very important that you seek medical advice.

Contact your prescriber, pharmacist, specialist clinic or call 111 for advice.

Make sure you take all of your medicine containers with you if you are advised to go to hospital.

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Stopping your medicine

If you are not having any problems taking this medicine then do not stop taking it, unless advised to do so by your prescriber. If, however, you find that this medicine is causing you problems then you should talk to your prescriber about your concerns.

In some instances stopping Lopresor abruptly can worsen your condition. If your doctor decides that it is best that you do not take this medicine any more, they may advise you to reduce the dose gradually over time.

If you are in any doubt, contact your prescriber, pharmacist, specialist clinic or call 111.

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Looking after your medicine

The instructions on how you should keep your medicine are on the pharmacy label. You should keep your medicine in the original container. This will help to keep your medicine in the best condition and also allow you to check the instructions. Do not take the medicine if the packaging appears to have been tampered with or if the medicine shows any signs of damage. Make sure that the medicine is out of the sight and reach of children.

In the case of Lopresor:

You must not take the medicine after the expiry date shown on the packaging. If you have any unused medicine, return it to your pharmacist who will dispose of it safely.

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Whether this medicine is suitable for you

Lopresor is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests:

  • to check that this medicine is not having any undesired effects

Over time it is possible that Lopresor can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Lopresor has become unsuitable, it is important that the prescriber is contacted immediately.

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A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.

Common: More than 1 in 100 people who take Lopresor:

  • a drop in blood pressure on standing or sitting up - you may faint or lose consciousness briefly
  • feeling dizzy
  • headaches
  • nausea
  • shortness of breath on exertion
  • slow heart rate - if your heartrate falls below 50-55 heart beats per minute you should immediately seek medical advice
  • stomach pain
  • tiredness
  • vomiting

Rare: More than 1 in 10,000 people who take Lopresor:

Very rare: Fewer than 1 in 10,000 people who take Lopresor:

  • abnormal laboratory test results
  • arthritis
  • changes in libido
  • changes in personality
  • chest pain
  • dry mouth
  • eye or eyesight problems such as blurred vision, dry eyes or irritation - seek immediate medical advice if you get any eye problems such as irritation in the eye or dry eyes
  • gangrene in people with circulation problems
  • hair loss
  • hallucinations
  • hearing problems such as hearing loss or deafness
  • photosensitivity
  • rhinitis
  • sexual dysfunction
  • sweating
  • thrombocytopenia
  • tinnitus
  • weight gain
  • worsening of psoriasis

The frequency of these side-effects is unknown:

  • confusion
  • hiding symptoms of thyrotoxicosis
  • high levels of triglycerides in the blood
  • liver problems
  • low blood sugar levels in people with diabetes - you may need to adjust your anti-diabetic therapy. You may also find that the signs and symptoms of low blood sugar levels may be hidden
  • Peyronie's disease
  • retroperitoneal fibrosis
  • worsening of anaphylactic type reactions
  • worsening of angina in people with Prinzmetal's angina

If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call 111.

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Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Lopresor:

The following types of medicine may interact with Lopresor:

If you are taking Lopresor and one of the above medicines or types of medicines, make sure your prescriber knows about it.

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Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.

If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Lopresor.

Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.

If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.

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Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Lopresor:

  • this medicine could affect your ability to drive or operate machinery

You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

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Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Lopresor:

  • there are no specific foods that you must exclude from your diet when taking Lopresor
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Alcohol can interact with certain medicines.

In the case of Lopresor:

You should seek advice from your prescriber as to whether you may drink alcohol while taking this medicine.

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Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Lopresor:

  • you should only take this medicine during pregnancy if your doctor thinks that you need it
  • if you take this medicine during your pregnancy, your baby may need to have some monitoring after birth

You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.

If the decision is that you should not have Lopresor, then you should discuss whether there is an alternative medicine that you could take during pregnancy.

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Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Lopresor:

  • you should only take this medicine while breast-feeding if your doctor thinks you need it

Before you have your baby you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. You should only breast-feed your baby while taking this medicine on the advice of your doctor or midwife.

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Ingredients of your medicine

Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. They are also added to improve the medicine's taste and appearance and to make it easier to take. Some may be used to prolong the life of the medicine.

You should check that you are able to take the ingredients in your medicine, especially if you have any allergies.

Lopresor contains:

  • aerosil 200
  • avicel PH101
  • dispersed blue (E132)
  • hydroxypropyl methylcellulose
  • magnesium stearate
  • polysorbate 80
  • povidone
  • purified talc special
  • sodium starch glycollate
  • titanium dioxide (E171)

If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Lopresor before, do not take Lopresor. Talk to your prescriber, pharmacist or nurse as soon as possible.

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Lopresor, Version 7, last updated 24 Jan 2011